Neural Stem Cells and Ischemic Brain
Recommended Citation
Zhang Z, and Chopp M. Neural stem cells and ischemic bra. J Stroke 2016; 18(3):267-272.
Document Type
Article
Publication Date
9-1-2016
Publication Title
J Stroke
Abstract
Stroke activates neural stem cells in the ventricular-subventricular zone (V/SVZ) of the lateral ventricle, which increases neuroblasts and oligodendrocyte progenitor cells (OPCs). Within the ischemic brain, neural stem cells, neuroblasts and OPCs appear to actively communicate with cerebral endothelial cells and other brain parenchymal cells to mediate ischemic brain repair; however, stroke-induced neurogenesis unlikely plays any significant roles in neuronal replacement. In this mini-review, we will discuss recent findings how intercellular communications between stroke-induced neurogenesis and oligodendrogenesis and brain parenchymal cells could potentially facilitate brain repair processes.
PubMed ID
27488979
Volume
18
Issue
3
First Page
267
Last Page
272
