From medications to surgery: advances in the treatment of motor complications in Parkinson's disease
Recommended Citation
Nagao KJ, and Patel NJ. From medications to surgery: Advances in the treatment of motor complications in Parkinson's disease. Drugs in Context 2019; 8.
Document Type
Article
Publication Date
8-13-2019
Publication Title
Drugs Context
Abstract
Motor complications are responsible for the large burden of disability and poor quality of life in Parkinson's disease (PD). The pulsatile nature of stimulation with oral dopaminergic therapies due to relatively short pharmacokinetic profiles and dysfunctional gastrointestinal absorption have been attributed to the development of PD motor complications. In this review, we will provide an overview of the pharmacologic and surgical therapies currently available and under investigation for the treatment of motor fluctuations and dyskinesia.
PubMed ID
31516532
Volume
8