Recommended Citation
Zillgitt A, Haykal MA, Elisevich K, Patra S, Sherburn F, Bowyer SM, and Burdette DE. Magnetoencephalography-identified preictal spiking correlates to preictal spiking on stereotactic EEG. Epilepsy Behav Rep 2022; 19:100538.
Document Type
Article
Publication Date
3-24-2022
Publication Title
Epilepsy Behav Rep
Abstract
Magnetoencephalography (MEG) is a noninvasive diagnostic modality that directly measures neuronal signaling by recording the magnetic field created from dendritic, intracellular, electrical currents of the neuron at the surface of the head. In clinical practice, MEG is used in the epilepsy presurgical evaluation and most commonly is an "interictal" study that can provide source localization of spike-wave discharges. However, seizures may be recorded during MEG ("ictal MEG") and mapping of these discharges may provide more accurate localization of the seizure onset zone. In addition, spike-negative EEG with unique MEG spike-waves may be present in up to 1/3 of MEG studies and unique MEG seizures (EEG-negative seizures) have been reported. This case report describes a patient with unique MEG seizures that exhibited MEG pre-ictal spiking in a tight cluster consistent with the independent interictal epileptiform activity. Stereotactic EEG demonstrated pre-ictal spiking concordant with the MEG pre-ictal spiking.
PubMed ID
35573060
Volume
19
First Page
100538
Last Page
100538
