Neuro-Behçet's Syndrome: A Case Report

Authors

David I. LeRoy, Henry Ford HealthFollow
Elaine Ognjanovski, Henry Ford HealthFollow
Silvia Menkes, Henry Ford HealthFollow
Kristen Kenny, Henry Ford HealthFollow
Cassie T. Konja, Henry Ford HealthFollow

Recommended Citation

LeRoy DI, Ognjanovski E, Menkes S, Kenny K, and Konja C. Neuro-Behçet's Syndrome: A Case Report. Cureus 2025;17(5):e84421.

Document Type

Article

Publication Date

5-1-2025

Publication Title

Cureus

Keywords

behçet's syndrome; infliximab; neuro-behçet's syndrome; seizure; status epilepticus

Abstract

Behçet's syndrome is a systemic vasculitis characterized by recurrent oral and genital ulcers, uveitis, and often involvement of multiple organ systems. Neurological involvement is a rare complication of Behçet's syndrome and is associated with significant morbidity and mortality. Neuro-Behçet's syndrome (NBS) is a combination of neurologic manifestations in a patient with Behçet's syndrome, including movement disorders, myelopathic syndrome, intracranial hypertension, and a multiple sclerosis-like presentation. Diagnosis of NBS can be challenging due to the wide range of clinical presentations. Although previous research has aided in advancing the understanding of the pathophysiology and treatment of systemic Behçet's syndrome, there is a lack of randomized controlled studies involving the treatment of NBS. This case report describes a patient with NBS who experienced a complex hospital course, highlighting the need for a multidisciplinary team approach to address various complications.

PubMed ID

40539167

Volume

17

Issue

5

First Page

84421

Last Page

84421