Reoperation for Recurrent Glioblastoma Multiforme
Recommended Citation
Robin AM, Lee I, and Kalkanis SN. Reoperation for recurrent glioblastoma multiforme. Neurosurg Clin N Am 2017; 28(3):407-428.
Document Type
Article
Publication Date
7-1-2017
Publication Title
Neurosurgery clinics of North America
Abstract
The role of reoperation for glioblastoma multiforme (GBM) recurrence is currently unknown. However, multiple studies have indicated that survival and quality of life are improved with a repeat operation at the time of disease recurrence. Prognosis is likely interdependent on several factors, including age, functional status, initial resection status, disease location, and surgical efficacy. However, there are significant data indicating no survival benefit for reoperation. This comprehensive literature review considering the controversial question of whether to operate for progressive or recurrent GBM seeks to evaluate the current available evidence and report on its conclusions.
Medical Subject Headings
Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Prognosis; Quality of Life; Reoperation
PubMed ID
28600015
Volume
28
Issue
3
First Page
407
Last Page
428