Clinical and research applications of a brain tumor tissue bank in the age of precision medicine
Recommended Citation
Snyder J, Poisson LM, Noushmehr H, Castro AV, de Carvalho AC, Robin A, Mukherjee A, Lee I, Walbert T. Clinical and research applications of a brain tumor tissue bank in the age of precision medicine. Per Med 2019; .
Document Type
Article
Publication Date
2-28-2019
Publication Title
Per Med
Abstract
Marked progress has been made recently in the treatment of patients with central nervous system (CNS) tumors, especially gliomas. However, because of the relative rarity of these tumors compared with other malignancies, advances in the molecular/genetic analysis leading to future targeted treatments rely on systematic, organized tissue banking. Several large multi-institutional efforts have utilized major tissue banks that have yielded valuable information that may lead to a better understanding of the pathogenesis of CNS tumors. This manuscript portrays best practices for the establishment and maintenance of a well-organized CNS tumor bank. In addition, annotation for clinical and research needs is explained. The potential benefits to clinical care, as well as basic science and translational research are also described.
PubMed ID
30816054
ePublication
ePub ahead of print
