Injection of adipose stem cells in the treatment of rotator cuff disease - a narrative review of current evidence

Authors

Jonathan R. Warren, Henry Ford HealthFollow
Lafi S. Khalil, Henry Ford HealthFollow
Alexander D. Pietroski, Henry Ford HealthFollow
Stephanie J. Muh, Henry Ford HealthFollow

Recommended Citation

Warren JR, Khalil LS, Pietroski AD, and Muh SJ. Injection of adipose stem cells in the treatment of rotator cuff disease - a narrative review of current evidence. Regen Med 2022; 17(7):477-489.

Document Type

Article

Publication Date

7-1-2022

Publication Title

Regen Med

Abstract

The purpose of this study is to summarize evidence for the use of adipose stem cell (ASC) injections in the treatment of rotator cuff tears (RCT) and identify future areas of study. A thorough literature search was performed to identify studies investigating the use of ASC injections in the treatment of RCTs. Among animal trials, it is unclear whether ASCs are of benefit for rotator cuff repair. In clinical trials, ASC injection may reduce retear rate with otherwise equivocal clinical outcomes. Although ASC injection may be safe, the literature does not provide a clear consensus as to the efficacy of ASC injections, nor does it delineate which patients would benefit most from this treatment.

Medical Subject Headings

Adipocytes; Adipose Tissue; Animals; Humans; Rotator Cuff; Rotator Cuff Injuries; Stem Cells; Treatment Outcome

PubMed ID

35586993

Volume

17

Issue

7

First Page

477

Last Page

489