Translational Aspects of 3D and 4D Printing and Bioprinting

Document Type

Article

Publication Date

7-9-2024

Publication Title

Adv Healthc Mater

Abstract

Three-dimensional (3D) printed medical devices include orthopedic and craniofacial implants, surgical tools, and external prosthetics that have been directly used in patients. While the advances of additive manufacturing techniques in the production of medical devices have been on the rise, clinical translation of living cellular constructs face significant limitations in terms of regulatory affairs, process technology, and materials development. In this perspective, the current status-quo of 3D and four-dimensional (4D) (bio)printing is summarized, current advancements are discussed and the challenges that need to be addressed for improved industrial translation and clinical applications of bioprinting are highlighted. It is focused on a multidisciplinary approach in discussing the key translational considerations, from the perspective of industry, regulatory bodies, funding strategies, and future directions.

PubMed ID

38979857

ePublication

ePub ahead of print

First Page

2400463

Last Page

2400463

Share

COinS