Salivary gland hyalinizing clear cell carcinoma with cutaneous metastasis: a rare and deceptive tumor

Authors

Rand Abou Shaar, Henry Ford HealthFollow
Shereen Zia, Henry Ford HealthFollow
Mohamed Alhamar, Henry Ford HealthFollow
Teresa Romano, Henry Ford HealthFollow
Brandon Shaw, Henry Ford HealthFollow
Christian Keller, Henry Ford HealthFollow
Ben J. Friedman, Henry Ford HealthFollow

Recommended Citation

Abou Shaar R, Zia S, Alhamar M, Romano T, Shaw B, Keller C, and Friedman BJ. Salivary gland hyalinizing clear cell carcinoma with cutaneous metastasis: a rare and deceptive tumor. J Cutan Pathol 2020.

Document Type

Article

Publication Date

7-8-2020

Publication Title

Journal of cutaneous pathology

Abstract

Clear cell carcinoma (CCC) is an uncommon malignant tumor of minor salivary glands. It characteristically has a low-grade morphology and a favorable outcome by most reports. An EWSR1-ATF1 fusion can be detected in the majority of cases. We present a rare case of CCC which had an aggressive course with the development of cutaneous metastases. Practicing dermatopathologists should be aware of this tumor given its low-grade appearance and histologic resemblance to other primary cutaneous adnexal and metastatic neoplasms.

PubMed ID

32640078

ePublication

ePub ahead of print