Adipocytic Differentiation in a Sertoli Cell Tumor
Recommended Citation
Molina J, Dabaja A, Gupta N, Alruwaii FI, Hassan O, and Al-Obaidy KI. Adipocytic Differentiation in a Sertoli Cell Tumor. Int J Surg Pathol 2023.
Document Type
Article
Publication Date
11-28-2023
Publication Title
International journal of surgical pathology
Abstract
Testicular sex cord-stromal tumors are clonal neoplasms, with the majority being of Leydig cell followed by Sertoli cell origins. In Leydig cell tumors, adipocytic differentiation has been previously reported as a possible distinguishing feature, which has not been reported in other sex cord-stromal tumors. Herein, we report a case of a 48-year-old man who presented with an incidentally discovered 1.1 cm testicular mass, for which he underwent partial orchiectomy. Microscopically, the tumor showed features consistent with sex cord-stromal tumor with strong and diffuse nuclear and cytoplasmic reaction for B-catenin immunohistochemistry, supporting the diagnosis of Sertoli cell tumor. A novel adipocytic differentiation, reported previously in Leydig cell tumors, was present in this tumor.
PubMed ID
38018140
ePublication
ePub ahead of print
