Zoonotic Bacterial Infections Triggering Cytokine Storm Syndrome

Document Type

Article

Publication Date

1-1-2024

Publication Title

Advances in experimental medicine and biology

Abstract

Zoonotic infections can result in life-threatening complications that can manifest with hemophagocytic lymphohistiocytosis (HLH)/cytokine storm syndrome (CSS). Bacteria constitute the largest group of zoonotic infection-related HLH cases. The growing list of zoonotic bacterial infections associated with HLH/CSS include Brucella spp., Rickettsia spp., Ehrlichia, Coxiella burnetii, Mycobacterium spp., and Bartonella spp. Patients most commonly present with fever, cytopenias, hepatosplenomegaly, myalgias, and less frequently with rash, jaundice, and lymphadenopathy.

Medical Subject Headings

Humans; Cytokine Release Syndrome; Animals; Bacterial Zoonoses; Lymphohistiocytosis, Hemophagocytic; Zoonoses

PubMed ID

39117822

Volume

1448

First Page

285

Last Page

291

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