Is Shorter Better in Oncology Patients, Too? A Retrospective Cohort Study of Short- Versus Long-Course Antibiotic Therapy for Uncomplicated Infections in Solid Tumor Patients Receiving Care in Ambulatory Oncology Clinics

Authors

Christen J. Arena, Henry Ford HealthFollow
Beisan El-Tatari, Henry Ford HealthFollow
Kristen Lovric, Henry Ford HealthFollow
Sage B. Greenlee, Henry Ford HealthFollow
Rachel M. Kenney, Henry Ford HealthFollow
Shirish M. Gadgeel, Henry Ford HealthFollow
Katelyn M. Patterson, Henry Ford HealthFollow
Anita B. Shallal, Henry Ford HealthFollow
George J. Alangaden, Henry Ford HealthFollow
Susan L. Davis, Henry Ford HealthFollow
Michael P. Veve, Henry Ford HealthFollow

Recommended Citation

Arena CJ, El-Tatari B, Lovric K, Greenlee SB, Kenney RM, Gadgeel SM, Patterson K, Shallal AB, Alangaden GJ, Davis SL, and Veve MP. Is Shorter Better in Oncology Patients, Too? A Retrospective Cohort Study of Short- Versus Long-Course Antibiotic Therapy for Uncomplicated Infections in Solid Tumor Patients Receiving Care in Ambulatory Oncology Clinics. Open Forum Infect Dis 2025;12(9):ofaf505.

Document Type

Article

Publication Date

9-1-2025

Publication Title

Open Forum Infect Dis

Abstract

This retrospective cohort study evaluated short- versus long-course antibiotics for uncomplicated infections in ambulatory solid tumor patients. Among 303 patients, outcomes were similar between groups, including infection recurrence, treatment delays, and adverse events. Short-course therapy was not associated with worse outcomes, suggesting it may be a viable alternative.

Medical Subject Headings

Oncology; ambulatory stewardship; antimicrobial stewardship; immunocompromised; outpatient stewardship; short vs. long antibiotic durations; solid tumor

PubMed ID

40908971

Volume

12

Issue

9

First Page

505

Last Page

505