Serotonin Syndrome Following Methylene Blue Administration for Vasoplegic Syndrome

Document Type

Article

Publication Date

4-1-2016

Publication Title

Journal of cardiac surgery

Keywords

Citalopram/adverse effects, Drug Synergism, Female, Heart-Assist Devices, Humans, Methylene Blue/administration & dosage/adverse effects, Middle Aged, Prosthesis Implantation, Serotonin Syndrome/chemically induced, Selective Serotonin Reuptake Inhibitors/adverse effects, Severity of Illness Index, Vasoplegia/therapy

Abstract

Methylene blue (MB) has been used for additional blood pressure support in patients who develop severe, refractory vasoplegia; however, MB can induce serotonin syndrome, especially when used in conjunction with other serotonergic agents. We describe a case of serotonin syndrome in a patient who received MB for vasoplegic syndrome after left ventricular assist device implantation and discuss its presentation and management.

Medical Subject Headings

Citalopram/adverse effects; Drug Synergism; Female; Heart-Assist Devices; Humans; Methylene Blue/administration & dosage/adverse effects; Middle Aged; Prosthesis Implantation; Serotonin Syndrome/chemically induced; Selective Serotonin Reuptake Inhibitors/adverse effects; Severity of Illness Index; Vasoplegia/therapy

PubMed ID

26934199

Volume

31

Issue

4

First Page

208

Last Page

210

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