Lower rates of emergency visits and hospitalizations among chronic hepatitis C patients with sustained virological response to interferon-free direct-acting antiviral therapy (2014-2018)
Recommended Citation
Gordon SC, Teshale EH, Spradling PR, Moorman AC, Boscarino JA, Schmidt MA, Daida YG, Rupp LB, Trudeau S, Zhang J, and Lu M. Lower rates of emergency visits and hospitalizations among chronic hepatitis C patients with sustained virological response to interferon-free direct-acting antiviral therapy (2014-2018). Clin Infect Dis 2022.
Document Type
Article
Publication Date
2-11-2022
Publication Title
Clinical infectious diseases
Keywords
Antiviral Agents/therapeutic use, Emergency Service, Hospital, Hepacivirus, Hepatitis C, Chronic/drug therapy/epidemiology, Hospitalization, Humans, Interferons/therapeutic use, Ribavirin/therapeutic use, Sustained Virologic Response, Treatment Outcome, Ed, Hcv, Svr, healthcare utilization, race
Abstract
We compared rates of emergency department (ED) visits and hospitalizations between HCV patients who achieved sustained virological response (SVR) after direct-acting antiviral (DAA) therapy (cases) to matched controls. Among 3049 pairs, cases demonstrated lower rates of liver-related ED visits (P=.01) than controls; all-cause and liver-related hospitalization rates and hospitalized days were also lower in cases (P<.0001).
Medical Subject Headings
Antiviral Agents/therapeutic use; Emergency Service; Hospital; Hepacivirus; Hepatitis C; Chronic/drug therapy/epidemiology; Hospitalization; Humans; Interferons/therapeutic use; Ribavirin/therapeutic use; Sustained Virologic Response; Treatment Outcome; Ed; Hcv; Svr; healthcare utilization; race
PubMed ID
35147184
ePublication
ePub ahead of print
Volume
75
Issue
8
First Page
1453
Last Page
1456
