The Association between Dietary Inflammatory Patterns and the Incidence of Frailty and Its Reversal in Older Adults: A Community-Based Longitudinal Follow-Up Study in Taiwan

Authors

Shu-Chun Chuang
Chao A. Hsiung
Meng-Hua Tao, Henry Ford HealthFollow
I-Chien Wu
Chiu-Wen Cheng
Wei-Ting Tseng
Marion M. Lee
Hsing-Yi Chang
Chih-Cheng Hsu

Recommended Citation

Chuang SC, Hsiung CA, Tao MH, Wu IC, Cheng CW, Tseng WT, Lee MM, Chang HY, and Hsu CC. The Association between Dietary Inflammatory Patterns and the Incidence of Frailty and Its Reversal in Older Adults: A Community-Based Longitudinal Follow-Up Study in Taiwan. Nutrients 2024; 16(17).

Document Type

Article

Publication Date

8-27-2024

Publication Title

Nutrients

Abstract

Dietary patterns related to inflammation have garnered great interest in disease prevention. The aims of this study were to evaluate whether a proinflammatory diet affects the incidence of frailty and its reversal in a prospective follow-up study. Data were taken from 5663 community-dwelling individuals ≥ 55 years old in Taiwan. The energy-adjusted dietary inflammatory index (DII) and the Empirical Dietary Inflammatory Patterns-Healthy Aging Longitudinal Study in Taiwan (EDIP-HALT) at baseline were calculated using a food frequency questionnaire. Frailty was assessed with Fried's criteria in 2008-2013 and 2013-2020. Associations with changes in frailty status were assessed with multinominal logistic regressions and adjusted for major confounders. Higher EDIP-HALST scores (proinflammatory) were associated with higher odds of frailty among baseline robust participants in men (OR = 2.44, 95% CI = 1.42-4.21, p-(trend) < 0.01) and broadline associated in women (OR = 1.96, 95% CI = 0.96-3.98, p-(trend) = 0.05), but associated with lower odds of reversing back to robust among baseline prefrail participants. However, the later association was only observed in women, and the relationships were stronger in the middle tertile (second vs. first tertile, OR = 0.40, 95% CI = 0.25-0.65). A pro-inflammatory diet pattern was associated with higher odds of frailty onset in baseline robust participants and lower odds of reversal in baseline prefrail female participants.

Medical Subject Headings

Humans; Taiwan; Male; Female; Aged; Frailty; Longitudinal Studies; Incidence; Inflammation; Middle Aged; Follow-Up Studies; Diet; Prospective Studies; Frail Elderly; Independent Living; Aged, 80 and over; Risk Factors

PubMed ID

39275178

Volume

16

Issue

17