Document Type

Article

Publication Date

9-1-2022

Publication Title

Respirology (Carlton, Vic.)

Abstract

Since the publication of a sham-controlled, randomized trial (AIR2) and subsequent marketing approval by the US Food and Drug Administration, we have significantly advanced our understanding of bronchial thermoplasty (BT)'s scientific basis, long-term safety, clinical efficacy and cost-effectiveness. In particular, the last 2 years have witnessed multiple research publications on several of these counts. In this review, we critically appraise our evolving understanding of BT's biologic underpinnings and clinical impact, offer an evidence-based patient workflow guide for the busy pulmonologist and highlight both current challenges as well as potential solutions for the researcher and the clinician.

PubMed ID

35692074

ePublication

ePub ahead of print

Volume

27

Issue

9

First Page

720

Last Page

729

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