Project #35: The Long-term Sustainability of the Respiratory Culture Nudge on Antibiotic Prescribing

Project #35: The Long-term Sustainability of the Respiratory Culture Nudge on Antibiotic Prescribing

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Unnecessary antibiotic use in respiratory infections contributes to adverse effects and excess cost. Successful and sustainable strategies are needed to encourage optimal antibiotic use, including discontinuation of excess broad-spectrum therapy. In 2016, HFHS Antimicrobial Stewardship Program standardized reporting of microbiology reports to emphasize the absence of certain bacteria in in respiratory culture samples. We previously demonstrated that this intervention improved antibiotic prescribing patterns and outcomes in patients empirically treated for pneumonia. However, many initially successful interventions fail to change long-term behavior, and the impact may dwindle over time. Thus, the purpose of this study was to evaluate the sustainability of the respiratory commensal flora report on prescribing patterns and patient outcomes. The specific aims of this intervention were to improve antibiotic prescribing through antibiotic de-escalation/discontinuation, decrease length of stay, and improve patient safety outcomes (by reducing acute kidney injury (AKI), C. difficile infection (CDI), all-cause hospital mortality).

Publication Date

3-16-2021

Project #35: The Long-term Sustainability of the Respiratory Culture Nudge on Antibiotic Prescribing

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