Recommended Citation
Huang Y, Zhao B, Chetty IJ, Brown S, Gordon J, and Wen N. Targeting accuracy of image-guided radiosurgery for intracranial lesions: A comparison across multiple linear accelerator platforms. Technol Cancer Res Treat 2015; 15(2):243-248.
Document Type
Article
Publication Date
4-1-2016
Publication Title
Technology in cancer research & treatment
Abstract
PURPOSE: To evaluate the overall positioning accuracy of image-guided intracranial radiosurgery across multiple linear accelerator platforms.
METHODS: A computed tomography scan with a slice thickness of 1.0 mm was acquired of an anthropomorphic head phantom in a BrainLAB U-frame mask. The phantom was embedded with three 5-mm diameter tungsten ball bearings, simulating a central, a left, and an anterior cranial lesion. The ball bearings were positioned to radiation isocenter under ExacTrac X-ray or cone-beam computed tomography image guidance on 3 Linacs: (1) ExacTrac X-ray localization on a Novalis Tx; (2) cone-beam computed tomography localization on the Novalis Tx; (3) cone-beam computed tomography localization on a TrueBeam; and (4) cone-beam computed tomography localization on an Edge. Each ball bearing was positioned 5 times to the radiation isocenter with different initial setup error following the 4 image guidance procedures on the 3 Linacs, and the mean (µ) and one standard deviation (σ) of the residual error were compared.
RESULTS: Averaged overall 3 ball bearing locations, the vector length of the residual setup error in mm (µ ± σ) was 0.6 ± 0.2, 1.0 ± 0.5, 0.2 ± 0.1, and 0.3 ± 0.1 on ExacTrac X-ray localization on a Novalis Tx, cone-beam computed tomography localization on the Novalis Tx, cone-beam computed tomography localization on a TrueBeam, and cone-beam computed tomography localization on an Edge, with their range in mm being 0.4 to 1.1, 0.4 to 1.9, 0.1 to 0.5, and 0.2 to 0.6, respectively. The congruence between imaging and radiation isocenters in mm was 0.6 ± 0.1, 0.7 ± 0.1, 0.3 ± 0.1, and 0.2 ± 0.1, for the 4 systems, respectively.
CONCLUSIONS: Targeting accuracy comparable to frame-based stereotactic radiosurgery can be achieved with image-guided intracranial stereotactic radiosurgery treatment.
Medical Subject Headings
Brain Neoplasms; Calibration; Humans; Phantoms, Imaging; Radiosurgery; Radiotherapy Planning, Computer-Assisted
PubMed ID
25759427
Volume
15
Issue
2
First Page
243
Last Page
248
