Primary target volume delineation for radiotherapy in nasopharyngeal carcinoma: CSTRO, CACA, CSCO, HNCIG, ESTRO, and ASTRO guidelines and contouring atlas
Recommended Citation
Tang LL, Huang CL, Lin SJ, Le QT, O'Sullivan B, Yom SS, Huang SH, Chan AW, Lee N, Pan JJ, Mejia MBA, Ahn YC, Wong KCW, McDowell L, Orlandi E, Friborg J, Chen YP, Yasuda K, Kodaira T, Whitley AC, King AD, Prajogi GB, Hahn E, Lin JC, Kiyota N, Lee V, Ji PJ, Hitchcock Y, Hoebers F, Blanchard P, Moon SH, Wan Ishak WZ, Harrington KJ, Yang KY, Colevas AD, Lee A, Hu CS, Rosenthal D, Siddiqui F, Langendijk JA, Lang JY, Yi JL, Shen LF, Li JB, Liu LZ, Lee AWM, Mai HQ, Yang MK, Sun Y, Chua MLK, and Ma J. Primary target volume delineation for radiotherapy in nasopharyngeal carcinoma: CSTRO, CACA, CSCO, HNCIG, ESTRO, and ASTRO guidelines and contouring atlas. Lancet Oncol 2025;26(9):e477-e487.
Document Type
Article
Publication Date
9-1-2025
Publication Title
The lancet oncology
Abstract
The Chinese Society for Therapeutic Radiology Oncology, the Chinese Anti-Cancer Association, the Chinese Society of Clinical Oncology, Head and Neck Cancer International Group, the European Society for Radiotherapy and Oncology, and the American Society for Radiation Oncology jointly developed evidence-based guidelines and a contouring atlas for primary target volume delineation for radiotherapy in nasopharyngeal carcinoma. The guidelines systematically address three crucial challenges: margin design of clinical target volumes; target volume delineation after induction chemotherapy; and low-risk clinical target volume delineation based on local stepwise extension patterns. Based on a comprehensive systematic review and critical appraisal by an international multidisciplinary panel of 50 nasopharyngeal carcinoma specialists from 17 countries and regions, these guidelines are in keeping with advances in nasopharyngeal carcinoma diagnosis and treatment, embodying contemporary treatment concepts, and elaborating on the differences in practice. These guidelines aim to support global clinical practice in radiotherapy target volume delineation, substantially enhancing homogeneity and reducing variability in nasopharyngeal carcinoma target delineation.
Medical Subject Headings
Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Radiotherapy Planning; Computer-Assisted; Radiation Oncology
PubMed ID
40907526
Volume
26
Issue
9
First Page
477
Last Page
477
