Pediatric head and neck squamous cell carcinoma: Patient demographics, treatment trends and outcomes
Modh A, Gayar OH, Elshaikh MA, Paulino AC, and Siddiqui F. Pediatric head and neck squamous cell carcinoma: Patient demographics, treatment trends and outcomes. Int J Pediatr Otorhinolaryngol 2018; 106:21-25.
International journal of pediatric otorhinolaryngology
OBJECTIVES: To examine patient demographics, temporal and treatment trends, and survival outcomes of pediatric non-nasopharyngeal head and neck squamous cell carcinomas using the National Cancer Database.
METHODS: The National Cancer Database was queried for pediatric patients (age 0-19 years) diagnosed with squamous cell carcinoma of the head and neck (including oral cavity, oropharynx, nasal cavity, larynx, hypopharynx, and salivary glands) from 2004 to 2013.
RESULTS: Of 159 patients identified, the majority had oral cavity SCC (55%). There was no discernable change in incidence trends over the study period with the number of cases per year ranging from 10 to 20 (R
CONCLUSION: Although pediatric non-nasopharyngeal head and neck squamous cell carcinomas are rare, practitioners should be aware of this entity and consider it in the differential diagnosis of pediatric malignancies.
Medical Subject Headings
Adolescent; Carcinoma, Squamous Cell; Child; Child, Preschool; Cohort Studies; Combined Modality Therapy; Databases, Factual; Demography; Female; Head and Neck Neoplasms; Humans; Incidence; Infant; Male; Squamous Cell Carcinoma of Head and Neck; Survival Rate; Young Adult