Pediatric head and neck squamous cell carcinoma: Patient demographics, treatment trends and outcomes

Document Type


Publication Date


Publication Title

International journal of pediatric otorhinolaryngology


OBJECTIVES: To examine patient demographics, temporal and treatment trends, and survival outcomes of pediatric non-nasopharyngeal head and neck squamous cell carcinomas using the National Cancer Database.

METHODS: The National Cancer Database was queried for pediatric patients (age 0-19 years) diagnosed with squamous cell carcinoma of the head and neck (including oral cavity, oropharynx, nasal cavity, larynx, hypopharynx, and salivary glands) from 2004 to 2013.

RESULTS: Of 159 patients identified, the majority had oral cavity SCC (55%). There was no discernable change in incidence trends over the study period with the number of cases per year ranging from 10 to 20 (R

CONCLUSION: Although pediatric non-nasopharyngeal head and neck squamous cell carcinomas are rare, practitioners should be aware of this entity and consider it in the differential diagnosis of pediatric malignancies.

Medical Subject Headings

Adolescent; Carcinoma, Squamous Cell; Child; Child, Preschool; Cohort Studies; Combined Modality Therapy; Databases, Factual; Demography; Female; Head and Neck Neoplasms; Humans; Incidence; Infant; Male; Squamous Cell Carcinoma of Head and Neck; Survival Rate; Young Adult

PubMed ID




First Page


Last Page