Stereotactic Optimized Automated Radiotherapy (SOAR): a novel automated planning solution for multimetastatic SRS compared to HyperArc™

Document Type

Conference Proceeding

Publication Date

8-1-2022

Publication Title

Med Phys

Abstract

Purpose: Stereotactic Radiosurgery (SRS) planning for multi-metastatic patients is a complex process. The commercial HyperArc™ solution is limited to specific beam angles and immobilization. This study compares plan quality between the novel SOAR solution and HyperArc™. Methods: Twenty-five multi-metastatic SRS plans treated within the last 4 years were re-planned using SOAR and HyperArc™. Plans used the same number of isocenters and beam angles. SOAR used patient-specific characteristics, collision prediction, beam angle optimization, and automation with Eclipse Scripting to design and build treatment plans as described in our published works. Dose tuning structures, treatment fields, and optimization objectives were all added automatically. The automatic lower dose objective (ALDO) and SRS Normal Tissue Objective were used for HyperArc™ plans. All plans were normalized to have 100% or greater target coverage of all targets with the prescription isodose line. Multiple dose-volume metrics and SRS specific plan quality metrics were compared between HyperArc™ and automated plans using double-sided Wilcoxon signed-rank tests (α=0.05). Results: Differences in dose to the brainstem, cochlea, optic nerves and chiasm were statistically significant favoring SOAR. The median V12Gy volume was 14.2cc for automated planning and 11.7cc for HyperArc™ plans (p=0.4). The median conformity index was not found to be statistically different but median gradient index favored HyperArc™. Conclusion: The novel SOAR solution had better OAR sparing while maintaining similar target coverage to HyperArc™. SOAR is also able to simultaneously create multi-isocenter plans, is not limited to a specific immobilization device, and provides more freedom in beam angle selection.

Volume

49

Issue

8

First Page

5671

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