NASCI case of the month: "the role of FDG PET-CT in detecting active Takayasu arteritis"

Document Type

Article

Publication Date

7-19-2025

Publication Title

The international journal of cardiovascular imaging

Abstract

Takayasu arteritis (TA) is a chronic, granulomatous vasculitis which primarily affects large elastic arteries including the aorta and its major branches, leading to stenosis, occlusion, and aneurysm formation [de Souza et al. in Journal of Autoimmunity 48:79-83, 2014; Pelletier-Galarneau and Ruddy in Current Cardiology Reports 21(5), 2019, https://doi.org/10.1007/s11886-019-1122-z ]. Additional sequelae include heart failure secondary to hypertension, aortic regurgitation, and coronary artery involvement [Comarmond et al. in Circulation 136(12):1114-1122, 2017]. We describe the case of a young woman with progressive TA highlighting the role of fluorodeoxyglucose positron emission tomography-computed tomography (FDG-PET CT) in evaluating active inflammation. While FDG-PET CT can also be used to monitor response to treatment, this case demonstrates the utility of FDG-PET CT in evaluating active arteritis, allowing radiologists to help the clinician in guiding appropriate management.

PubMed ID

40682715

ePublication

ePub ahead of print

Volume

41

Issue

10

First Page

2061

Last Page

2063

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