Reversible splenial lesions presenting in conjunction with febrile illness: a case series and literature review.
Lin D, and Rheinboldt M. Reversible splenial lesions presenting in conjunction with febrile illness: a case series and literature review. Emerg Radiol 2017 Oct;24(5):599-604.
Transient restricted diffusion and increased T2 signal intensity within the splenium of the corpus callosum is an increasingly recognized albeit uncommon imaging feature in the setting of acute encephalitis and antecedent viral illness. This review will discuss three index cases obtained from an institutional databank. Additionally, the current understanding of the underlying neurophysiologic pathogenesis will be discussed together with differential clinical and imaging diagnostic considerations, treatment options, and outcome metrics.
Medical Subject Headings
Adolescent; Adult; Brain Diseases; Child; Contrast Media; Corpus Callosum; Diagnosis, Differential; Fever; Humans; Magnetic Resonance Imaging; Male; Tomography, X-Ray Computed; Virus Diseases