The use of normothermic liver preservation in combined liver and lung transplantation: A single-center experience

Document Type

Article

Publication Date

4-5-2022

Publication Title

American journal of transplantation

Abstract

Combined liver and lung transplantation (CLLT) is indicated in patients with both end-stage liver and lung disease. Ex-situ normothermic machine perfusion (NMP) has been previously used for extended normothermic lung preservation in CLLT. We aim to describe our single-center experience using ex-situ NMP for extended normothermic liver preservation in CLLT. Four CLLTs were performed from 2019 to 2020 with the lung transplanted first for all patients. Median ex-situ pump time for the liver was 413 min (IQR 400-424). Over a median follow-up of 15 months (IQR 14-19), all patients were alive and doing well. Normothermic extended liver preservation is a safe method to allow prolonged cold ischemia using normothermic perfusion of the liver during CLLT.

Medical Subject Headings

Transplant and Abdominal Surgery

PubMed ID

35384271

ePublication

ePub ahead of print

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