The use of normothermic liver preservation in combined liver and lung transplantation: A single-center experience

Authors

Tayseer M. Shamaa, Henry Ford HealthFollow
Omar Shamaa, Henry Ford HealthFollow
Catherine Crombez, Henry Ford HealthFollow
Jonathan M. Konel, Henry Ford HealthFollow
Toshihiro Kitajima, Henry Ford HealthFollow
Shingo Shimada, Henry Ford HealthFollow
Tommy Ivanics, Henry Ford HealthFollow
Adhnan Mohamed, Henry Ford HealthFollow
Kelly Collins, Henry Ford HealthFollow
Shunji Nagai, Henry Ford HealthFollow
Atsushi Yoshida, Henry Ford HealthFollow
Marwan S. Abouljoud, Henry Ford HealthFollow
Michael Rizzari, Henry Ford HealthFollow

Recommended Citation

Shamaa TM, Shamaa O, Crombez C, Konel JM, Kitajima T, Shimada S, Ivanics T, Mohamed A, Collins K, Nagai S, Yoshida A, Abouljoud M, and Rizzari M. The use of normothermic liver preservation in combined liver and lung transplantation: A single-center experience. Am J Transplant 2022.

Document Type

Article

Publication Date

4-5-2022

Publication Title

American journal of transplantation

Abstract

Combined liver and lung transplantation (CLLT) is indicated in patients with both end-stage liver and lung disease. Ex-situ normothermic machine perfusion (NMP) has been previously used for extended normothermic lung preservation in CLLT. We aim to describe our single-center experience using ex-situ NMP for extended normothermic liver preservation in CLLT. Four CLLTs were performed from 2019 to 2020 with the lung transplanted first for all patients. Median ex-situ pump time for the liver was 413 min (IQR 400-424). Over a median follow-up of 15 months (IQR 14-19), all patients were alive and doing well. Normothermic extended liver preservation is a safe method to allow prolonged cold ischemia using normothermic perfusion of the liver during CLLT.

Medical Subject Headings

Transplant and Abdominal Surgery

PubMed ID

35384271

ePublication

ePub ahead of print