The use of normothermic liver preservation in combined liver and lung transplantation: A single-center experience
Recommended Citation
Shamaa TM, Shamaa O, Crombez C, Konel JM, Kitajima T, Shimada S, Ivanics T, Mohamed A, Collins K, Nagai S, Yoshida A, Abouljoud M, and Rizzari M. The use of normothermic liver preservation in combined liver and lung transplantation: A single-center experience. Am J Transplant 2022.
Document Type
Article
Publication Date
4-5-2022
Publication Title
American journal of transplantation
Abstract
Combined liver and lung transplantation (CLLT) is indicated in patients with both end-stage liver and lung disease. Ex-situ normothermic machine perfusion (NMP) has been previously used for extended normothermic lung preservation in CLLT. We aim to describe our single-center experience using ex-situ NMP for extended normothermic liver preservation in CLLT. Four CLLTs were performed from 2019 to 2020 with the lung transplanted first for all patients. Median ex-situ pump time for the liver was 413 min (IQR 400-424). Over a median follow-up of 15 months (IQR 14-19), all patients were alive and doing well. Normothermic extended liver preservation is a safe method to allow prolonged cold ischemia using normothermic perfusion of the liver during CLLT.
Medical Subject Headings
Cold Ischemia; Humans; Liver/surgery; Lung Transplantation; Organ Preservation/methods; Perfusion/methods; artificial organs; clinical research; donors and donation: deceased; hepatology; liver disease; liver transplantation; lung disease; lung transplantation; organ perfusion and preservation; organ procurement and allocation; practice; pulmonology; support devices
PubMed ID
35384271
ePublication
ePub ahead of print
Volume
22
Issue
9
First Page
2261
Last Page
2264
