Outcome of African American (AA) compared to white American (WA) patients with early-stage breast cancer, stratified by phenotype

Document Type

Conference Proceeding

Publication Date

2018

Publication Title

Ann Surg Oncol

Abstract

INTRODUCTION: Population-based breast cancer mortality rates are approximately 40% higher for AA compared to WA women. The extent to which these outcome disparities are related to the two-fold higher incidence of triple negative breast cancer (TNBC) in AAs is unclear. Methods: We evaluated survival among AA and WA pts presenting with clinically early-stage/node negative breast cancer, stratified by having TNBC versus non-TNBC phenotype from a prospectively-maintained, IRB-approved database in an employee health plan-based hospital system serving a diverse community; Median follow-up was 60 months. Results: A total of 2,847 cases were analyzed; 1,061 (37%) AA and 1,786 (63%) WA. Frequency of TNBC was higher among the AA patients compared to WA patients (15% versus 10%; p

Volume

25

Issue

1 Suppl

First Page

S87

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