Outcome of African American (AA) compared to white American (WA) patients with early-stage breast cancer, stratified by phenotype
Lehrberg A, Nathanson D, Baidoun F, Petersen L, Susick L, Davis M, Ivanics T, Rakitin I, Bensenhaver J, Proctor E, and Newman L. Outcome of African American (AA) compared to white American (WA) patients with early-stage breast cancer, stratified by phenotype. Ann Surg Oncol 2018; 25(1 Suppl):S87.
Ann Surg Oncol
INTRODUCTION: Population-based breast cancer mortality rates are approximately 40% higher for AA compared to WA women. The extent to which these outcome disparities are related to the two-fold higher incidence of triple negative breast cancer (TNBC) in AAs is unclear. Methods: We evaluated survival among AA and WA pts presenting with clinically early-stage/node negative breast cancer, stratified by having TNBC versus non-TNBC phenotype from a prospectively-maintained, IRB-approved database in an employee health plan-based hospital system serving a diverse community; Median follow-up was 60 months. Results: A total of 2,847 cases were analyzed; 1,061 (37%) AA and 1,786 (63%) WA. Frequency of TNBC was higher among the AA patients compared to WA patients (15% versus 10%; p