Impact of national comprehensive cancer network (NCCN) genetic testing guidelines on genetic counseling referral patterns for triple negative breast cancer (TNBC) patients

Authors

Ilya Rakitin, Henry Ford HealthFollow
M Quigg, Henry Ford Health
Mary Nyhuis, Henry Ford HealthFollow
Lindsay Petersen, Henry Ford HealthFollow
S David Nathanson, Henry Ford HealthFollow
Melissa B. Davis, Henry Ford HealthFollow
Laura Susick, Henry Ford HealthFollow
Erica Proctor, Henry Ford HealthFollow
Jessica Bensenhaver, Henry Ford HealthFollow
Lisa A. Newman, Henry Ford HealthFollow

Recommended Citation

Rakitin I, Quigg M, Nyhuis M, Petersen L, Nathanson D, Davis M, Susick L, Proctor E, Bensenhaver J, and Newman L. Impact of national comprehensive cancer network (NCCN) genetic testing guidelines on genetic counseling referral patterns for triple negative breast cancer (TNBC) patients. Ann Surg Oncol 2018; 25(1 Suppl):S43.

Document Type

Conference Proceeding

Publication Date

2018

Publication Title

Ann Surg Oncol

Abstract

INTRODUCTION: In 2011 the NCCN revised the clinical practice guideline regarding identification of breast cancer pts that should be referred for genetic counseling/testing, to include any woman diagnosed with triple negative breast cancer (TNBC) ≤60 years, regardless of family history. Little is known regarding the impact of this revision on referral patterns and testing results among African American (AA) women, who face an increased risk of TNBC compared to White Americans (WAs). Methods: We queried a prospectively-maintained, IRB-approved breast cancer database linked to a genetic counseling program in a diverse metropolitan multi-hospital health system. Genetic counseling referrals prior to 2011 versus after 2011 were evaluated and stratified by AA versus WA. Results: Of 2984 pts with invasive breast cancer (57% WA; 32% AA) seen 05/1997 to 01/2017, 12% had TNBC. Frequency of TNBC was 16% for AA and 10% for WA pts (p

Volume

25

Issue

1 Suppl

First Page

S43