Incidence trends among deceased liver transplant recipients in the United States, 2011-2016: A propensity score-matched study
Recommended Citation
Schilke R, Safwan M, Collins K, Rizzari M, Yoshida A, Abouljoud M, and Nagai S. Incidence trends among deceased liver transplant recipients in the United States, 2011-2016: A propensity score-matched study. Am J Transplant 2018;18(Suppl 4):564.
Document Type
Conference Proceeding
Publication Date
2018
Publication Title
Am J Transplant
Abstract
Background Donation after cardiac death (DCD) donor liver graft is a known risk factor for graft failure secondary to primary non-function (PNF) and/or diffuse cholangiopathy (DC). We aimed to study mortality and graft failure hazard ratio trends among DCD vs. donation after brain death (DBD) recipients. Methods Retrospective data of adult recipients ≥18 years from the national United Network for Organ Sharing registry 2011-2016 were analyzed. Clinically significant donor, recipient, and operative characteristics were balanced among donor groups using propensity score-matching (PSM). All-cause mortality, all-cause graft failure, graft failure due to DC and PNF were estimated using Cox proportional hazards models. Results Among a total of 29573 recipients, 1800 (6.09%) received DCD livers. Overall, PSM DCD recipients should expect worse 2-year all-cause mortality, 2-year allcause graft failure, 2-year graft failure due to DC, and 1-year graft failure due to PNF in comparison to DBD recipients (HR=1.43, 1.45, 5.24, and 3.08, respectively). PSM all-cause mortality and all-cause graft failure incidence for both DCD and DBD recipients indicate declining trends (P
Volume
18
Issue
Suppl 4
First Page
564
