Necrotizing granulomatous epididymo-orchitis post intravesical BCG administration after brachytherapy for prostate cancer

Authors

Jay K. Jhaveri, Henry Ford Health
Aaron Dahmen
Alon Lazarovich
David Nusbaum
Quoc-Dien Trinh
Nilesh S. Gupta, Henry Ford HealthFollow
Piyush K. Agarwal

Recommended Citation

Jhaveri JK, Dahmen A, Lazarovich A, Nusbaum D, Trinh QD, Gupta N, and Agarwal PK. Necrotizing granulomatous epididymo-orchitis post intravesical BCG administration after brachytherapy for prostate cancer. Urol Case Rep 2024; 54:102694.

Document Type

Article

Publication Date

5-1-2024

Publication Title

Urol Case Rep

Abstract

Urothelial carcinoma of the bladder remains a challenging disease to treat. Intravesical instillation of BCG has demonstrated tremendous efficacy in preventing recurrence. BCG related necrotizing granulomatous epididymo-orchitis is rare and has not been previously linked to brachytherapy for adenocarcinoma of the prostate. We hypothesize that prior brachytherapy has a deleterious effect on the verumontanum that can result in retrograde transmission of BCG particles leading to granulomatous epididymo-orchitis. This is the first case report of necrotizing granulomatous epididymo-orchitis related to BCG in a patient status post brachytherapy for adenocarcinoma of the prostate.

PubMed ID

38516176

Volume

54

First Page

102694

Last Page

102694