Maternal-Cord Blood Vitamin D Correlations Vary by Maternal Levels

Document Type

Article

Publication Date

1-1-2016

Publication Title

J Pregnancy

Abstract

Vitamin D levels of pregnant women and their neonates tend to be related; however, it is unknown whether there are any subgroups in which they are not related. 25-Hydroxyvitamin D [25(OH)D] was measured in prenatal maternal and child cord blood samples of participants (n = 241 pairs) in a birth cohort. Spearman correlations were examined within subgroups defined by prenatal and delivery factors. Cord blood as a percentage of prenatal 25(OH)D level was calculated and characteristics compared between those who did and did not have ≥25% and ≥50% of the maternal level and those who did and did not have a detectable 25(OH)D level. The correlation among Black children was lower than in White children. When the maternal 25(OH)D level was/mL, the overall correlation was r = 0.16. Most children had a 25(OH)D cord blood level less than half of their mother's; 15.4% had a level that was

Medical Subject Headings

Adult; African Americans; Cholecalciferol; Cohort Studies; Ergocalciferols; European Continental Ancestry Group; Female; Fetal Blood; Humans; Michigan; Obesity; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Seasons; Vitamin D; Vitamin D Deficiency; Young Adult

PubMed ID

27066272

Volume

2016

First Page

7474192

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