EE238 Eosinophilic Esophagitis-Related Healthcare Resource Utilization: A Retrospective Cohort Study of US Health Insurance Claims Data
Recommended Citation
Gold BD, Jensen ET, Goodwin B, Liu E, Kim M, Schwartz TT, Schaeffer-Koziol CR, Terreri B, Baptist AP. EE238 Eosinophilic Esophagitis-Related Healthcare Resource Utilization: A Retrospective Cohort Study of US Health Insurance Claims Data. Value Health 2025; 28(6):S106.
Document Type
Conference Proceeding
Publication Date
7-1-2025
Publication Title
Value Health
Abstract
Objectives: To assess eosinophilic esophagitis (EoE)-related healthcare resource utilization (HCRU) among patients in the USA. Methods: This retrospective, longitudinal cohort study analyzedUShealth insurance data from the Inovalon closed claims (ICC) database and the 100% sample of MedicareFee-For-Service (MFFS) parts A/B/D claims and enrollment data (January 1, 2016-December 31, 2022). Eligible patients (≥11 years old) had ≥2 claims (≥30 days apart) for EoE in the index period (January 1, 2017-December 31, 2021 [index date=date of first claim for EoE]) and had continuous enrollment in medical and pharmacy benefits for ≥12 months before and after their index date (baseline and follow-up, respectively). Patients with a post-index diagnosis of eosinophilic gastritis/gastroenteritis were excluded. EoE-related hospitalizations and emergency department (ED), outpatient and post-acute care visits were assessed. Results: Data from 37,809 and 15,109 patients (ICC and MFFS, respectively) were analyzed. Mean (standard deviation) ages of patients (ICC and MFFS) were 38.1 (16.7) and 66.8 (13.2) years, respectively; >50% of patients were male (ICC and MFFS) and 90.3% were White (MFFS only). During 12-months of follow-up, EoE-related HCRU (proportion of patients with ≥1 visit and mean [standard error] number of visits/patient/month) from ICC was: hospitalizations, 1.6% and 0.02 (0.17); ED, 3.7% and 0.04 (0.24); ED-food impactions, 1.5% and 0.02 (0.13); outpatient physician office, 98.1% and 3.00 (4.40); and any other outpatient, 42.0% and 0.69 (1.12). Corresponding MFFS data were: hospitalizations, 2.7% and 0.03 (0.22); ED, 2.3% and 0.03 (0.18); ED-food impactions, 1.0% and 0.01 (0.10); outpatient physician office, 95.6% and 3.12 (2.53); and any other outpatient, 32.3% and 0.56 (1.08). Proportions of patients with ≥1 visit for post-acute care were ≤0.7% (ICC and MFFS). Conclusions: EoE represents a substantial healthcare burden in adolescents and adults in the USA, driven by frequent outpatient visits; food impactions were a leading cause of ED admissions.
Volume
28
Issue
6
First Page
S106
