Neurologic Complications after Transcatheter Aortic Valve Replacement: An Updated Review of Incidence, Current Treatments, and Future Directions.
Recommended Citation
Patel R, Andrews T, Frisoli TM. Neurologic Complications after Transcatheter Aortic Valve Replacement. Interven Cardiol Clin. 2026;15(4):535-547.
Document Type
Article
Publication Date
10-1-2026
Publication Title
Interv Cardiol Clin
Keywords
Humans, Transcatheter Aortic Valve Replacement, Aortic Valve Stenosis, Incidence, Stroke, Postoperative Complications, Risk Factors, Left Atrial Appendage Closure
Abstract
Transcatheter aortic valve replacement (TAVR) is the standard treatment for severe aortic stenosis, yet stroke remains a persistent complication with significant morbidity. This review summarizes the incidence, timing, mechanisms, and predictors of TAVR-related stroke, highlighting procedural embolization and patient comorbidities. We examine evidence for cerebral embolic protection devices, pharmacologic strategies, and left atrial appendage closure in mitigating risk. Despite advances in technology, randomized trials have not shown consistent stroke reduction with embolic protection. Optimal prevention requires individualized strategies balancing thromboembolic and bleeding risks across acute, subacute, and late post-TAVR periods.
Medical Subject Headings
Humans; Transcatheter Aortic Valve Replacement; Aortic Valve Stenosis; Incidence; Stroke; Postoperative Complications; Risk Factors; Left Atrial Appendage Closure
PubMed ID
42648858
Volume
15
Issue
4
First Page
535
Last Page
547
