Neurologic Complications after Transcatheter Aortic Valve Replacement: An Updated Review of Incidence, Current Treatments, and Future Directions

Document Type

Article

Publication Date

10-1-2026

Publication Title

Interv Cardiol Clin

Keywords

Humans, Transcatheter Aortic Valve Replacement, Aortic Valve Stenosis, Incidence, Stroke, Postoperative Complications, Risk Factors, Left Atrial Appendage Closure

Abstract

Transcatheter aortic valve replacement (TAVR) is the standard treatment for severe aortic stenosis, yet stroke remains a persistent complication with significant morbidity. This review summarizes the incidence, timing, mechanisms, and predictors of TAVR-related stroke, highlighting procedural embolization and patient comorbidities. We examine evidence for cerebral embolic protection devices, pharmacologic strategies, and left atrial appendage closure in mitigating risk. Despite advances in technology, randomized trials have not shown consistent stroke reduction with embolic protection. Optimal prevention requires individualized strategies balancing thromboembolic and bleeding risks across acute, subacute, and late post-TAVR periods.

Medical Subject Headings

Humans; Transcatheter Aortic Valve Replacement; Aortic Valve Stenosis; Incidence; Stroke; Postoperative Complications; Risk Factors; Left Atrial Appendage Closure

PubMed ID

42648858

Volume

15

Issue

4

First Page

535

Last Page

547

Find It @ Sladen

Share

COinS