18 F-FDG PET and MRI Evaluation of Paraneoplastic Limbic Encephalitis

Document Type

Article

Publication Date

7-1-2023

Publication Title

Clinical nuclear medicine

Abstract

Autoimmune limbic encephalitis (paraneoplastic or nonparaneoplastic) is a rare condition involving autoantibodies against intracellular or cell-surface proteins of neurons. Patients typically present with acute and progressive neuropsychiatric symptoms. Although the criterion standard for diagnosis remains detection of autoantibodies in cerebrospinal fluid, there are characteristic imaging features that can aid in diagnosis, notably abnormalities in the bilateral medial temporal lobes on imaging, particularly with nuclear imaging. Here, we present 18 F-FDG PET findings of paraneoplastic limbic encephalitis in a 65-year-old man.

Medical Subject Headings

Male; Humans; Aged; Limbic Encephalitis; Fluorodeoxyglucose F18; Magnetic Resonance Imaging; Autoantibodies; Autoimmune Diseases

PubMed ID

37167219

ePublication

ePub ahead of print

Volume

48

Issue

7

First Page

617

Last Page

619

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