Dedifferentiated endometrial carcinoma metastasis to axillary lymph node: a case report

Authors

Chase William Morrison
Kayvon Nick Sanjasaz
Saul David Nathanson, Henry Ford HealthFollow
Supriya Raina-Hukku, Henry Ford HealthFollow
David M. Pinkney, Henry Ford HealthFollow
Alexis A. Davenport, Henry Ford HealthFollow

Recommended Citation

Morrison CW, Sanjasaz KN, Nathanson SD, Raina-Hukku S, Pinkney DM, and Davenport AA. Dedifferentiated endometrial carcinoma metastasis to axillary lymph node: a case report. J Med Case Rep 2023; 17(1):451.

Document Type

Article

Publication Date

10-30-2023

Publication Title

J Med Case Rep

Abstract

BACKGROUND: We present an unusual case of a left axillary lymph node metastasis from a primary dedifferentiated endometrial carcinoma. This pattern of metastasis is likely the result of circulating tumor cells reaching the node through its arterial blood supply.

CASE PRESENTATION: In this report, a 68-year-old white woman with a dedifferentiated endometrial carcinoma underwent a hysterectomy. She later developed an enlarged axillary lymph node due to metastatic dedifferentiated endometrial carcinoma, treated with chemotherapy and anti-programmed cell death protein 1 immunotherapy resulting in a complete clinical and radiological response.

CONCLUSION: A review of the literature reveals the rarity of blood-borne lymph node metastasis, especially with uterine carcinoma. Immunotherapy has shown promising results in the treatment of some subtypes of metastatic uterine carcinoma.

Medical Subject Headings

Female; Humans; Aged; Lymphatic Metastasis; Lymph Nodes; Carcinoma; Endometrial Neoplasms; Hysterectomy

PubMed ID

37899461

Volume

17

Issue

1

First Page

451

Last Page

451