Scholarly journal articles authored by members of the Department of Neurosurgery at Henry Ford Health.

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Submissions from 2017

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An extended vascular model for less biased estimation of permeability parameters in DCE-T1 images, Siamak P. Nejad-Davarani, Hassan Bagher-Ebadian, James R. Ewing, Douglas C. Noll, Tom Mikkelsen, Michael Chopp, and Quan Jiang

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A parametric model of the brain vascular system for estimation of the arterial input function (AIF) at the tissue level, Siamak P. Nejad-Davarani, Hassan Bagher-Ebadian, James R. Ewing, Douglas C. Noll, Tom Mikkelsen, Michael Chopp, and Quan Jiang

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A case of symptomatic spinal dural arteriovenous fistula after high-volume lumbar puncture, Thomas Noh, Rahul Chandra, Jimmy Kim, and Ian Lee

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Management of acute subdural hematoma in a patient with portopulmonary hypertension on prostanoid therapy, Richard Rammo, Adam Robin, Jessin John, Aqueel Pabaney, Panayiotis N. Varelas, and Maximillian K. Kole

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Comment: Is virtual reality a useful adjunct to rehabilitation after spinal cord injury?, Richard Rammo and Jason M. Schwalb

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Racial disparities in the diagnosis and management of trigeminal neuralgia, Kevin Reinard, David R. Nerenz, Azam Basheer, Rizwan A. Tahir, Timothy Jelsema, Lonni Schultz, Ghaus Malik, Ellen L. Air, and Jason M. Schwalb

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Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles, Agnes T. Reiner, Kenneth W. Witwer, Bas WM van Balkom, Joel de Beer, Chaya Brodie, Randolph L. Corteling, Susanne Gabrielsson, Mario Gimona, Ahmed G. Ibrahim, Dominique de Kleijn, Charles P. Lai, Jan Lötvall, Hernando A. Del Portillo, Ilona G. Reischl, Milad Riazifar, Carlos Salomon, Hidetoshi Tahara, Wei-Seong Toh, Marca HM Wauben, Vicky K. Yang, Yijun Yang, Ronne WY Yeo, Hang Yin, Bernd Giebel, Eva Rohde, and Sai-Kiang Lim

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Reoperation for Recurrent Glioblastoma Multiforme, Adam M. Robin, Ian Lee, and Steven N. Kalkanis

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Therapeutic Effect of Astroglia-like Mesenchymal Stem Cells Expressing Glutamate Transporter in a Genetic Rat Model of Depression, Amit Shwartz, Oshra Betzer, Noam Kronfeld, Gila Kazimirsky, Simona Cazacu, Susan Finniss, Hae-Kyung Lee, Menachem Motiei, Shani Y. Dagan, Rachela Popovtzer, Chaya Brodie, and Gal Yadid

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Multimodal Imaging in a Patient with Hemidystonia Responsive to GPi Deep Brain Stimulation, Christos Sidiropoulos, Susan M. Bowyer, Andrew Zillgitt, Peter A. LeWitt, Hassan Bagher-Ebadian, Esmaeil Davoodi-Bojd, Jason M. Schwalb, Richard Rammo, Ellen L. Air, and Hamid Soltanian-Zadeh

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Predicting symptomatic cerebral vasospasm after aneurysmal subarachnoid hemorrhage with an artificial neural network in a pediatric population, Jesse Skoch, Rizwan A. Tahir, Todd Abruzzo, John M. Taylor, Mario Zuccarello, and Sudhakar Vadivelu

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The role of tumor board conferences in neuro-oncology: a nationwide provider survey, James Snyder, Lonni Schultz, and Tobias Walbert

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Separate origins of the left internal and external carotid arteries from the aortic arch and cervical internal carotid artery aneurysm in a patient with Noonan syndrome, Rizwan A. Tahir, Karam Asmaro, Aqueel Pabaney, Maximillian K. Kole, Timothy Nypaver, and Horia Marin

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Complication rates associated with open versus percutaneous pedicle screw instrumentation among patients undergoing minimally invasive interbody fusion for adult spinal deformity, Khoi D. Than, Praveen V. Mummaneni, Kelly J. Bridges, Stacie Tran, Paul Park, Dean Chou, Frank LaMarca, Juan S. Uribe, Todd D. Vogel, Pierce D. Nunley, Robert K. Eastlack, Neel Anand, David O. Okonkwo, Adam S. Kanter, and Gregory M. Mundis

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Efficacy of depatuxizumab mafodotin (ABT-414) monotherapy in patients with EGFR-amplified, recurrent glioblastoma: results from a multi-center, international study, Martin van den Bent, Hui K. Gan, Andrew B. Lassman, Priya Kumthekar, Ryan Merrell, Nicholas Butowski, Zarnie Lwin, Tom Mikkelsen, Louis B. Nabors, Kyriakos P. Papadopoulos, Marta Penas-Prado, John Simes, Helen Wheeler, Tobias Walbert, Andrew M. Scott, Erica Gomez, Ho-Jin Lee, Lisa Roberts-Rapp, Hao Xiong, Earle Bain, Peter J. Ansell, Kyle D. Holen, David Maag, and David A. Reardon

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Palliative Care, End-of-Life Care, and Advance Care Planning in Neuro-oncology, Tobias Walbert

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Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment, Qianghu Wang, Baoli Hu, Xin Hu, Hoon Kim, Massimo Squatrito, Lisa Scarpace, Ana C. de Carvalho, Sali Lyu, Pengping Li, Yan Li, Floris Barthel, Hee-Jin Cho, Yu-Hsi Lin, Nikunj Satani, Emmanuel Martinez-Ledesma, Siyuan Zheng, Edward Chang, Charles-Etienneabriel G. Sauvé, Adriana Olar, Zheng D. Lan, Gaetano Finocchiaro, Joanna J. Phillips, Mitchel S. Berger, Konrad R. Gabrusiewicz, Guocan Wang, Eskil Eskilsson, Jian Hu, Tom Mikkelsen, Ronald A. DePinho, Florian Muller, Amy B. Heimberger, Erik P. Sulman, Do-Hyun Nam, and Roel G W Verhaak

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Thalamic DBS with a constant-current device in essential tremor: A controlled clinical trial, Robert E. Wharen, Michael S. Okun, Barton L. Guthrie, Ryan J. Uitti, Paul Larson, Kelly Foote, Harrison Walker, Frederick J. Marshall, Jason M. Schwalb, Blair Ford, Joseph Jankovic, Richard Simpson, Khashayar Dashtipour, Fenna Phibbs, Joseph S. Neimat, R M. Stewart, DeLea Peichel, Rajesh Pahwa, and Jill L. Ostrem

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Emerging potential of exosomes for treatment of traumatic brain injury, Ye Xiong, Asim Mahmood, and Michael Chopp

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Automated Whole Brain Tractography Affects Preoperative Surgical Decision Making, Hesham M. Zakaria, Sameah A. Haider, and Ian Lee

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Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves functional recovery in rats after traumatic brain injury, Yanlu Zhang, Michael Chopp, Zhenggang Zhang, Mark Katakowski, Hongqi Xin, Changsheng Qu, Meser M. Ali, Asim Mahmood, and Ye Xiong

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Treatment of traumatic brain injury in rats with N-acetyl-seryl-aspartyl-lysyl-proline, Yanlu Zhang, Zhenggang Zhang, Michael Chopp, Yuling Meng, Li Zhang, Asim Mahmood, and Ye Xiong

Submissions from 2016

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Presenting signs and symptoms in brain tumors, Agusti Alentorn, Khê Hoang-Xuan, and Tom Mikkelsen

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MRI Pre- and Post-Embolization Enhancement Patterns Predict Surgical Outcomes in Intracranial Meningiomas, Rushna Ali, Muhib Khan, Victor Chang, Jayant Narang, Rajan Jain, Horia Marin, Jack Rock, and Maximillian K. Kole

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Use of the modified frailty index to predict 30-day morbidity and mortality from spine surgery, Rushna Ali, Jason M. Schwalb, David R. Nerenz, Heath J. Antoine, and Ilan Rubinfeld

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Shining light on neurosurgery diagnostics using Raman spectroscopy, Brandy Broadbent, James Tseng, Rachel Kast, Thomas Noh, Michelle Brusatori, Steven N. Kalkanis, and Gregory W. Auner

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Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells, Monica E. Burgett, Justin D. Lathia, Patrick Roth, Amy S. Nowacki, Deni S. Galileo, Elena Pugacheva, Ping Huang, Amit Vasanji, Meizhang Li, Tatiana Byzova, Tom Mikkelsen, Shideng Bao, Jeremy N. Rich, Michael Weller, and Candece L. Gladson

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Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma, Michele Ceccarelli, Floris P. Barthel, Tathiane M. Malta, Thais S. Sabedot, Sofie R. Salama, Bradley A. Murray, Olena Morozova, Yulia Newton, Amie Radenbaugh, Stefano M. Pagnotta, Samreen Anjum, Jiguang Wang, Ganiraju Manyam, Pietro Zoppoli, Shiyun Ling, Arjun A. Rao, Mia Grifford, Andrew D. Cherniack, Hailei Zhang, Laila M. Poisson, Carlos G. Carlotti, Daniela Tirapelli, Arvind Rao, Tom Mikkelsen, Ching C. Lau, W KA Yung, Raul Rabadan, Jason Huse, Daniel J. Brat, Norman L. Lehman, Jill S. Barnholtz-Sloan, Siyuan Zheng, Kenneth Hess, Ganesh Rao, Matthew Meyerson, Rameen Beroukhim, Lee Cooper, Rehan Akbani, Margaret Wrensch, David Haussler, Kenneth D Aldape, Peter W Laird, David H Gutmann, Houtan Noushmehr, Antonio Iavarone, and Roel G W Verhaak

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Phase 1 trial of vocimagene amiretrorepvec and 5-fluorocytosine for recurrent high-grade glioma, Timothy F. Cloughesy, Joseph Landolfi, Daniel J. Hogan, Stephen Bloomfield, Bob Carter, Clark C. Chen, J B. Elder, Steven N. Kalkanis, Santosh Kesari, Albert Lai, Ian Lee, Linda M. Liau, Tom Mikkelsen, Phioanh L. Nghiemphu, David Piccioni, Tobias Walbert, Alice Chu, Asha Das, Oscar R. Diago, Dawn Gammon, Harry E. Gruber, Michelle Hanna, Douglas J. Jolly, Noriyuki Kasahara, David McCarthy, Leah Mitchell, Derek Ostertag, Joan M. Robbins, Maria Rodriguez-Aguirre, and Michael A. Vogelbaum

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Prioritization schema for immunotherapy clinical trials in glioblastoma, Tiffany R. Hodges, Sherise D. Ferguson, Hillary G. Caruso, Gary Kohanbash, Shouhao Zhou, Timothy F. Cloughesy, Mitchel S. Berger, George H. Poste, Mustafa Khasraw, Sujuan Ba, Tao Jiang, Tom Mikkelsen, W KA Yung, John F. de Groot, Howard Fine, Lewis C. Cantley, Ingo K. Mellinghoff, Duane A. Mitchell, Hideho Okada, and Amy B. Heimberger

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Serum proteins are extracted along with monolayer cells in plasticware and interfere with protein analysis, Xin Hong, Yuling Meng, and Steven N. Kalkanis

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Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma, Wei Jiang, Susan Finniss, Simona Cazacu, Cunli Xiang, Ziv Brodie, Tom Mikkelsen, Laila M. Poisson, David B. Shackelford, and Chaya Brodie

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Mesenchymal stem cells enhance the oncolytic effect of Newcastle disease virus in glioma cells and glioma stem cells via the secretion of TRAIL, Gila Kazimirsky, Wei Jiang, Shimon Slavin, Amotz Ziv-Av, and Chaya Brodie

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A Prospective Safety Trial of Atorvastatin Treatment to Assess Rebleeding after Spontaneous Intracerebral Hemorrhage: A Serial MRI Investigation, Robert A. Knight, Tavarekere N. Nagaraja, Lian Li, Quan Jiang, Kelly M. Tundo, Michael Chopp, and Donald Seyfried

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Stereotactic Laser Interstitial Thermal Therapy for Recurrent High-Grade Gliomas, Ian Lee, Steven N. Kalkanis, and Constantinos G. Hadjipanayis

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Circle of Willis Collateral During Temporary Internal Carotid Artery Occlusion I: Observations From Digital Subtraction Angiography, Stephen P. Lownie, Ramiro Larrazabal, and Maximillian K. Kole

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Literature review of vaccine-related adverse events reported from HPV vaccination in randomized controlled trials, Mohamed Macki and Ali A. Dabaja

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rhBMP-2 protects against reoperation for pseudoarthrosis and/or instrumentation failure: A matched case-control study of 448 patients, Mohamed Macki, Sbaa Syeda, Panagiotis Kerezoudis, Ali Bydon, Timothy F. Witham, Daniel M. Sciubba, Jean-Paul Wolinsky, Mohamad Bydon, and Ziya Gokaslan

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Preoperative motor strength and time to surgery are the most important predictors of improvement in foot drop due to degenerative lumbar disease, Mohamed Macki, Sbaa Syeda, Panagiotis Kerezoudis, Ziya L. Gokaslan, Ali Bydon, and Mohamad Bydon

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Long-term Arrhythmia Monitoring in Cryptogenic Stroke: Who, How, and for How Long?, Mayra Montalvo, Rushna Ali, Brian Silver, and Muhib Khan

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DTI-based response-driven modeling of mTLE laterality, Mohammad-Reza Nazem-Zadeh, Kost Elisevich, Ellen L. Air, Jason M. Schwalb, George Divine, Manpreet Kaur, Vibhangini S. Wasade, Fariborz Mahmoudi, Saeed Shokri, Hassan Bagher-Ebadian, and Hamid Soltanian-Zadeh

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A novel technique to repair a transverse sacral fracture in a previously fused lumbosacral spondylolisthesis, Thomas Noh and Mokbel Chedid

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Arteriovenous malformations of the corpus callosum: Pooled analysis and systematic review of literature, Aqueel H. Pabaney, Rushna Ali, Maximillian K. Kole, and Ghaus Malik

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Development of De Novo Arteriovenous Malformation Following Ischemic Stroke: Case Report and Review of Current Literature, Aqueel H. Pabaney, Richard A. Rammo, Rizwan A. Tahir, and Donald Seyfried

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Management of arteriovenous malformations in the elderly: a single-center case series and analysis of outcomes, Aqueel H. Pabaney, Kevin A. Reinard, Maximillian K. Kole, Donald Seyfried, and Ghaus Malik

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Surgical Management of Dural Arteriovenous Fistula After Craniotomy: Case Report and Review of Literature, Aqueel H. Pabaney, Adam Robin, Azam Basheer, and Ghaus Malik

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Preferential expression of functional IL-17R in glioma stem cells: potential role in self-renewal, Prahlad Parajuli, Rohit Anand, Chandramouli Mandalaparty, Raviteja Suryadevara, Preethi U. Sriranga, Sharon K. Michelhaugh, Simona Cazacu, Susan Finniss, Archana Thakur, Lawrence G. Lum, Dana Schalk, Chaya Brodie, and Sandeep Mittal

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Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis, Vijay Ramaswamy, Thomas Hielscher, Stephen C. Mack, Alvaro Lassaletta, Tong Lin, Kristian W. Pajtler, David TW Jones, Betty Luu, Florence MG Cavalli, Kenneth Aldape, Marc Remke, Martin Mynarek, Stefan Rutkowski, Sridharan Gururangan, Roger E. McLendon, Eric S. Lipp, Christopher Dunham, Juliette Hukin, David D. Eisenstat, Dorcas Fulton, Frank KH van Landeghem, Mariarita Santi, Marie-Lise C. van Veelen, Erwin G. Van Meir, Satoru Osuka, Xing Fan, Karin M. Muraszko, Daniela PC Tirapelli, Sueli M. Oba-Shinjo, Suely KN Marie, Carlos G. Carlotti, Ji-Yeoun Lee, Amulya A Nageswara Rao, Caterina Giannini, Claudia C Faria, Sofia Nunes, Jaume Mora, Ronald L Hamilton, Peter Hauser, Nada Jabado, Kevin Petrecca, Shin Jung, Luca Massimi, Massimo Zollo, Giuseppe Cinalli, László Bognár, Almos Klekner, Tibor Hortobágyi, Sarah Leary, Ralph P Ermoian, James M Olson, Jeffrey R Leonard, Corrine Gardner, Wieslawa A Grajkowska, Lola B Chambless, Jason Cain, Charles G Eberhart, Sama Ahsan, Maura Massimino, Felice Giangaspero, Francesca R Buttarelli, Roger J Packer, Lyndsey Emery, William H Yong, Horacio Soto, Linda M Liau, Richard Everson, Andrew Grossbach, Tarek Shalaby, Michael Grotzer, Matthias A Karajannis, David Zagzag, Helen Wheeler, Katja von Hoff, Marta M Alonso, Teresa Tuñon, Ulrich Schüller, Karel Zitterbart, Jaroslav Sterba, Jennifer A Chan, Miguel Guzman, Samer K Elbabaa, Howard Colman, Girish Dhall, Paul G Fisher, Maryam Fouladi, Amar Gajjar, Stewart Goldman, Eugene Hwang, Marcel Kool, Harshad Ladha, Elizabeth Vera-Bolanos, Khalida Wani, Frank Lieberman, Tom Mikkelsen, Antonio M Omuro, Ian F Pollack, Michael Prados, H Ian Robins, Riccardo Soffietti, Jing Wu, Phillipe Metellus, Uri Tabori, Ute Bartels, Eric Bouffet, Cynthia E Hawkins, James T Rutka, Peter Dirks, Stefan M Pfister, Thomas E Merchant, Mark R Gilbert, Terri S Armstrong, Andrey Korshunov, David W Ellison, and Michael D Taylor

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Anaplastic meningioma: octreotide therapy for a case of recurrent and progressive intracranial disease, Richard Rammo, Adam Rock, Andrea D. Transou, Aditya Raghunathan, and Jack Rock

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A cohort study of the morbidity of combined anterior-posterior cervical spinal fusions: incidence and predictors of postoperative dysphagia, Kevin A. Reinard, Diana M. Cook, Hesham M. Zakaria, Azam Basheer, Victor Chang, and Muwaffak M. Abdulhak

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Preoperative external tissue expansion for complex cranial reconstructions, Kevin A. Reinard, Hesham M. Zakaria, Ahmad Qatanani, Ian Lee, Jack P. Rock, and Herman P. Houin

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Phase 1 dose escalation trial of the safety and pharmacokinetics of cabozantinib concurrent with temozolomide and radiotherapy or temozolomide after radiotherapy in newly diagnosed patients with high-grade gliomas, David Schiff, Annick Desjardins, Timothy Cloughesy, Tom Mikkelsen, Michael Glantz, Marc C. Chamberlain, David A. Reardon, and Patrick Y. Wen

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PreImplantation factor (PIF) therapy provides comprehensive protection against radiation induced pathologies, Reut Shainer, Osnat Almogi-Hazan, Arye Berger, Liad Hinden, Martin Mueller, Chaya Brodie, Cedric Simillion, Michael Paidas, Eytan R. Barnea, and Reuven Or

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Combination of vatalanib and a 20-HETE synthesis inhibitor results in decreased tumor growth in an animal model of human glioma, Adarsh Shankar, Thaiz F. Borin, Asm Iskander, Nadimpalli R. Varma, Bhagelu R. Achyut, Meenu Jain, Tom Mikkelsen, Austin M. Guo, Wilson B. Chwang, James R. Ewing, Hassan Bagher-Ebadian, and Ali S. Arbab

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Intraoperative MRI for deep brain stimulation lead placement in Parkinson's disease: 1 year motor and neuropsychological outcomes, Christos Sidiropoulos, Richard Rammo, Bradley Merker, Abhimanyu Mahajan, Peter A. LeWitt, Patricia Kaminski, Melissa Womble, Adrianna Zec, Danette Taylor, Julia Wall, and Jason M. Schwalb

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TCGA Workflow: Analyze cancer genomics and epigenomics data using Bioconductor packages, Tiago C. Silva, Antonio Colaprico, Catharina Olsen, Fulvio D'Angelo, Gianluca Bontempi, Michele Ceccarelli, and Houtan Noushmehr

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New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs, Dominik Sturm, Brent A. Orr, Umut H. Toprak, Volker Hovestadt, David TW Jones, David Capper, Martin Sill, Ivo Buchhalter, Paul A. Northcott, Irina Leis, Marina Ryzhova, Christian Koelsche, Elke Pfaff, Sariah J. Allen, Gnanaprakash Balasubramanian, Barbara C. Worst, Kristian W. Pajtler, Sebastian Brabetz, Pascal D. Johann, Felix Sahm, Jüri Reimand, Alan Mackay, Diana M. Carvalho, Marc Remke, Joanna J. Phillips, Arie Perry, Cynthia Cowdrey, Rachid Drissi, Maryam Fouladi, Felice Giangaspero, Maria Lastowska, Wiesława Grajkowska, Wolfram Scheurlen, Torsten Pietsch, Christian Hagel, Johannes Gojo, Daniela Lötsch, Walter Berger, Irene Slavc, Christine Haberler, Anne Jouvet, Stefan Holm, Silvia Hofer, Marco Prinz, Catherine Keohane, Iris Fried, Christian Mawrin, David Scheie, Bret C Mobley, Matthew J Schniederjan, Mariarita Santi, Anna M Buccoliero, Sonika Dahiya, Christof M Kramm, André O von Bueren, Katja von Hoff, Stefan Rutkowski, Christel Herold-Mende, Michael C Frühwald, Till Milde, Martin Hasselblatt, Pieter Wesseling, Jochen Rößler, Ulrich Schüller, Martin Ebinger, Jens Schittenhelm, Stephan Frank, Rainer Grobholz, Istvan Vajtai, Volkmar Hans, Reinhard Schneppenheim, Karel Zitterbart, V Peter Collins, Eleonora Aronica, Pascale Varlet, Stephanie Puget, Christelle Dufour, Jacques Grill, Dominique Figarella-Branger, Marietta Wolter, Martin U Schuhmann, Tarek Shalaby, Michael Grotzer, Timothy van Meter, Camelia-Maria Monoranu, Jörg Felsberg, Guido Reifenberger, Matija Snuderl, Lynn Ann Forrester, Jan Koster, Rogier Versteeg, Richard Volckmann, Peter van Sluis, Stephan Wolf, Tom Mikkelsen, Amar Gajjar, Kenneth Aldape, Andrew S Moore, Michael D Taylor, Chris Jones, Nada Jabado, Matthias A Karajannis, Roland Eils, Matthias Schlesner, Peter Lichter, Andreas von Deimling, Stefan M Pfister, David W Ellison, Andrey Korshunov, and Marcel Kool

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Therapeutic hypothermia and ischemic stroke: A literature review, Rizwan A. Tahir and Aqueel H. Pabaney

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Impact of provider level, training and gender on the utilization of palliative care and hospice in neuro-oncology: a North-American survey, Tobias Walbert, Michael Glantz, Lonni Schultz, and Vinay K. Puduvalli

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End-of-life care in patients with primary malignant brain tumors: early is better, Tobias Walbert and Andrea Pace

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CXCR4 increases in-vivo glioma perivascular invasion, and reduces radiation induced apoptosis: A genetic knockdown study, Viveka N. Yadav, Daniel Zamler, Gregory J. Baker, Padma Kadiyala, Anat Erdreich-Epstein, Ana C. de Carvalho, Tom Mikkelsen, Maria G. Castro, and Pedro R. Lowenstein

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Application of morphometric analysis to patients with lung cancer metastasis to the spine: a clinical study, Hesham M. Zakaria, Azam Basheer, David Boyce-Fappiano, Erinma Elibe, Lonni Schultz, Ian Lee, Farzan Siddiqui, Brent Griffith, and Victor Chang

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Diabetes Mellitus Impairs Cognitive Function in Middle-Aged Rats and Neurological Recovery in Middle-Aged Rats After Stroke, Li Zhang, Michael Chopp, Yanlu Zhang, Ye Xiong, Chao Li, Neema S. Sadry, Imane A. Rhaleb, Mei Lu, and Zheng Gang Zhang

Submissions from 2015

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The role of surgery in the management of patients with diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline, Manish K. Aghi, Brian V. Nahed, Andrew E. Sloan, Timothy C. Ryken, Steven N. Kalkanis, and Jeffrey J. Olson

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Phase II trial of sunitinib as adjuvant therapy after stereotactic radiosurgery in patients with 1-3 newly diagnosed brain metastases, Manmeet S. Ahluwalia, Samuel T. Chao, Michael W. Parsons, John H. Suh, Ding Wang, Tom Mikkelsen, Cathy J. Brewer, Kathy N. Smolenski, Cathy Schilero, Matthew Rump, Paul Elson, Lilyana Angelov, Gene H. Barnett, Michael A. Vogelbaum, Robert J. Weil, and David M. Peereboom

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Brain Malignancy Steering Committee clinical trials planning workshop: report from the Targeted Therapies Working Group, Brian M. Alexander, Evanthia Galanis, W KA Yung, Karla V. Ballman, James M. Boyett, Timothy F. Cloughesy, John F. Degroot, Jason T. Huse, Bhupinder Mann, Warren Mason, Ingo K. Mellinghoff, Tom Mikkelsen, Paul S. Mischel, Brian P. O'Neill, Michael D. Prados, Jann N. Sarkaria, Abdul Tawab-Amiri, Lorenzo Trippa, Xiaobu Ye, Keith L. Ligon, Donald A. Berry, and Patrick Y. Wen

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Phase I study of iniparib concurrent with monthly or continuous temozolomide dosing schedules in patients with newly diagnosed malignant gliomas, Jaishri O. Blakeley, Stuart A. Grossman, Tom Mikkelsen, Myrna R. Rosenfeld, David Peereboom, L B. Nabors, Andrew S. Chi, Gary Emmons, Ignacio Garcia Ribas, Jeffrey G. Supko, Serena Desideri, and Xiaobu Ye

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MRI-Tracked Tumor Vascular Changes in the Hours after Single-Fraction Irradiation, Stephen L. Brown, Tavarekere N. Nagaraja, Madhava P. Aryal, Swayamprava Panda, Glauber Cabral, Kelly A. Keenan, Rasha Elmghirbi, Tom Mikkelsen, David Hearshen, Robert A. Knight, Ning Wen, Jae-Ho Kim, and James R. Ewing

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The role of neuropathology in the management of patients with diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline, Daniel P. Cahill, Andrew E. Sloan, Brian V. Nahed, Kenneth D. Aldape, David N. Louis, Timothy C. Ryken, Steven N. Kalkanis, and Jeffrey J. Olson

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Idiopathic spinal cord herniation: an imaging diagnosis with a significant delay, Britton J. Carter, Brent Griffith, Lonni R. Schultz, Muwaffak M. Abdulhak, Daniel Newman, and Rajan Jain

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The Michigan Spine Surgery Improvement Collaborative: a statewide Collaborative Quality Initiative, Victor Chang, Jason M. Schwalb, David R. Nerenz, Lisa Pietrantoni, Sharon Jones, Michelle Jankowski, Nancy Oja-Tebbe, Stephen Bartol, and Muwaffak M. Abdulhak

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Hybrid Biosynthetic Autograft Extender for Use in Posterior Lumbar Interbody Fusion: Safety and Clinical Effectiveness, Mokbel Chedid, Kelly M. Tundo, Jon E. Block, and Jeffrey M. Muir

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Peritumoral tissue compression is predictive of exudate flux in a rat model of cerebral tumor: an MRI study in an embedded tumor, James R. Ewing, Tavarekere N. Nagaraja, Madhava P. Aryal, Kelly A. Keenan, Rasha Elmghirbi, Hassan Bagher-Ebadian, Swayamprava Panda, Mei Lu, Tom Mikkelsen, Glauber Cabral, and Stephen L. Brown

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The role of imaging in the management of adults with diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline, Sarah J. Fouke, Tammie Benzinger, Daniel Gibson, Timothy C. Ryken, Steven N. Kalkanis, and Jeffrey J. Olson

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RTVP-1 promotes mesenchymal transformation of glioma via a STAT-3/IL-6-dependent positive feedback loop, Nis D. Giladi, Amotz Ziv-Av, Hae-Kyung Lee, Susan Finniss, Simona Cazacu, Cunli Xiang, Hiba Waldman Ben-Asher, Ana C. de Carvalho, Tom Mikkelsen, Laila M. Poisson, and Chaya Brodie

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Practice guideline: Idiopathic normal pressure hydrocephalus: Response to shunting and predictors of response: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology, John J. Halperin, Roger Kurlan, Jason M. Schwalb, Michael D. Cusimano, Gary Gronseth, and David Gloss

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In Reply: Stereotactic Microanatomy of the Nucleus Accumbens Stimulation for Obsessive-Compulsive Disorder: Reported Coordinates and Mavridis' Area, Clement Hamani, Julie Pilitsis, Anand I. Rughani, Joshua M. Rosenow, Parag G. Patil, Konstantin Slavin, Aviva Abosch, Emad Eskandar, Laura Mitchell, and Steven N. Kalkanis

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Association of early imaging for back pain with clinical outcomes in older adults, Jeffrey G. Jarvik, Laura S. Gold, Bryan A. Comstock, Patrick J. Heagerty, Sean D. Rundell, Judith A. Turner, Andrew L. Avins, Zoya Bauer, Brian W. Bresnahan, Janna L. Friedly, Kathryn James, Larry Kessler, Srdjan S. Nedeljkovic, David R. Nerenz, Xu Shi, Sean D. Sullivan, Leighton Chan, Jason M. Schwalb, and Richard A. Deyo

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Setting the stage: local delivery of cytoreductive agents for the treatment of glioblastoma, Steven N. Kalkanis

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Identification of regions of normal grey matter and white matter from pathologic glioblastoma and necrosis in frozen sections using Raman imaging, Rachel Kast, Gregory Auner, Sally Yurgelevic, Brandy Broadbent, Aditya Raghunathan, Laila M. Poisson, Tom Mikkelsen, Mark L. Rosenblum, and Steven N. Kalkanis

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Outcome of Adult Brain Tumor Consortium (ABTC) prospective dose-finding trials of I-125 balloon brachytherapy in high-grade gliomas: challenges in clinical trial design and technology development when MRI treatment effect and recurrence appear similar, L R. Kleinberg, V Stieber, Tom Mikkelsen, K Judy, J Weingart, G Barnett, J Olson, S Desideri, X Ye, and S Grossman

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A Multicenter, Phase II, Randomized, Noncomparative Clinical Trial of Radiation and Temozolomide with or without Vandetanib in Newly Diagnosed Glioblastoma Patients, Eudocia Q. Lee, Thomas J. Kaley, Dan G. Duda, David Schiff, Andrew B. Lassman, Eric T. Wong, Tom Mikkelsen, Benjamin W. Purow, Alona Muzikansky, Marek Ancukiewicz, Jason T. Huse, Shakti Ramkissoon, Jan Drappatz, Andrew D. Norden, Rameen Beroukhim, Stephanie E. Weiss, Brian M. Alexander, Christine S. McCluskey, Mary Gerard, Katrina H. Smith, Rakesh K. Jain, Tracy T. Batchelor, Keith L. Ligon, and Patrick Y. Wen

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Response assessment criteria for brain metastases: proposal from the RANO group, Nancy U. Lin, Eudocia Q. Lee, Hidefumi Aoyama, Igor J. Barani, Daniel P. Barboriak, Brigitta G. Baumert, Martin Bendszus, Paul D. Brown, D R. Camidge, Susan M. Chang, Janet Dancey, Elisabeth GE de Vries, Laurie E. Gaspar, Gordon J. Harris, F S. Hodi, Steven N. Kalkanis, Mark E. Linskey, David R. Macdonald, Kim Margolin, Minesh P. Mehta, David Schiff, Riccardo Soffietti, John H. Suh, Martin J. van den Bent, Michael A. Vogelbaum, and Patrick Y. Wen

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Bilateral medial medullary infarction presenting as Guillain Barré Syndrome: A diagnostic challenge, Mayra Montalvo, Rushna Ali, and Muhib Khan

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Two cilengitide regimens in combination with standard treatment for patients with newly diagnosed glioblastoma and unmethylated MGMT gene promoter: results of the open-label, controlled, randomized phase II CORE study, L B. Nabors, Karen L. Fink, Tom Mikkelsen, Danica Grujicic, Rafal Tarnawski, Do-Hyun Nam, Maria Mazurkiewicz, Michael Salacz, Lynn Ashby, Vittorina Zagonel, Roberta Depenni, James R. Perry, Christine Hicking, Martin Picard, Monika E. Hegi, Benoit Lhermitte, and David A. Reardon

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Direct regional microvascular monitoring and assessment of blood brain barrier function following cerebral ischemia-reperfusion injury, Tavarekere N. Nagaraja, Kelly A. Keenan, James R. Ewing, Sukruth Shashikumar, Varun Nadig, Raveena Munnangi, and Robert A. Knight

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Management of patients with recurrence of diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline, Brian V. Nahed, Navid Redjal, Daniel J. Brat, Andrew S. Chi, Kevin Oh, Tracy T. Batchelor, Timothy C. Ryken, Steven N. Kalkanis, and Jeffrey J. Olson

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Addition of MR imaging features and genetic biomarkers strengthens glioblastoma survival prediction in TCGA patients, Manal Nicolasjilwan, Ying Hu, Chunhua Yan, Daoud Meerzaman, Chad A. Holder, David Gutman, Rajan Jain, Rivka Colen, Daniel L. Rubin, Pascal O. Zinn, Scott N. Hwang, Prashant Raghavan, Dima A. Hammoud, Lisa Scarpace, Tom Mikkelsen, James Chen, Olivier Gevaert, Kenneth Buetow, John Freymann, Justin Kirby, Adam E. Flanders, and Max Wintermark

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Evidence-based clinical practice parameter guidelines for the treatment of adults with diffuse low grade glioma: introduction and methods, Jeffrey J. Olson, Steven N. Kalkanis, and Timothy C. Ryken

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Successful Management of Hemorrhage-Associated Hemiballism After Subthalamic Nucleus Deep Brain Stimulation with Pallidal Stimulation: a Case Report, Aqueel H. Pabaney, Rushna Ali, Peter A. LeWitt, Christos Sidiropoulos, and Jason M. Schwalb

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Endovascular management of fusiform aneurysm of anterior temporal artery: Technical report, Aqueel H. Pabaney, Paul A. Mazaris, Maximillian K. Kole, and Kevin A. Reinard

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Novel technique for cranial reconstruction following retrosigmoid craniectomy using demineralized bone matrix, Aqueel H. Pabaney, Kevin A. Reinard, Karam Asmaro, and Ghaus Malik

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High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma, Christine E. Quartararo, Eduard Reznik, Ana C. de Carvalho, Tom Mikkelsen, and Brent R. Stockwell

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The role of biopsy in the management of patients with presumed diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline, Brian T. Ragel, Timothy C. Ryken, Steven N. Kalkanis, Mateo Ziu, Daniel Cahill, and Jeffrey J. Olson

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Surgical Management of Giant Intracranial Arteriovenous Malformations: A Single Center Experience over 32 years, Kevin A. Reinard, Aqueel H. Pabaney, Azam Basheer, Scott B. Phillips, Maximillian K. Kole, and Ghaus Malik

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Simple and reproducible linear measurements to determine ventricular enlargement in adults, Kevin Reinard, Azam Basheer, Scott Phillips, Allison Snyder, Ajay Agarwal, Kourosh Jafari-Khouzani, Hamid Soltanian-Zadeh, Lonni Schultz, Todd Aho, and Jason M. Schwalb

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Further evidence for a pain pathway involving the cingulate gyrus: a case of chronic cluster headache cured by glioblastoma, Adam Robin, Aqueel H. Pabaney, Panayiotis Mitsias, and Jason M. Schwalb

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Low grade glioma guidelines: Foreword, Jack Rock

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The role of radiotherapy in the management of patients with diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline, Timothy C. Ryken, Ian Parney, John Buatti, Steven N. Kalkanis, and Jeffrey J. Olson

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Prenatal Diagnosis of Congenital Dermal Sinus, Sharif Sakr, Yedathore Mohan, Asif Malik, Ghaus Malik, and Bernard Gonik