Scholarly journal articles authored by members of the Division of Hematology/Oncology and the Henry Ford Cancer Institute at Henry Ford Health.

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Submissions from 2022

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Quality of life in a large multinational haemophilia B cohort (The B-Natural study) - Unmet needs remain, Erik Berntorp, Petra LeBeau, Margaret V. Ragni, Munira Borhany, Yasmina L. Abajas, Michael D. Tarantino, Katharina Holstein, Stacy E. Croteau, Raina Liesner, Cristina Tarango, Manuela Carvalho, Catherine McGuinn, Eva Funding, Christine L. Kempton, Christoph Bidlingmaier, Alice Cohen, Johannes Oldenburg, Susan Kearney, Christine Knoll, Philip Kuriakose, Suchitra Acharya, Ulrike M. Reiss, Roshni Kulkarni, Michelle Witkop, Stefan Lethagen, Rebecca Krouse, Amy D. Shapiro, and Jan Astermark

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Thinking Beyond Bacterial Infection: A Case of Cutaneous Blastomycosis, Mehakmeet Bhatia, Vivek Kak, Parth Patel, and Alexander A. Slota

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A Phase 1b Study of Telisotuzumab Vedotin in Combination With Nivolumab in Patients With NSCLC, D. Ross Camidge, Fabrice Barlesi, Jonathan W. Goldman, Daniel Morgensztern, Rebecca Heist, Everett Vokes, Eric Angevin, David S. Hong, Igor I. Rybkin, Minal Barve, Todd M. Bauer, Angelo Delmonte, Martin Dunbar, Monica Motwani, Apurvasena Parikh, Elysa Noon, Jun Wu, Vincent Blot, and Karen Kelly

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Abiraterone acetate for treatment of ectopic Cushing syndrome caused by ACTH-producing neuroendocrine tumor: a case report, Rebecca Chacko, Nayef H. Abdel-Razeq, Fawzi Abu Rous, and Randa Loutfi

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Dystrophic Nails: An Unusual Clue to Recurrent Lymphoma, Medha R. Cherabuddi and Vijayalakshmi Donthireddy

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Nasogastric Feeding Tube/Dobhoff Placement: A Multidisciplinary Approach to the Management of Malnutrition During Radiation Therapy in Patients With Head and Neck Cancer, Alexandra V. Coke, Marissa Gilbert, Sue Hill, and Farzan Siddiqui

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Olutasidenib (FT-2102) in patients with relapsed or refractory IDH1-mutant glioma: a multicenter, open-label, phase 1b/2 trial, Macarena I. de la Fuente, Howard Colman, Mark Rosenthal, Brian A. Van Tine, Danijela Levacic, Tobias Walbert, Hui K. Gan, Maria Vieito, Mohammed M. Milhem, Kathryn Lipford, Sanjeev Forsyth, Sylvie M. Guichard, Yelena Mikhailov, Alexander Sedkov, Julie Brevard, Patrick F. Kelly, Hesham Mohamed, and Varun Monga

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NVL-520 is a selective, TRK-sparing, and brain-penetrant inhibitor of ROS1 fusions and secondary resistance mutations., Alexander Drilon, Joshua C. Horan, Anupong Tangpeerachaikul, Benjamin Besse, Sai-Hong Ignatius Ou, Shirish M. Gadgeel, D. Ross Camidge, Anthonie J. van der Wekken, Linh Nguyen-Phuong, Adam Acker, Clare Keddy, Katelyn S. Nicholson, Satoshi Yoda, Scot Mente, Yuting Sun, John R. Soglia, Nancy E. Kohl, James R. Porter, Matthew D. Shair, Viola Zhu, Monika A. Davare, Aaron N. Hata, Henry E. Pelish, and Jessica J. Lin

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Circulating Cell-free DNA as a Prognostic Biomarker in Patients with Advanced ALK+ Non-small Cell Lung Cancer in the Global Phase III ALEX Trial, Rafal Dziadziuszko, Solange Peters, Tony Mok, D. Ross Camidge, Shirish M. Gadgeel, Sai-Hong Ignatius Ou, Krzysztof Konopa, Johannes Noé, Malgorzata Nowicka, Walter Bordogna, Peter N. Morcos, Vlatka Smoljanovic, and Alice T. Shaw

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Geriatric risk factors for serious COVID-19 outcomes among older adults with cancer: a cohort study from the COVID-19 and Cancer Consortium, Arielle Elkrief, Cassandra Hennessy, Nicole M. Kuderer, Samuel M. Rubinstein, Elizabeth Wulff-Burchfield, Rachel P. Rosovsky, Karen Vega-Luna, Michael A. Thompson, Orestis A. Panagiotou, Aakash Desai, Donna R. Rivera, Ali Raza Khaki, Lisa Tachiki, Ryan C. Lynch, Catherine Stratton, Rawad Elias, Gerald Batist, Anup Kasi, Dimpy P. Shah, Ziad Bakouny, Angelo Cabal, Jessica Clement, Jennifer Crowell, Becky Dixon, Christopher R. Friese, Stacy L. Fry, Punita Grover, Shuchi Gulati, Shilpa Gupta, Clara Hwang, Hina Khan, Soo Jung Kim, Elizabeth J. Klein, Chris Labaki, Rana R. McKay, Amanda Nizam, Nathan A. Pennell, Matthew Puc, Andrew L. Schmidt, Armin Shahrokni, Justin A. Shaya, Christopher T. Su, Sarah Wall, Nicole Williams, Trisha M. Wise-Draper, Sanjay Mishra, Petros Grivas, Benjamin French, Jeremy L. Warner, and Tanya M. Wildes

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Demographic differences among patients treated with chimeric antigen receptor T-cell therapy in the United States, Josephine Emole, Odunayo Lawal, Oleksandra Lupak, Ajoy Dias, Leyla Shune, and Korede Yusuf

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Chemotherapy as Treatment for Acute Myeloid Leukemia (AML)-Induced Facial Nerve Palsy, Michael Fana, Brook Centofanti, and Philip Kuriakose

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Association of Immune Checkpoint Inhibitors With Neurologic Adverse Events: A Systematic Review and Meta-analysis., Muhammad Zain Farooq, Sheeba Ba Aqeel, Prasanth Lingamaneni, Rayli Pichardo, Aleeza Jawed, Saad Khalid, Shristi Upadhyay Banskota, Pingfu Fu, and Ankit Mangla

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Benefit of adjuvant chemotherapy in node-negative T1a versus T1b and T1c triple-negative breast cancer, Genevieve A. Fasano, Solange Bayard, Yalei Chen, Leticia Varella, Tessa Cigler, Jessica Bensenhaver, Rache Simmons, Alexander Swistel, Jennifer Marti, Anne Moore, Eleni Andreopoulou, John Ng, Andrew Brandmaier, Silvia Formenti, Haythem Y. Ali, Melissa Davis, and Lisa Newman

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Racial Disparities in COVID-19 Outcomes Among Black and White Patients With Cancer, Julie Fu, Sonya A. Reid, Benjamin French, Cassandra Hennessy, Clara Hwang, Na Tosha Gatson, Narjust Duma, Sanjay Mishra, Ryan Nguyen, Jessica E. Hawley, Sunny R. K. Singh, David D. Chism, Neeta K. Venepalli, Jeremy L. Warner, Toni K. Choueiri, Andrew L. Schmidt, Leslie A. Fecher, Jennifer E. Girard, Mehmet A. Bilen, Deepak Ravindranathan, Sharad Goyal, Trisha M. Wise-Draper, Cathleen Park, Corrie A. Painter, Sheila M. McGlown, Gilberto de Lima Lopes, Oscar K. Serrano, and Dimpy P. Shah

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Pemetrexed and Platinum Plus Pembrolizumab in Patients With Metastatic Nonsquamous NSCLC by Tumor Burden at Baseline: A Post Hoc Efficacy Analysis of KEYNOTE-189, Shirish M. Gadgeel, Jhanelle E. Gray, Maria Teresa Rizzo, Patrick Peterson, Jong Seok Kim, and Delvys Rodríguez-Abreu

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Comparison of SP142 and 22C3 Immunohistochemistry PD-L1 Assays for Clinical Efficacy of Atezolizumab in Non-Small Cell Lung Cancer: Results From the Randomized OAK Trial, Shirish M. Gadgeel, Fred R. Hirsch, Keith Kerr, Fabrice Barlesi, Keunchil Park, Achim Rittmeyer, Wei Zou, Namrata Bhatia, Hartmut Koeppen, Sarah M. Paul, David Shames, Jing Yi, Christina Matheny, Marcus Ballinger, Mark McCleland, and David R. Gandara

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Response to "An approach to insulin tapering and discontinuation after glucagon-like peptide-1 receptor agonist initiation"., Jamie George, Nada Farhat, and Emily Thomas

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Rapid Reductions in Breast Density following Tamoxifen Therapy as Evaluated by Whole-Breast Ultrasound Tomography, Gretchen L. Gierach, Mark Sak, Shaoqi Fan, Ruth M. Pfeiffer, Maya Palakal, Cody Ramin, Lisa Bey-Knight, Michael S. Simon, David Gorski, Haythem Y. Ali, Peter Littrup, Mark E. Sherman, and Nebojsa Duric

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Comparative Clinical Outcomes Between EGFR Ex20ins and Wildtype NSCLC Treated with Immune Checkpoint Inhibitors, Nicolas Girard, Anna Minchom, Sai-Hong Ignatius Ou, Shirish M. Gadgeel, José Trigo, Santiago Viteri, Joshua M. Bauml, Anil Londhe, Parthiv Mahadevia, and Lyudmila Bazhenova

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Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells, Christopher J. Halbrook, Galloway Thurston, Seth Boyer, Cecily Anaraki, Jennifer A. Jiménez, Amy McCarthy, Nina G. Steele, Samuel A. Kerk, Hanna S. Hong, Lin Lin, Fiona V. Law, Catherine Felton, Lorenzo Scipioni, Peter Sajjakulnukit, Anthony Andren, Alica K. Beutel, Rima Singh, Barbara S. Nelson, Fran Van Den Bergh, Abigail S. Krall, Peter J. Mullen, Li Zhang, Sandeep Batra, Jennifer P. Morton, Ben Z. Stanger, Heather R. Christofk, Michelle A. Digman, Daniel A. Beard, Andrea Viale, Ji Zhang, Howard C. Crawford, Marina Pasca di Magliano, Claus Jorgensen, and Costas A. Lyssiotis

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Assessment of Regional Variability in COVID-19 Outcomes Among Patients With Cancer in the United States, Jessica E. Hawley, Tianyi Sun, David D. Chism, Narjust Duma, Julie C. Fu, Na Tosha N. Gatson, Sanjay Mishra, Ryan H. Nguyen, Sonya A. Reid, Oscar K. Serrano, Sunny R. K. Singh, Neeta K. Venepalli, Ziad Bakouny, Babar Bashir, Mehmet A. Bilen, Paolo F. Caimi, Toni K. Choueiri, Scott J. Dawsey, Leslie A. Fecher, Daniel B. Flora, Christopher R. Friese, Michael J. Glover, Cyndi J. Gonzalez, Sharad Goyal, Thorvardur R. Halfdanarson, Dawn L. Hershman, Hina Khan, Chris Labaki, Mark A. Lewis, Rana R. McKay, Ian Messing, Nathan A. Pennell, Matthew Puc, Deepak Ravindranathan, Terence D. Rhodes, Andrea V. Rivera, John Roller, Gary K. Schwartz, Sumit A. Shah, Justin A. Shaya, Mitrianna Streckfuss, Michael A. Thompson, Elizabeth M. Wulff-Burchfield, Zhuoer Xie, Peter Paul Yu, Jeremy L. Warner, Dimpy P. Shah, Benjamin French, and Clara Hwang

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Improved prediction of radiation pneumonitis by combining biological and radiobiological parameters using a data-driven Bayesian network analysis, Tonaye Hinton, David Karnak, Ming Tang, Ralph Jiang, Yi Luo, Philip Boonstra, Yilun Sun, Derek J. Nancarrow, Erin Sandford, Paramita Ray, Christopher Maurino, Martha Matuszak, Matthew J. Schipper, Michael D. Green, Gregory A. Yanik, Muneesh Tewari, Issam El Naqa, Caitlin A. Schonewolf, Randall Ten Haken, Shruti Jolly, Theodore S. Lawrence, and Dipankar Ray

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Myeloid- and Epithelial-Derived HBEGF Promotes Pulmonary Fibrosis, Elissa M. Hult, Stephen J. Gurczynski, David N. O'Dwyer, Rachel L. Zemans, Andrew Rasky, Yizhuo Wang, Susan Murray, Howard C. Crawford, and Bethany B. Moore

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Adagrasib in Non-Small-Cell Lung Cancer Harboring a KRAS(G12C) Mutation, Pasi A. Jänne, Gregory J. Riely, Shirish M. Gadgeel, Rebecca S. Heist, Sai-Hong I. Ou, Jose M. Pacheco, Melissa L. Johnson, Joshua K. Sabari, Konstantinos Leventakos, Edwin Yau, Lyudmila Bazhenova, Marcelo V. Negrao, Nathan A. Pennell, Jun Zhang, Kenna Anderes, Hirak Der-Torossian, Thian Kheoh, Karen Velastegui, Xiaohong Yan, James G. Christensen, Richard C. Chao, and Alexander I. Spira

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Benefits and Challenges of a Peer-Reviewed Approach to Meeting CoC Standard 6.1: Cancer Registry Quality Control, Rosann Keller and Afreen Siddiqui

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Cardiac Rehabilitation Improves Fitness in Patients With Subclinical Markers of Cardiotoxicity While Receiving Chemotherapy: A RANDOMIZED CONTROLLED STUDY, Dennis J. Kerrigan, Madhulata Reddy, Eleanor M. Walker, Bernard Cook, James McCord, Randa Loutfi, Matthew A. Saval, Jodi Baxter, Clinton A. Brawner, and Steven J. Keteyian

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Targeting Cellular Metabolism With CPI-613 Sensitizes Pancreatic Cancer Cells to Radiation Therapy, Husain Yar Khan, Mandana Kamgar, Amro Aboukameel, Sahar Bannoura, Brian Y. Chung, Yiwei Li, Mohammed Najeeb Al Hallak, Philip A. Philip, Susan Tsai, Sanjeev Luther, William A. Hall, and Asfar S. Azmi

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Brief Report: Safety and Antitumor Activity of Alectinib Plus Atezolizumab From a Phase 1b Study in Advanced ALK-Positive NSCLC, Dong-Wan Kim, Shirish M. Gadgeel, Scott N. Gettinger, Gregory J. Riely, Geoffrey R. Oxnard, Tarek Mekhail, Peter Schmid, Afshin Dowlati, Rebecca S. Heist, Antoinette J. Wozniak, Jatinder Singh, Edward Cha, Jessica Spahn, and Sai-Hong Ignatius Ou

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American Radium Society (ARS) Appropriate Use Criteria (AUC) for Locoregional Gastric Adenocarcinoma: Systematic Review and Guidelines, Rachit Kumar, Leila Tchelebi, Christopher J. Anker, Navesh Sharma, Nancy A. Bianchi, Jadranka Dragovic, Karyn A. Goodman, Joseph M. Herman, Yixing Jiang, William E. Jones, Timothy J. Kennedy, Percy Lee, Madappa Kundranda, Suzanne Russo, William Small, Wonsuk W. Suh, Nelson Yee, and Salma K. Jabbour

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Cetuximab and anemia prevention in head and neck cancer patients undergoing radiotherapy, Lucas G. Maahs, Ahmed I. Ghanem, Radhika Gutta, Amy Tang, Swarn Arya, Zaid Al-Saheli, Haythem Y. Ali, Steven S. Chang, Samantha Tam, Vivian Wu, Farzan Siddiqui, and Jawad Z. Sheqwara

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African Ancestry Associated Gene Expression Profiles in Triple Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent, Rachel Martini, Princesca Delpe, Timothy R. Chu, Kanika Arora, Brittany Lord, Akanksha Verma, Deepa Bedi, Balasubramanyam Karanam, Isra Elhussin, Yalei Chen, Endale Gebregzabher, Joseph K. Oppong, Ernest K. Adjei, Aisha Jibril Suleiman, Baffour Awuah, Mahteme Bekele Muleta, Engida Abebe, Ishmael Kyei, Frances S. Aitpillah, Michael O. Adinku, Kwasi Ankomah, Ernest Baawuah Osei-Bonsu, Dhananjay A. Chitale, Jessica M. Bensenhaver, Saul David Nathanson, LaToya Jackson, Lindsay F. Petersen, Erica Proctor, Brian Stonaker, Kofi K. Gyan, Lee D. Gibbs, Zarko Manojlovic, Rick A. Kittles, Jason White, Clayton C. Yates, Upender Manne, Kevin Gardner, Nigel Mongan, Esther Cheng, Paula Ginter, Syed Hoda, Olivier Elemento, Nicolas Robine, Andrea Sboner, John D. Carpten, Lisa Newman, and Melissa B. Davis

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Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer, Ashley M. Mello, Tenzin Ngodup, Yusoo Lee, Katelyn L. Donahue, Jinju Li, Arvind Rao, Eileen S. Carpenter, Howard C. Crawford, Marina Pasca di Magliano, and Kyoung Eun Lee

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Amivantamab compared with real-world therapies in patients with advanced non-small cell lung cancer harboring EGFR exon 20 insertion mutations who progressed after platinum-based chemotherapy, Anna Minchom, Santiago Viteri, Lyudmila Bazhenova, Shirish M. Gadgeel, Sai-Hong Ignatius Ou, José Trigo, Joshua M. Bauml, Daniel Backenroth, Archan Bhattacharya, Tracy Li, Parthiv Mahadevia, and Nicolas Girard

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A novel prognostic model predicting overall survival in patients with metastatic castration-resistant prostate cancer receiving standard chemotherapy: A multi-trial cohort analysis, Daniele Modonutti, Sami E. Majdalani, Nicholas Corsi, Pin Li, Akshay Sood, Deepansh Dalela, Marcus L. Jamil, Clara Hwang, Mani Menon, Craig G. Rogers, Quoc-Dien Trinh, Giacomo Novara, and Firas Abdollah

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Concordance Between Tissue ALK Detection by Immunohistochemistry and Plasma ALK Detection by Next-Generation Sequencing in the Randomized Phase 3 ALEX Study in Patients With Treatment-Naive Advanced ALK-Positive NSCLC, Johannes Noé, Walter Bordogna, Venice Archer, Vlatka Smoljanovic, Magalie Hilton, Ryan Woodhouse, Simonetta Mocci, and Shirish M. Gadgeel

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First-in-Human Phase I/IB Dose-Finding Study of Adagrasib (MRTX849) in Patients With Advanced KRAS(G12C) Solid Tumors (KRYSTAL-1), Sai-Hong Ignatius Ou, Pasi A. Jänne, Ticiana A. Leal, Igor I. Rybkin, Joshua K. Sabari, Minal A. Barve, Lyudmila A. Bazhenova, Melissa L. Johnson, Karen L. Velastegui, Cornelius Cilliers, James G. Christensen, Xiaohong Yan, Richard C. Chao, and Kyriakos P. Papadopoulos

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Continuation of Lorlatinib in ALK-Positive NSCLC Beyond Progressive Disease, Sai-Hong I. Ou, Benjamin J. Solomon, Alice T. Shaw, Shirish M. Gadgeel, Benjamin Besse, Ross A. Soo, Antonello Abbattista, Francesca Toffalorio, Robin Wiltshire, and Alessandra Bearz

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Phase I Study of Glesatinib (MGCD265) in Combination with Erlotinib or Docetaxel in Patients with Advanced Solid Tumors, Amita Patnaik, Shirish M. Gadgeel, Kyriakos P. Papadopoulos, Drew W. Rasco, Naomi B. Haas, Hirak Der-Torossian, Demiana Faltaos, Diane Potvin, Vanessa Tassell, Manal Tawashi, Richard Chao, and Peter J. O'Dwyer

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Atezolizumab versus chemotherapy in advanced or metastatic NSCLC with high blood-based tumor mutational burden: primary analysis of BFAST cohort C randomized phase 3 trial, Solange Peters, Rafal Dziadziuszko, Alessandro Morabito, Enriqueta Felip, Shirish M. Gadgeel, Parneet Cheema, Manuel Cobo, Zoran Andric, Carlos H. Barrios, Masafumi Yamaguchi, Eric Dansin, Pongwut Danchaivijitr, Melissa Johnson, Silvia Novello, Michael S. Mathisen, Sarah M. Shagan, Erica Schleifman, Jin Wang, Mark Yan, Simonetta Mocci, David Voong, David A. Fabrizio, David S. Shames, Todd Riehl, David R. Gandara, and Tony Mok

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Comparison Between the 2021 USPSTF Lung Cancer Screening Criteria and Other Lung Cancer Screening Criteria for Racial Disparity in Eligibility, Chan Yeu Pu, Christine M. Lusk, Christine Neslund-Dudas, Shirish M. Gadgeel, Ayman O. Soubani, and Ann G. Schwartz

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Lung Cancer Screening Criteria and Cardiopulmonary Comorbidities, Chan Yeu Pu, Christine M. Lusk, Christine Neslund-Dudas, Shirish M. Gadgeel, Ayman O. Soubani, and Ann G. Schwartz

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Thrombotic Thrombocytopenic Purpura After Ad6.COV2.S Vaccination, Sruthi Ramanan, Harjinder Singh, Priya Menon, Parth M. Patel, Vrajesh Parmar, and Devin Malik

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Patients recently treated for B-lymphoid malignancies show increased risk of severe COVID-19: a CCC19 registry analysis, Samuel M. Rubinstein, Divaya Bhutani, Ryan C. Lynch, Chih-Yuan Hsu, Yu Shyr, Shailesh Advani, Ruben A. Mesa, Sanjay Mishra, Daniel P. Mundt, Dimpy P. Shah, R. Alejandro Sica, Keith E. Stockerl-Goldstein, Catherine Stratton, Matthias Weiss, Alicia Beeghly-Fadiel, Melissa Accordino, Sarit E. Assouline, Joy Awosika, Ziad Bakouny, Babar Bashir, Stephanie Berg, Mehmet Asim Bilen, Cecilia A. Castellano, Jacob C. Cogan, Devendra Kc, Christopher R. Friese, Shilpa Gupta, Daniel Hausrath, Clara Hwang, Nathalie A. Johnson, Monika Joshi, Anup Kasi, Elizabeth J. Klein, Vadim S. Koshkin, Nicole M. Kuderer, Daniel H. Kwon, Chris Labaki, Tahir Latif, Eric Lau, Xuanyi Li, Gary H. Lyman, Rana R. McKay, Gayathri Nagaraj, Amanda Nizam, Taylor K. Nonato, Adam J. Olszewski, Hyma V. Polimera, Andrew J. Portuguese, Matthew M. Puc, Pedram Razavi, Rachel Rosovski, Andrew Schmidt, Sumit A. Shah, Aditi Shastri, Christopher Su, Pallawi Torka, Trisha M. Wise-Draper, Leyre Zubiri, Jeremy L. Warner, and Michael A. Thompson

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Beyond Checkpoint Inhibitors: Enhancing Antitumor Immune Response in Lung Cancer, Rachel E. Sanborn, Famke L. Schneiders, Suresh Senan, and Shirish M. Gadgeel

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Coinfections in Patients With Cancer and COVID-19: A COVID-19 and Cancer Consortium (CCC19) Study, Gowri Satyanarayana, Kyle T. Enriquez, Tianyi Sun, Elizabeth J. Klein, Maheen Abidi, Shailesh M. Advani, Joy Awosika, Ziad Bakouny, Babar Bashir, Stephanie Berg, Marilia Bernardes, Pamela C. Egan, Arielle Elkrief, Lawrence E. Feldman, Christopher R. Friese, Shipra Goel, Cyndi Gonzalez Gomez, Keith L. Grant, Elizabeth A. Griffiths, Shuchi Gulati, Shilpa Gupta, Clara Hwang, Jayanshu Jain, Chinmay Jani, Anna Kaltsas, Anup Kasi, Hina Khan, Natalie Knox, Vadim S. Koshkin, Daniel H. Kwon, Chris Labaki, Gary H. Lyman, Rana R. McKay, Christopher McNair, Gayathri Nagaraj, Elizabeth S. Nakasone, Ryan Nguyen, Taylor K. Nonato, Adam J. Olszewski, Orestis A. Panagiotou, Matthew Puc, Pedram Razavi, Elizabeth V. Robilotti, Miriam Santos-Dutra, Andrew L. Schmidt, Dimpy P. Shah, Sumit A. Shah, Kendra Vieira, Lisa B. Weissmann, Trisha M. Wise-Draper, Ulysses Wu, Julie Tsu-Yu Wu, Toni K. Choueiri, Sanjay Mishra, Jeremy L. Warner, Benjamin French, and Dimitrios Farmakiotis

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COVID-19 vaccination and breakthrough infections in patients with cancer, A L Schmidt, C Labaki, C-Y Hsu, Z Bakouny, Nino Balanchivadze, S A Berg, S Blau, A Daher, T El Zarif, C R Friese, E A Griffiths, J E Hawley, B Hayes-Lattin, V Karivedu, T Latif, B H Mavromatis, R R McKay, G Nagaraj, R H Nguyen, O A Panagiotou, A J Portuguese, M Puc, M Santos Dutra, B A Schroeder, A Thakkar, E M Wulff-Burchfield, S Mishra, D Farmakiotis, Yu Shyr, J L Warner, and T K Choueiri

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Personal Systemic Therapy Decision-Making has Officially Arrived for Node-Positive Breast Cancer, Theresa Schwartz

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ASO Visual Abstract: Surgical Management of the Axilla in Breast Cancer-Evolving but Still Necessary, Theresa Schwartz, Ashley D. Marumoto, and Armando E. Giuliano

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Presentation of Sjogren Syndrome as Nodular Pulmonary Amyloidosis, Harjinder Singh, Parth Patel, Sruthi Ramanan, Hazem Zebda, and Devin Malik

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EP08.02-018 Phase 1/2 Study of BLU-451, a Small Molecule Inhibitor of EGFR, in EGFR Exon 20 Insertion-Mutant Incurable Advanced Cancers, A. Spira, D. R. Spigel, R. Camidge, A. J. de Langen, T. M. Kim, K. Goto, Y. Elamin, E. Shum, K. L. Reckamp, J. Rotow, S. Goldberg, Shirish M. Gadgeel, T. A. Leal, F. Albayya, S. Fitzpatrick, M. Louie-Gao, J. Parepally, A. Zalutskaya, and H. Yu

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Inhibition of Tumor Microenvironment Cytokine Signaling Sensitizes Ovarian Cancer Cells to Antiestrogen Therapy, Lijun Tan, Katelyn Tondo-Steele, Caroline Foster, Carrie McIlwain, Danielle E. Bolland, Howard C. Crawford, Andrew Sciallis, and Karen McLean

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Adjuvant nab-Paclitaxel + Gemcitabine in Resected Pancreatic Ductal Adenocarcinoma: Results From a Randomized, Open-Label, Phase III Trial, Margaret A. Tempero, Uwe Pelzer, Eileen M. O'Reilly, Jordan Winter, Do-Youn Oh, Chung-Pin Li, Giampaolo Tortora, Heung-Moon Chang, Charles D. Lopez, Tanios Bekaii-Saab, Andrew H. Ko, Armando Santoro, Joon Oh Park, Marcus S. Noel, Giovanni Luca Frassineti, Yan-Shen Shan, Andrew Dean, Hanno Riess, Eric Van Cutsem, Jordan Berlin, Philip A. Philip, Malcolm Moore, David Goldstein, Josep Tabernero, Mingyu Li, Stefano Ferrara, Yvan Le Bruchec, George Zhang, Brian Lu, Andrew V. Biankin, and Michele Reni

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Aberrant transcription factors in the cancers of the pancreas, Md Hafiz Uddin, Md Najeeb Al-Hallak, Philip A. Philip, Herbert Chen, Bassel El-Rayes, and Asfar S. Azmi

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Role of Non-Coding RNAs in Pancreatic Ductal Adenocarcinoma Associated Cachexia, Md Hafiz Uddin, Ramzi M. Mohammad, Philip A. Philip, Asfar S. Azmi, and Irfana Muqbil

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Extrinsic KRAS Signaling Shapes the Pancreatic Microenvironment Through Fibroblast Reprogramming, Ashley Velez-Delgado, Katelyn L. Donahue, Kristee L. Brown, Wenting Du, Valerie Irizarry-Negron, Rosa E. Menjivar, Emily L. Lasse Opsahl, Nina G. Steele, Stephanie The, Jenny Lazarus, Veerin R. Sirihorachai, Wei Yan, Samantha B. Kemp, Samuel A. Kerk, Murali Bollampally, Sion Yang, Michael K. Scales, Faith R. Avritt, Fatima Lima, Costas A. Lyssiotis, Arvind Rao, Howard C. Crawford, Filip Bednar, Timothy L. Frankel, Benjamin L. Allen, Yaqing Zhang, and Marina Pasca di Magliano

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The Need for Rapid Cytogenetics in the Era of Unique Therapies for Acute Myeloid Leukemia, Anjanaa Vijayanarayanan, Brandon M. Shaw, Kathryn Gibbons, Kedar V. Inamdar, Philip Kuriakose, and Madhu P. Menon

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Clinical outcomes of preimplantation genetic testing for hereditary cancer syndromes: A systematic review, Natalie Vriesen, Erin P. Carmany, and Jaime L. Natoli

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Demographics, Outcomes, and Risk Factors for Patients with Sarcoma and COVID-19: A CCC19-Registry Based Retrospective Cohort Study, Michael J. Wagner, Cassandra Hennessy, Alicia Beeghly, Benjamin French, Dimpy P. Shah, Sarah Croessmann, Diana Vilar-Compte, Erika Ruiz-Garcia, Matthew Ingham, Gary K. Schwartz, Corrie A. Painter, Rashmi Chugh, Leslie Fecher, Cathleen Park, Olga Zamulko, Jonathan C. Trent, Vivek Subbiah, Ali Raza Khaki, Lisa Tachiki, Elizabeth S. Nakasone, Elizabeth T. Loggers, Chris Labaki, Renee Maria Saliby, Rana R. McKay, Archana Ajmera, Elizabeth A. Griffiths, Igor Puzanov, William D. Tap, Clara Hwang, Sheela Tejwani, Sachin R. Jhawar, Brandon Hayes-Lattin, Elizabeth Wulff-Burchfield, Anup Kasi, Daniel Y. Reuben, Gayathri Nagaraj, Monika Joshi, Hyma Polimera, Amit A. Kulkarni, Khashayar Esfahani, Daniel H. Kwon, Luca Paoluzzi, Mehmet A. Bilen, Eric B. Durbin, Petros Grivas, Jeremy L. Warner, and Elizabeth J. Davis

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Ptf1a Promoter-Driven Cre Expression During Spermatogenesis Causes Germline Recombination, Jiale Wang, Oliver Wang, Yan Bi, Ying Wang, Howard C. Crawford, and Baoan Ji

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KDM6A Loss Recruits Tumor-Associated Neutrophils and Promotes Neutrophil Extracellular Trap Formation in Pancreatic Cancer, Jing Yang, Lin Jin, Hong Sun Kim, Feng Tian, Zhujun Yi, Karan Bedi, Mats Ljungman, Marina Pasca di Magliano, Howard C. Crawford, and Jiaqi Shi

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Effect of Pevonedistat, an Investigational NEDD8-Activating Enzyme Inhibitor, on the QTc Interval in Patients With Advanced Solid Tumors, Xiaofei Zhou, Debra L. Richardson, Afshin Dowlati, Sanjay Goel, Solmaz Sahebjam, James Strauss, Sant Chawla, Ding Wang, Diane R. Mould, Vivek Samnotra, Douglas V. Faller, Karthik Venkatakrishnan, and Neeraj Gupta

Submissions from 2021

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Outcomes of patients with thrombocytopenia evaluated at hematology subspecialty clinics, Zaid H. Abdel Rahman, Kevin C. Miller, H Jabbour, Yaser Alkhatib, and Vijayalakshmi Donthireddy

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Renal infarction and papular-purpuric gloves and socks syndrome (PPGSS): rare extra-haematological manifestations of acute parvovirus B-19 infection, Fawzi Abu Rous, Qunfang Li, and Yue Guo

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Clinical significance of quantitative categorization of HER2 fluorescent in situ hybridization results in invasive breast cancer patients treated with HER2-targeted agents, Mohamed Alhamar, Bassam Alkamachi, Harshita Mehrotra, Jessica Sanchez, Haythem Y. Ali, Daniel Schultz, and Dhananjay A. Chitale

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p16 positive oropharyngeal small cell cancer: A case report, Nada Al Masalmeh, Geetika Kukreja, Feras Zaiem, S. Naweed Raza, Harold Kim, Misako Nagasaka, and Ammar Sukari

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A Dose-finding Study Followed by a Phase II Randomized, Placebo-controlled Trial of Chemoradiotherapy With or Without Veliparib in Stage III Non-small-cell Lung Cancer: SWOG 1206 (8811), Athanassios Argiris, Jieling Miao, Mihaela C. Cristea, Allen M. Chen, Jacob M. Sands, Roy H. Decker, Scott N. Gettinger, Megan E. Daly, Bryan A. Faller, Kathy S. Albain, Ronald H. Yanagihara, Linda L. Garland, Lauren A. Byers, Ding Wang, Marianna Koczywas, Mary W. Redman, Karen Kelly, and David R. Gandara

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P-selectin expression assay in a repeatedly serotonin-release assay-negative patient with heparin-induced thrombocytopenia, Kanika Arora, Shannon Rodgers, Yaser Alkhatib, Ifeoma Onwubiko, Anand Padmanabhan, and Zaher K. Otrock

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Acquired Resistance to KRAS (G12C) Inhibition in Cancer, Mark M. Awad, Shengwu Liu, Igor I. Rybkin, Kathryn C. Arbour, Julien Dilly, Viola W. Zhu, Melissa L. Johnson, Rebecca S. Heist, Tejas Patil, Gregory J. Riely, Joseph O. Jacobson, Xiaoping Yang, Nicole S. Persky, David E. Root, Kristen E. Lowder, Hanrong Feng, Shannon S. Zhang, Kevin M. Haigis, Yin P. Hung, Lynette M. Sholl, Brian M. Wolpin, Julie Wiese, Jason Christiansen, Jessica Lee, Alexa B. Schrock, Lee P. Lim, Kavita Garg, Mark Li, Lars D. Engstrom, Laura Waters, J. David Lawson, Peter Olson, Piro Lito, Sai-Hong I. Ou, James G. Christensen, Pasi A. Jänne, and Andrew J. Aguirre

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A Case of Chronic Eosinophilic Leukemia in a Patient With Recurrent Cough, Dyspnea, and Eosinophilia, Nino Balanchivadze, James P. Purtell, Jessica Anderson, Yue Guo, and Irina Dobrosotskaya

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NRG-HN003: Phase I and Expansion Cohort Study of Adjuvant Pembrolizumab, Cisplatin and Radiation Therapy in Pathologically High-Risk Head and Neck Cancer, Julie E. Bauman, Jonathan Harris, Ravindra Uppaluri, Min Yao, Robert L. Ferris, Josephine Chen, Richard C. Jordan, Nikhil P. Joshi, Srinivas Jujjuvaparu, Dukagjin M. Blakaj, Christina Henson, Jawad Sheqwara, Loren K. Mell, Neilayan Sen, David A. Clump, Madhur K. Garg, Emrullah Yilmaz, Pedro Torres-Saavedra, and Quynh-Thu Le

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Screening mammography mitigates breast cancer disparities through early detection of triple negative breast cancer, Solange Bayard, Genevieve Fasano, Yalei Chen, Melissa Davis, Michele Drotman, Jessica Bensenhaver, Alexander Swistel, Rache Simmons, Jennifer Marti, and Lisa Newman

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Comparative clinical outcomes for patients with advanced NSCLC harboring EGFR exon 20 insertion mutations and common EGFR mutations, Lyudmila Bazhenova, Anna Minchom, Santiago Viteri, Joshua M. Bauml, Sai-Hong Ignatius Ou, Shirish M. Gadgeel, José Manuel Trigo, Daniel Backenroth, Tracy Li, Anil Londhe, Parthiv Mahadevia, and Nicolas Girard

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Discovery of the pancreatic basal cell: a new candidate for an adult stem cell emerges, Simone Benitz and Howard C. Crawford

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Anticipating resistance to KRAS inhibition: a novel role for USP21 in macropinocytosis regulation, Howard C. Crawford

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Loss of the ciliary protein Chibby1 in mice leads to exocrine pancreatic degeneration and pancreatitis, Benjamin Cyge, Vera Voronina, Mohammed Hoque, Eunice N. Kim, Jason Hall, Jennifer M. Bailey-Lundberg, Gregory J. Pazour, Howard C. Crawford, Randall T. Moon, Feng-Qian Li, and Ken-Ichi Takemaru

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Portobelamides A and B and Caciqueamide, Cytotoxic Peptidic Natural Products from a Caldora sp. Marine Cyanobacterium, Ozlem Demirkiran, Jehad Almaliti, Tiago Leão, Gabriel Navarro, Tara Byrum, Frederick A. Valeriote, Lena Gerwick, and William H. Gerwick

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Executive Summary of the American Radium Society Appropriate Use Criteria for Radiation Treatment of Node-Negative Muscle Invasive Bladder Cancer, Tru-Khang T. Dinh, Timur Mitin, Hilary P. Bagshaw, Karen E. Hoffman, Clara Hwang, R. Jeffrey Karnes, Amar U. Kishan, Stanley L. Liauw, Shane Lloyd, Louis Potters, Timothy N. Showalter, Al V. Taira, Neha Vapiwala, Nicholas G. Zaorsky, Anthony V. D'Amico, Paul L. Nguyen, and Brian J. Davis

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Blood First Assay Screening Trial (BFAST) in Treatment-Naive Advanced or Metastatic NSCLC: Initial Results of the Phase 2 ALK-Positive Cohort, Rafal Dziadziuszko, Tony Mok, Solange Peters, Ji-Youn Han, Jorge Alatorre-Alexander, Natasha Leighl, Virote Sriuranpong, Maurice Pérol, Gilberto de Castro Junior, Ernest Nadal, Filippo de Marinis, Osvaldo Arén Frontera, Daniel S W Tan, Dae Ho Lee, Hye Ryun Kim, Mark Yan, Todd Riehl, Erica Schleifman, Sarah M. Paul, Simonetta Mocci, Rajesh Patel, Zoe June Assaf, David S. Shames, Michael S. Mathisen, and Shirish M. Gadgeel

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Long-Term Report of a Comprehensive Molecular and Genomic Analysis in NRG Oncology/RTOG 0424: A Phase II Study of Radiation and Temozolomide in High-Risk Grade II Glioma, Jessica L. Fleming, Stephanie L. Pugh, Barbara J. Fisher, Glenn J. Lesser, David R. Macdonald, Erica H. Bell, Joseph P. McElroy, Aline P. Becker, Cynthia D. Timmers, Kenneth D. Aldape, C. Leland Rogers, Thomas J. Doyle, Maria Werner-Wasik, Jean-Paul Bahary, Hsiang-Hsuan Michael Yu, David P. D'Souza, Nadia N. Laack, Penny K. Sneed, Young Kwok, Minhee Won, Minesh P. Mehta, and Arnab Chakravarti

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Patient-Reported Outcomes in the Era of Immunotherapy Trials, Shirish M. Gadgeel

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Fast progression in non-small cell lung cancer: results from the randomized phase III OAK study evaluating second-line atezolizumab versus docetaxel, David Gandara, Martin Reck, Denis Moro-Sibilot, Julien Mazieres, Shirish M. Gadgeel, Stefanie Morris, Andres Cardona, Diana Mendus, Marcus Ballinger, Achim Rittmeyer, and Solange Peters

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Safety of pemetrexed plus platinum in combination with pembrolizumab for metastatic nonsquamous non-small cell lung cancer: A post hoc analysis of KEYNOTE-189, Edward B. Garon, Joachim Aerts, Jong Seok Kim, Catherine E Muehlenbein, Patrick Peterson, Maria Teresa Rizzo, and Shirish M. Gadgeel

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The actual and ideal roles of haemophilia treatment centre social workers in the United States and the barriers to ideal roles, Margaret K. Geary, Ellen Kachalsky, and Aric Parnes

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Pembrolizumab plus dinaciclib in patients with hematologic malignancies: the phase 1b KEYNOTE-155 study, Gareth Peter Gregory, Shaji K. Kumar, Ding Wang, Daruka Mahadevan, Patricia A. Walker, Nina D. Wagner-Johnston, Carolina Escobar, Rajat Bannerji, Divava Bhutani, Julie E. Chang, Francisco J. Hernandez-Ilizaliturri, Andreas Klein, John M. Pagel, Witold Rybka, Andrew J. Yee, Anne Mohrbacher, Mo Huang, Mohammed Z. H. Farooqui, Patricia Marinello, and Hang Quach

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Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: a report from the COVID-19 and Cancer Consortium, P Grivas, A R Khaki, T M Wise-Draper, B French, C Hennessy, C-Y Hsu, Y Shyr, X Li, T K Choueiri, C A Painter, S Peters, B I Rini, M A Thompson, S Mishra, D R Rivera, J D Acoba, M Z Abidi, Z Bakouny, B Bashir, T Bekaii-Saab, S Berg, E H Bernicker, M A Bilen, P Bindal, R Bishnoi, N Bouganim, D W Bowles, A Cabal, P F Caimi, D D Chism, J Crowell, C Curran, A Desai, B Dixon, D B Doroshow, E B Durbin, A Elkrief, D Farmakiotis, A Fazio, L A Fecher, D B Flora, C R Friese, J Fu, Shirish M. Gadgeel, M D Galsky, D M Gill, M J Glover, S Goyal, P Grover, S Gulati, S Gupta, S Halabi, T R Halfdanarson, B Halmos, D J Hausrath, J E Hawley, E Hsu, M Huynh-Le, Clara Hwang, C Jani, A Jayaraj, D B Johnson, A Kasi, H Khan, V S Koshkin, N M Kuderer, D H Kwon, P E Lammers, A Li, A Loaiza-Bonilla, C A Low, M B Lustberg, G H Lyman, R R McKay, C McNair, H Menon, R A Mesa, V Mico, D Mundt, G Nagaraj, E S Nakasone, J Nakayama, A Nizam, N L Nock, C Park, J M Patel, K G Patel, P Peddi, N A Pennell, A J Piper-Vallillo, M Puc, D Ravindranathan, M E Reeves, D Y Reuben, L Rosenstein, R P Rosovsky, S M Rubinstein, M Salazar, A L Schmidt, G K Schwartz, M R Shah, S A Shah, C Shah, J A Shaya, Sunny R.K. Singh, M Smits, K E Stockerl-Goldstein, D G Stover, M Streckfuss, S Subbiah, L Tachiki, E Tadesse, A Thakkar, M D Tucker, A K Verma, D C Vinh, M Weiss, J T Wu, E Wulff-Burchfield, Z Xie, P P Yu, T Zhang, A Y Zhou, H Zhu, L Zubiri, D P Shah, J L Warner, and GdL Lopes

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Clinical outcomes of COVID-19 in patients with sickle cell disease and sickle cell trait: A critical appraisal of the literature, Wouter S. Hoogenboom, Tharun T. Alamuri, Daniel M. McMahon, Nino Balanchivadze, Vrushali Dabak, William B. Mitchell, Kerry B. Morrone, Deepa Manwani, and Tim Q. Duong

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Effect of ceritinib on the pharmacokinetics of coadministered CYP3A and 2C9 substrates: a phase I, multicenter, drug-drug interaction study in patients with ALK + advanced tumors, Felipe K. Hurtado, Filippo de Braud, Javier De Castro Carpeño, Maria Jose de Miguel Luken, Ding Wang, Jeffrey Scott, Yvonne Y. Lau, Tracey McCulloch, and Morten Mau-Sorensen

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Rapid real-world data analysis of patients with cancer, with and without COVID-19, across distinct health systems, Clara Hwang, Monika A. Izano, Michael A. Thompson, Shirish M. Gadgeel, James L. Weese, Tom Mikkelsen, Andrew Schrag, Mahder Teka, Sheetal Walters, Frank M. Wolf, Jonathan Hirsch, Donna R. Rivera, Paul G. Kluetz, Harpreet Singh, and Thomas D. Brown

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Multiethnic PDX models predict a possible immune signature associated with TNBC of African ancestry, Evelyn M. Jiagge, Peter J. Ulintz, Shukmei Wong, Sean P. McDermott, Sabrina I. Fossi, Tahra K. Suhan, Mark J. Hoenerhoff, Jessica M. Bensenhaver, Barbara Salem, Michele Dziubinski, Joseph K. Oppong, Francis Aitpillah, Kyei Ishmael, Ernest Osei-Bonsu, Ernest Adjei, Awuah Baffour, Jessica Aldrich, Ahmet Kurdoglu, Kurt Fernando, David W. Craig, Jeff M. Trent, Jun Li, Dhananjay A. Chitale, Lisa A. Newman, John D. Carpten, Max S. Wicha, and Sofia D. Merajver

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The long shadow of socioeconomic deprivation over the modern management of acute myeloid leukemia: time to unravel the challenges, M. Joseph John, Philip Kuriakose, Mark Smith, Eve Roman, and Sudhir Tauro

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Apolipoprotein E promotes immune suppression in pancreatic cancer through NF-kB-mediated production of CXCL1, Samantha B. Kemp, Eileen S. Carpenter, Nina G. Steele, Katelyn L. Donahue, Zeribe Chike Nwosu, Amanda Pacheco, Ashley Velez-Delgado, Rosa E. Menjivar, Fatima Lima, Stephanie The, Carlos E. Espinoza, Kristee Brown, Daniel Long, Costas A. Lyssiotis, Arvind Rao, Yaqing Zhang, Marina Pasca di Magliano, and Howard C. Crawford

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Myeloid Cell Mediated Immune Suppression in Pancreatic Cancer, Samantha B. Kemp, Marina Pasca di Magliano, and Howard C. Crawford

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PROMISE: a real-world clinical-genomic database to address knowledge gaps in prostate cancer, Vadim S. Koshkin, Vaibhav G. Patel, Alicia Ali, Mehmet A. Bilen, Deepak Ravindranathan, Joseph J. Park, Olesia Kellezi, Marcin Cieslik, Justin Shaya, Angelo Cabal, Landon Brown, Matthew Labriola, Laura S. Graham, Colin Pritchard, Abhishek Tripathi, Sanober Nusrat, Pedro Barata, Albert Jang, Shuang R. Chen, Rohan Garje, Luna Acharya, Clara Hwang, Amanda B. Pilling, William Oh, Tomi Jun, Divya Natesan, Chris Nguyen, Deepak Kilari, Michael Pierro, Bicky Thapa, Frank Cackowski, Alleda Mack, Elisabeth Heath, Catherine H. Marshall, Scott T. Tagawa, Susan Halabi, Michael T. Schweizer, Andrew Armstrong, Tanya Dorff, Ajjai Alva, and Rana McKay

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Association between ibrutinib treatment and hypertension, Dae Hyun Lee, Fahad Hawk, Kieun Seok, Matthew Gliksman, Josephine Emole, Isaac B. Rhea, Federico Viganego, Allan Welter-Frost, Merna Armanious, Bijal Shah, Juliio C. Chavez, Javier Pinilla-Ibarz, Matthew B. Schabath, and Michael Fradley

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The CoVID-TE risk assessment model for venous thromboembolism in hospitalized patients with cancer and COVID-19, Ang Li, Nicole M. Kuderer, Chih-Yuan Hsu, Yu Shyr, Jeremy L. Warner, Dimpy P. Shah, Vaibhav Kumar, Surbhi Shah, Amit A. Kulkarni, Julie Fu, Shuchi Gulati, Rebecca L. Zon, Monica Li, Aakash Desai, Pamela C. Egan, Ziad Bakouny, Devendra Kc, Clara Hwang, Imo J. Akpan, Rana R. McKay, Jennifer Girard, Andrew L. Schmidt, Balazs Halmos, Michael A. Thompson, Jaymin M. Patel, Nathan A. Pennell, Solange Peters, Amro Elshoury, Gilbero de Lima Lopes, Daniel G. Stover, Petros Grivas, Brian I. Rini, Corrie A. Painter, Sanjay Mishra, Jean M. Connors, Gary H. Lyman, and Rachel P. Rosovsky

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Disparities in Utilization of Autologous Stem Cell Transplantation as Consolidative Therapy for Multiple Myeloma: A Single Institution Retrospective Review, Oleksandra Lupak, Xiaoxia Han, Peter Xie, Kannan Thanikachalam, Hiba Jabbour-Aida, Shatha Farhan, and Josephine Emole

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Outcomes of in-hospital cardiopulmonary resuscitation for cardiac arrest in adult patients with metastatic solid cancers: A Nationwide Inpatient Sample database analysis from 2012 to 2014, Sindhu Malapati, Sunny R.K. Singh, Rohit Kumar, and Tarik Hadid

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What Matters Most? Predictors of Quality of Life and Life Satisfaction Among Young Breast Cancer Survivors, Kellie Martens, Gillian R. Ulrich, Krista W. Ranby, and Kristin Kilbourn

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Evolution of the Cancer Registrar in the Era of Informatics, Kelly W. Merriman, Ronda G. Broome, Giordana De Las Pozas, Lisa D. Landvogt, Ying Qi, and Judith Keating