Submissions from 2021
Tribbles 2 pseudokinase confers enzalutamide resistance in prostate cancer by promoting lineage plasticity, Jitender Monga, Indra Adrianto, Craig G. Rogers, Shirish M. Gadgeel, Dhananjay A. Chitale, Joshi J. Alumkal, Himisha Beltran, Amina Zoubeidi, and Jagadananda Ghosh
Adenoid cystic carcinoma of the labium oris with rare metastasis to the pleural cavity, Osama Mosalem, Anas Alsara, Fawzi Abu Rous, and Borys Hrinczenko
Impact of Oral Chemotherapy Management Program on Capecitabine Toxicity Management, Salin Nhean, Diana Kostoff, Jessica J. Yang, Vishnuprabha Vogel, and Igor I. Rybkin
Fludarabine and Melphalan Compared with Reduced Doses of Busulfan and Fludarabine Improve Transplantation Outcomes in Older Patients with Myelodysplastic Syndromes, Betül Oran, Kwang Woo Ahn, Caitrin Fretham, Amer Beitinjaneh, Asad Bashey, Attaphol Pawarode, Baldeep Wirk, Bart L. Scott, Bipin N. Savani, Christopher Bredeson, Daniel Weisdorf, David I. Marks, David Rizzieri, Edward Copelan, Gerhard C. Hildebrandt, Gregory A. Hale, Hemant S. Murthy, Hillard M. Lazarus, Jan Cerny, Jane L. Liesveld, Jean A. Yared, Jean Yves-Cahn, Jeffrey Szer, Leo F. Verdonck, Mahmoud Aljurf, Marjolein van der Poel, Mark Litzow, Matt Kalaycio, Michael R. Grunwald, Miguel Angel Diaz, Mitchell Sabloff, Mohamed A. Kharfan-Dabaja, Navneet S. Majhail, Nosha Farhadfar, Ran Reshef, Richard F. Olsson, Robert Peter Gale, Ryotaro Nakamura, Sachiko Seo, Saurabh Chhabra, Shahrukh Hashmi, Shatha Farhan, Siddhartha Ganguly, Sunita Nathan, Taiga Nishihori, Tania Jain, Vaibhav Agrawal, Ulrike Bacher, Uday Popat, and Wael Saber
Thrombocytapheresis for acquired von Willebrand syndrome in a patient with essential thrombocythemia and recent multivisceral transplantation, Oluwayomi Oyedeji, Jawad Sheqwara, Ifeoma Onwubiko, Ileana Lopez-Plaza, Shunji Nagai, and Zaher K. Otrock
Androgen receptor negatively regulates mitotic checkpoint signaling to induce docetaxel resistance in castration-resistant prostate cancer, Amanda B. Pilling, Sahn-Ho Kim, and Clara Hwang
Bone Metastases, Skeletal-Related Events, and Survival in Patients With Metastatic Non-Small Cell Lung Cancer Treated With Immune Checkpoint Inhibitors, Angel Qin, Songzhu Zhao, Abdul Miah, Lai Wei, Sandipkumar Patel, Andrew Johns, Madison Grogan, Erin M. Bertino, Kai He, Peter G. Shields, Gregory P. Kalemkerian, Shirish M. Gadgeel, Nithya Ramnath, Bryan J. Schneider, Khaled A. Hassan, Nicholas Szerlip, Zoey Chopra, Sara Journey, Jessica Waninger, Daniel Spakowicz, David P. Carbone, Carolyn J. Presley, Gregory A. Otterson, Michael D. Green, and Dwight H. Owen
Activity and Safety of Mobocertinib (TAK-788) in Previously Treated Non-Small Cell Lung Cancer With EGFR Exon 20 Insertion Mutations From a Phase 1/2 Trial, Gregory J. Riely, Joel W. Neal, D. Ross Camidge, Alexander I. Spira, Zofia Piotrowska, Daniel B. Costa, Anne S. Tsao, Jyoti D. Patel, Shirish M. Gadgeel, Lyudmila Bazhenova, Viola W. Zhu, Howard L. West, Tarek Mekhail, Ryan D. Gentzler, Danny Nguyen, Sylvie Vincent, Steven Zhang, Jianchang Lin, Veronica Bunn, Shu Jin, Shuanglian Li, and Pasi A. Janne
Association Between Androgen Deprivation Therapy and Mortality Among Patients With Prostate Cancer and COVID-19, Andrew L. Schmidt, Matthew D. Tucker, Ziad Bakouny, Chris Labaki, Chih-Yuan Hsu, Yu Shyr, Andrew J. Armstrong, Tomasz M. Beer, Ragneel R. Bijjula, Mehmet A. Bilen, Cindy F. Connell, Scott Joseph Dawsey, Bryan Faller, Xin Gao, Benjamin A. Gartrell, David Gill, Shuchi Gulati, Susan Halabi, Clara Hwang, Monika Joshi, Ali Raza Khaki, Harry Menon, Michael J. Morris, Matthew Puc, Karen B. Russell, Neil J. Shah, Nima Sharifi, Justin Shaya, Michael T. Schweizer, John Steinharter, Elizabeth M. Wulff-Burchfield, Wenxin Xu, Jay Zhu, Sanjay Mishra, Petros Grivas, Brian I. Rini, Jeremy Lyle Warner, Tian Zhang, Toni K. Choueiri, Shilpa Gupta, and Rana R. McKay
Natural history study of factor IX deficiency with focus on treatment and complications (B-Natural), Amy D. Shapiro, Margaret V. Ragni, Munira Borhany, Yasmina L. Abajas, Michael D. Tarantino, Katharina Holstein, Stacy E. Croteau, Riana Liesner, Cristina Tarango, Manuela Carvalho, Catherine McGuinn, Eva Funding, Christine L. Kempton, Christoph Bidlingmaier, Alice Cohen, Johannes Oldenburg, Susan Kearney, Christine Knoll, Philip Kuriakose, Suchitra Acharya, Ulrike M. Reiss, Roshni Kulkarni, Michelle Witkop, Stefan Lethagen, Sharyne Donfield, Petra LeBeau, Erik Berntorp, and Jan Astermark
NCDB analysis of melanoma 2004–2015: Epidemiology and outcomes by subtype, sociodemographic factors impacting clinical presentation, and real‐world survival benefit of immunotherapy approval, Sunny R.K. Singh, Sindhu J. Malapati, Rohit Kumar, Christopher Willner, and Ding Wang
First-in-Class Anti-immunoglobulin-like Transcript 4 Myeloid-Specific Antibody MK-4830 Abrogates a PD-1 Resistance Mechanism in Patients with Advanced Solid Tumors, Lillian L. Siu, Ding Wang, John Hilton, Ravit Geva, Drew Rasco, Ruth Perets, Anson K. Abraham, Douglas C. Wilson, Julia F. Markensohn, Jared Lunceford, Leah Suttner, Shabana Siddiqi, Rachel A. Altura, and Corinne Maurice-Dror
Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1, in Patients with Esophageal Adenocarcinoma: Results from a Phase 1 Cohort, Benjamin Tan, Adnan Khattak, Enriqueta Felip, Karen Kelly, Patricia Rich, Ding Wang, Christoph Helwig, Isabelle Dussault, Laureen S. Ojalvo, and Nicolas Isambert
Association of Convalescent Plasma Therapy With Survival in Patients With Hematologic Cancers and COVID-19, Michael A. Thompson, Jeffrey P. Henderson, Pankil K. Shah, Samuel M. Rubinstein, Michael J. Joyner, Toni K. Choueiri, Daniel B. Flora, Elizabeth A. Griffiths, Anthony P. Gulati, Clara Hwang, Vadim S. Koshkin, Esperanza B. Papadopoulos, Elizabeth V. Robilotti, Christopher T. Su, Elizabeth M. Wulff-Burchfield, Zhuoer Xie, Peter Paul Yu, Sanjay Mishra, Jonathon W. Senefeld, Dimpy P. Shah, and Jeremy L. Warner
Clinical Efficacy of Enzalutamide vs Bicalutamide Combined With Androgen Deprivation Therapy in Men With Metastatic Hormone-Sensitive Prostate Cancer: A Randomized Clinical Trial, Ulka N. Vaishampayan, Lance K. Heilbrun, Paul Monk, Sheela Tejwani, Guru Sonpavde, Clara Hwang, Daryn Smith, Pallavi Jasti, Kimberlee Dobson, Brenda Dickow, Elisabeth I. Heath, Louie Semaan, Michael L. Cher, Joseph A. Fontana, and Sreenivasa Chinni
KDM6A Regulates Cell Plasticity and Pancreatic Cancer Progression by Non-Canonical Activin Pathway, Zhujun Yi, Shanqiao Wei, Lin Jin, Sivakumar Jeyarajan, Jing Yang, Yumei Gu, Hong Sun Kim, Shula Schechter, Shuang Lu, Michelle T. Paulsen, Karan Bedi, Ishwarya Venkata Narayanan, Mats Ljungman, Howard C. Crawford, Marina Pasca di Magliano, Kai Ge, Yali Dou, and Jiaqi Shi
Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma Treated With Liposomal Irinotecan, Kenneth H. Yu, Andrew E. Hendifar, Olatunji B. Alese, Amber Draper, Maen Abdelrahim, Ethan Burns, Gazala Khan, Paul Cockrum, Rachel H. Bhak, Catherine Nguyen, Maral DerSarkissian, Mei Sheng Duh, and Nathan Bahary
Submissions from 2020
Avelumab as second-line therapy for metastatic, platinum-treated urothelial carcinoma in the phase Ib JAVELIN Solid Tumor study: 2-year updated efficacy and safety analysis, Andrea B. Apolo, John A. Ellerton, Jeffrey R. Infante, Manish Agrawal, Michael S. Gordon, Raid Aljumaily, Theodore Gourdin, Luc Dirix, Keun-Wook Lee, Matthew H. Taylor, Patrick Schöffski, Ding Wang, Alain Ravaud, Juliane Manitz, Gregory Pennock, Mary Ruisi, James L. Gulley, and Manish R. Patel
Heterogeneity at the invasion front of triple negative breast cancer cells, Koh Meng Aw Yong, Peter J. Ulintz, Sara Caceres, Xu Cheng, Liwei Bao, Zhifen Wu, Evelyn M. Jiagge, and Sofia D. Merajver
Hematology/Oncology Fellowship Emergency Restructuring in Response to the COVID-19 Pandemic—Henry Ford Hospital, Michigan, Nino Balanchivadze and Vijayalakshmi Donthireddy
Impact of COVID-19 Infection on 24 Patients with Sickle Cell Disease One Center Urban Experience, Detroit, MI, USA, Nino Balanchivadze, Adam A. Kudirka, Sally FK Askar, Khaled Almadhoun, Philip Kuriakose, Raef Fadel, and Vrushali Dabak
American Radium Society Appropriate Use Criteria: Radiation Therapy for Limited-Stage SCLC 2020, Stephen G. Chun, Charles B. Simone, Arya Amini, Indrin J. Chetty, Jessica Donington, Martin J. Edelman, Kristin A. Higgins, Larry L. Kestin, Benjamin Movsas, George B. Rodrigues, Kenneth E. Rosenzweig, Ben J. Slotman, Igor I. Rybkin, Andrea Wolf, and Joe Y. Chang
Synthesis, Cytotoxicity, and Genotoxicity of 10-Aza-9-oxakalkitoxin, an N,N,O-Trisubstituted Hydroxylamine Analog, or Hydroxalog, of a Marine Natural Product, Sandeep Dhanju, Kapil Upadhyaya, Christopher A. Rice, Scott D. Pegan, Joe Media, Frederick A. Valeriote, and David Crich
Olaparib and durvalumab in patients with germline BRCA-mutated metastatic breast cancer (MEDIOLA): an open-label, multicentre, phase 1/2, basket study, Susan M. Domchek, Sophie Postel-Vinay, Seock-Ah Im, Yeon Hee Park, Jean-Pierre Delord, Antoine Italiano, Jerome Alexandre, Benoit You, Sara Bastian, Matthew G Krebs, Ding Wang, Saiama N. Waqar, Mark Lanasa, Joon Rhee, Haiyan Gao, Vidalba Rocher-Ros, Emma V. Jones, Sakshi Gulati, Anna Coenen-Stass, Iwanka Kozarewa, Zhongwu Lai, Helen K. Angell, Laura Opincar, Pia Herbolsheimer, and Bella Kaufman
Using whole breast ultrasound tomography to improve breast cancer risk assessment: A novel risk factor based on the quantitative tissue property of sound speed, Neb Duric, Mark Sak, Shaoqi Fan, Ruth M. Pfeiffer, Peter J. Littrup, Michael S. Simon, David H. Gorski, Haythem Y. Ali, Kristen S. Purrington, Rachel F. Brem, Mark E. Sherman, and Gretchen L. Gierach
A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry, Zhaohui Du, Niels Weinhold, Gregory C. Song, Kristin A. Rand, David J. Van Den Berg, Amie E. Hwang, Xin Sheng, Victor Hom, Sikander Ailawadhi, Ajay K. Nooka, Seema Singhal, Karen Pawlish, Edward S. Peters, Cathryn Bock, Ann Mohrbacher, Alexander Stram, Sonja I. Berndt, William J. Blot, Graham Casey, Victoria L. Stevens, Rick Kittles, Phyllis J. Goodman, W R. Diver, Anselm Hennis, Barbara Nemesure, Eric A. Klein, Benjamin A. Rybicki, Janet L. Stanford, John S. Witte, Lisa Signorello, Esther M. John, Leslie Bernstein, Antoinette M Stroup, Owen W Stephens, Maurizio Zangari, Frits Van Rhee, Andrew Olshan, Wei Zheng, Jennifer J Hu, Regina Ziegler, Sarah J Nyante, Sue Ann Ingles, Michael F Press, John David Carpten, Stephen J Chanock, Jayesh Mehta, Graham A Colditz, Jeffrey Wolf, Thomas G Martin, Michael Tomasson, Mark A Fiala, Howard Terebelo, Nalini Janakiraman, Laurence Kolonel, Kenneth C Anderson, Loic Le Marchand, Daniel Auclair, Brian C-H Chiu, Elad Ziv, Daniel Stram, Ravi Vij, Leon Bernal-Mizrachi, Gareth J Morgan, Jeffrey A Zonder, Carol Ann Huff, Sagar Lonial, Robert Z Orlowski, David V Conti, Christopher A Haiman, and Wendy Cozen
Phase II Study of a Temozolomide-Based Chemo-radiotherapy Regimen for High Risk Low-Grade Gliomas: Long-term Results of Radiation Therapy Oncology Group (RTOG) 0424, Barbara J. Fisher, Stephanie L. Pugh, David R. Macdonald, Arnab Chakravatri, Glenn J. Lesser, Sherry Fox, C L. Rogers, Maria Werner-Wasik, Thomas Doyle, Jean-Paul Bahary, John B. Fiveash, Joseph A. Bovi, Steven P. Howard, Hsiang-Hsuan Michael Yu, David D'Souza, Nadia N. Laack, Igor J. Barani, Young Kwok, Daniel R. Wahl, Jon F. Strasser, Minhee Won, and Minesh P. Mehta
Electrocardiographic Changes Associated With Ibrutinib Exposure, Michael G. Fradley, Allan Welter-Frost, Matthew Gliksman, Josephine Emole, Federico Viganego, Dae Hyun Lee, Bijal Shah, Julio C. Chavez, Javier Pinilla-Ibarz, and Matthew B. Schabath
Neratinib plus Cetuximab in Quadruple WT (KRAS, NRAS, BRAF, PIK3CA) Metastatic Colorectal Cancer Resistant to Cetuximab or Panitumumab: NSABP FC-7, A Phase Ib Study, Samuel A. Jacobs, James J. Lee, Thomas J. George, James L. Wade, Philip J. Stella, Ding Wang, Ashwin Sama, Fanny Piette, Katherine L Pogue-Geile, Rim S. Kim, Patrick G. Gavin, Corey Lipchik, Huichen Feng, Ying Wang, Melanie Finnigan, Brian Kiesel, Jan H. Beumer, Norman Wolmark, Peter C. Lucas, Carmen J. Allegra, and Ashok Srinivasan
Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8, Tyler A. Johnson, Joseph D. Morris, David A. Coppage, Colon V. Cook, Lauren N. Persi, Marcos A. Ogarrio, Taylor C. Garcia, Nicole L. McIntosh, Erin P. McCauley, Joe Media, Mani Maheshwari, Frederick A. Valeriote, Jiajiu Shaw, and Phillip Crews
Is the HERV-K HML-2 Xq2133, an endogenous retrovirus mutated by gene conversion of chromosome X in a subset of African populations, associated with human breast cancer?, Mark H. Kaplan, Rafael Contreras-Galindo, Evelyn M. Jiagge, Sofia D. Merajver, Lisa Newman, Galya Bigman, Michael H. Dosik, Ganesh S. Palapattu, Javed Siddiqui, Arul M. Chinnaiyan, Sally Adebamowo, and Clement Adebamowo
BRAINSTORM: A Multi-Institutional Phase I/II Study of RRx-001 in Combination with Whole Brain Radiation Therapy for Patients with Brain Metastases, Michelle M Kim, Hemant A Parmar, Matthew Schipper, Theresa Devasia, Madhava P Aryal, Santosh Kesari, Steven O'Day, Aki Morikawa, Daniel E Spratt, Larry Junck, Aaron Mammoser, James A Hayman, Theodore S Lawrence, Christina I Tsien, Robert Aiken, Sharad Goyal, Nacer Abrouk, Malcolm Trimble, Yue Cao, and Christopher D. Lao
Incidence and outcomes of heparin-induced thrombocytopenia in solid malignancy: an analysis of the National Inpatient Sample Database, Rohit Kumar, Shruti Bhandari, Sukhpreet RK Singh, Sindhu Malapati, and Kamila I. Cisak
Poroid Hidradenoma; a Benign Lesion Masking as Malignant Breast Tumor, Hassan Liaqat, Mohammad Ammad Ud Din, and Devin Malik
Real-world effectiveness of the pegfilgrastim on-body injector in preventing severe neutropenia, Lucas G. Maahs, Amy Tang, Zaid Al-Saheli, Brigid Jacob, Rishika Polasani, and Clara Hwang
Atezolizumab Versus Docetaxel in Pretreated Patients With NSCLC: Final Results From the Randomized Phase 2 POPLAR and Phase 3 OAK Clinical Trials, Julien Mazieres, Achim Rittmeyer, Shirish M. Gadgeel, Toyoaki Hida, David R. Gandara, Diego L. Cortinovis, Fabrice Barlesi, Wei Yu, Christina Matheny, Marcus Ballinger, and Keunchil Park
Outcomes According to ALK Status Determined by Central Immunohistochemistry or Fluorescence In Situ Hybridization in Patients With ALK-Positive NSCLC Enrolled in the Phase 3 ALEX Study, Tony Mok, Solange Peters, D. Ross Camidge, Johannes Noé, Shirish M. Gadgeel, Sai-Hong I. Ou, Dong-Wan Kim, Krzysztof Konopa, Emanuela Pozzi, Ting Liu, Isabell R. Loftin, Crystal Williams, and Alice T. Shaw
Bilateral breast masses as a presentation for T-cell acute lymphoblastic leukaemia, Osama Mosalem, Fawzi Abu Rous, Ahmed Elshafie, and Daniel Isaac
Pulmonary embolism as the primary presentation of IgA vasculitis, Osama Mosalem, Nora Hernandez Garcilazo, Yehia Saleh, and Fawzi Abu Rous
A user's guide to lorlatinib, Misako Nagasaka, Yubin Ge, Ammar Sukari, Geetika Kukreja, and Sai-Hong Ignatius Ou
Predictors of response and outcome of patients with acquired haemophilia A, Ifeoma Onwubiko, Gary Kasperek, Rosarina A. Laforest, Samuel G. Philip, Philip Kuriakose, and Zaher K. Otrock
Cold agglutinin disease and autoimmune hemolytic anemia with pulmonary embolism as a presentation of COVID-19 infection, Neha R. Patil, Erica S. Herc, and Marian R. Girgis
Exceptional Response to A Single Cycle of Immunotherapy in a Lynch Syndrome Patient with Metastatic Pancreatic Adenocarcinoma, Neha R. Patil and Gazala N. Khan
Primary Pleural Extranodal Marginal Zone Lymphoma Presenting as Bilateral Chylothorax, Thushara Paul, Dhiraj K. Yadav, Mohamed Alhamar, and Vrushali Dabak
Molecular therapeutic targets in non-small cell lung cancer, Kamya Sankar, Shirish M. Gadgeel, and Angel Qin
A Versatile Chemoenzymatic Synthesis for the Discovery of Potent Cryptophycin Analogs, Jennifer J Schmidt, Yogan Khatri, Scott I Brody, Catherine Zhu, Halina Pietraszkiewicz, Frederick A. Valeriote, and David H. Sherman
Toxicity in combination immune checkpoint inhibitor and radiation therapy: a systematic review and meta-analysis, Congzhou M Sha, Eric J. Lehrer, Clara Hwang, Daniel M. Trifiletti, Heath B. Mackley, Joseph J. Drabick, and Nicholas G. Zaorsky
Desperate times, desperate measures: successful use of chemotherapy in treatment of haemophagocytic lymphohistiocytosis (HLH) due to disseminated histoplasmosis, Sunny RK Singh, Kannan Thanikachalam, and Vijayalakshmi Donthireddy
COVID-19 and Cancer: Lessons Learnt from a Michigan Hotspot, Sunny RK Singh, Kannan Thanikachalam, Hiba Jabbour Aida, Laila M. Poisson, and Gazala Khan
Pseudo-Thrombocytosis Caused by Extreme Microcytosis in a Patient with Alpha Thalassemia Trait, Alexander A. Slota, Devin Malik, and Diane Hall
Optimal Donor for African Americans with Hematologic Malignancy: HLA-Haploidentical Relative or Umbilical Cord Blood Transplant, Scott R. Solomon, Andrew St. Martin, Mei-Jie Zhang, Karen Ballen, Asad Bashey, Minoo Battiwalla, Lee Ann Baxter-Lowe, Claudio Brunstein, Saurabh Chhabra, Miguel Perez, Ephraim J. Fuchs, Siddhartha Ganguly, Nancy Hardy, Peiman Hematti, Joseph McGuirk, Edward Peres, Olle Ringden, David Rizzieri, Rizwan Romee, Melhem Solh, David Szwajcer, Marjolein van der Poel, Edmund Waller, Basem M. William, and Mary Eapen
Brief Report: Randomized Phase 2 Studies of Checkpoint Inhibitors Alone or in Combination with Pegilodecakin in Patients with Metastatic Non-Small-Cell Lung Cancer (CYPRESS-1 and CYPRESS-2), David Spigel, Robert Jotte, John Nemunaitis, Merrill Shum, Jeffrey Schneider, Jerome Goldschmidt, Jennifer Eisenstein, David Berz, Lasika Seneviratne, Matei Socoteanu, Viralkumar Bhanderi, Kartik Konduri, Meng Xia, Hong Wang, Rebecca R Hozak, Ivelina Gueorguieva, David Ferry, Leena Gandhi, Bo H Chao, and Igor Rybkin
The role of immune checkpoint inhibitors in anaplastic thyroid cancer (Case Series), Ammar Sukari, Geetika Kukreja, Misako Nagasaka, Mohammad K. Shukairy, George Yoo, Ho-Sheng Lin, Jeffrey Hotaling, and Harold Kim
Disparities in the Uptake of Telemedicine During the COVID-19 Surge in a Multidisciplinary Head and Neck Cancer Population by Patient Demographic Characteristics and Socioeconomic Status, Samantha Tam, Vivian Wu, Amy M. Williams, Marian R. Girgis, Jawad Z. Sheqwara, Farzan Siddiqui, and Steven S. Chang
Neoadjuvant Phase II Trial of Chemoradiotherapy in Patients With Resectable and Borderline Resectable Pancreatic Cancer, Kannan Thanikachalam, Vijay Damarla, Trevor Seixas, Irina Dobrosotskaya, Ira Wollner, David Kwon, Kenneth Winters, Mohammad Raoufi, Jia Li, Farzan Siddiqui, and Gazala Khan
Efficacy and safety of first-line avelumab in patients with advanced non-small cell lung cancer: results from a phase Ib cohort of the JAVELIN Solid Tumor study, Claire F. Verschraegen, Guy Jerusalem, Edward F. McClay, Nicholas Iannotti, Charles H. Redfern, Jaafar Bennouna, Franklin L. Chen, Karen Kelly, Janice Mehnert, John C. Morris, Matthew Taylor, David Spigel, Ding Wang, Hans Juergen Grote, Dongli Zhou, Neru Munshi, Marcis Bajars, and James L. Gulley
Phase 1 study of mTORC1/2 inhibitor sapanisertib (TAK-228) in advanced solid tumours, with an expansion phase in renal, endometrial or bladder cancer, Martin H. Voss, Michael S. Gordon, Monica Mita, Brian Rini, Vicky Makker, Teresa Macarulla, David C. Smith, Andrés Cervantes, Igor Puzanov, Roberto Pili, Ding Wang, Shadia Jalal, Shubham Pant, Manish R. Patel, Rachel L. Neuwirth, Aaron Enke, Yaping Shou, Farhad Sedarati, Douglas V. Faller, and Howard A. Burris
Variability in Cytogenetic Testing for Multiple Myeloma: A Comprehensive Analysis From Across the United States, Yang Yu, Niquelle Brown Wade, Amie E. Hwang, Ajay K. Nooka, Mark A. Fiala, Ann Mohrbacher, Edward S. Peters, Karen Pawlish, Cathryn Bock, David J. Van Den Berg, Kristin A. Rand, Daniel Stram, David V. Conti, Daniel Auclair, Graham A. Colditz, Jayesh Mehta, Christopher A. Haiman, Howard Terebelo, Nalini Janakiraman, Seema Singhal, Brian Chiu, Ravi Vij, Leon Bernal-Mizrachi, Jeffrey A. Zonder, Carol A. Huff, Sagar Lonial, Robert Z. Orlowski, Wendy Cozen, and Sikander Ailawadhi
Submissions from 2019
Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents, Jehad Almaliti, Bailey Miller, Halina Pietraszkiewicz, Evgenia Glukhov, C B. Naman, Toni Kline, Jeffrey Hanson, Xiaofan Li, Sihong Zhou, Frederick A. Valeriote, and William H. Gerwick
Rates of deep molecular response by digital and conventional PCR with frontline nilotinib in newly diagnosed chronic myeloid leukemia: a landmark analysis, Jesus G. Berdeja, Michael C. Heinrich, Shaker R. Dakhil, Stuart L. Goldberg, Martha Wadleigh, Philip Kuriakose, Jorge Cortes, Jerald Radich, Bret Helton, David Rizzieri, Carole Paley, Ilva Dautaj, and Michael J. Mauro
Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp, Eduardo JE Caro-Diaz, Frederick A. Valeriote, and William H. Gerwick
A phase Ib study of utomilumab (PF-05082566) in combination with mogamulizumab in patients with advanced solid tumors, Ezra EW Cohen, Michael J. Pishvaian, Dale R. Shepard, Ding Wang, Jared Weiss, Melissa L. Johnson, Christine H. Chung, Ying Chen, Bo Huang, Craig B. Davis, Francesca Toffalorio, Aron Thall, and Steven F. Powell
The effects of lapatinib on cardiac repolarization: results from a placebo controlled, single sequence, crossover study in patients with advanced solid tumors, Shodeinde A. Coker, Herbert I. Hurwitz, Sunil Sharma, Ding Wang, Pierre Jordaan, Juan P. Zarate, and Lionel D. Lewis
A Phase I/Ib Trial of the VEGFR-Sparing Multikinase RET Inhibitor RXDX-105, Alexander Drilon, Siqing Fu, Manish R. Patel, Marwan Fakih, Ding Wang, Anthony J. Olszanski, Daniel Morgensztern, Stephen V. Liu, Byoung C. Cho, Lyudmila Bazhenova, Cristina P. Rodriguez, Robert C. Doebele, Antoinette Wozniak, Karen L. Reckamp, Tara Seery, Petros Nikolinakos, Zheyi Hu, Jennifer W. Oliver, Denise Trone, Katherine McArthur, Rupal Patel, Pratik S. Multani, and Myung-Ju Ahn
Rates and Risk of Atrial Arrhythmias in Patients Treated With Ibrutinib Compared With Cytotoxic Chemotherapy, Michael G. Fradley, Matthew Gliksman, Josephine Emole, Federico Viganego, Isaac Rhea, Allan Welter-Frost, Merna Armanious, Dae-Hyun Lee, Christine Walko, Bijal Shah, Julio C. Chavez, Howard McLeod, Javier Pinilla-Ibarz, and Matthew B. Schabath
The KRAS, Jill Hallin, Lars D. Engstrom, Lauren Hargis, Andrew Calinisan, Ruth Aranda, David M. Briere, Niranjan Sudhakar, Vickie Bowcut, Brian R. Baer, Joshua A. Ballard, Michael R. Burkard, Jay B. Fell, John P. Fischer, Guy P. Vigers, Yaohua Xue, Sole Gatto, Julio Fernandez-Banet, Adam Pavlicek, Karen Velastagui, Richard C. Chao, Jeremy Barton, Mariaelena Pierobon, Elisa Baldelli, Emanuel F. Patricoin, Douglas P. Cassidy, Matthew A. Marx, I Rybkin, Melissa L. Johnson, Sai-Hong I. Ou, Piro Lito, Kyriakos P. Papadopoulos, Pasi A. Jänne, Peter Olson, and James G Christensen
A Noninvasive Blood-based Combinatorial Proteomic Biomarker Assay to Detect Breast Cancer in Women over age 50 with BI-RADS 3, 4, or 5 Assessment, Meredith C. Henderson, Michael Silver, Quynh Tran, Elias E. Letsios, Rao Mulpuri, David E. Reese, Ana P. Lourenco, Joshua LaBaer, Karen S. Anderson, Josie Alpers, Carrie Costantini, Nitin Rohatgi, Haythem Y. Ali, Karen Baker, Donald W. Northfelt, Karthik Ghosh, Stephen R. Grobmyer, Winnie Polen, and Judith K. Wolf
Evaluation of a Multidisciplinary Team Approach for Generating Survivorship Care Plan Treatment Summaries in Patients With Breast Cancer, Tommy Ivanics, Erica Proctor, Yalei Chen, Haythem Y. Ali, Dawn Severson, Hassan Nasser, Sonja Colbert, Laura L. Susick, Eleanor Walker, Lindsay Petersen, Jessica Bensenhaver, Randa Loutfi, S David Nathanson, and Lisa A. Newman
Atypical Chemokine Receptor 1 (DARC/ACKR1) in Breast Tumors Is Associated with Survival, Circulating Chemokines, Tumor-Infiltrating Immune Cells, and African Ancestry, Brittany D. Jenkins, Rachel N. Martini, Rupali Hire, Andrea Brown, Briana Bennett, I'nasia Brown, Elizabeth W. Howerth, Mary Egan, Jamie Hodgson, Clayton Yates, Rick Kittles, Dhananjay A. Chitale, Haythem Y. Ali, S David Nathanson, Petros Nikolinakos, Lisa A. Newman, Michele Monteil, and Melissa B. Davis
Evaluation of the impact of thyroiditis development in patients receiving immunotherapy with programmed cell death-1 inhibitors, Matthew Lei, Angela Michael, Seema Patel, and Ding Wang
The role of a low erythropoietin level for the polycythemia vera diagnosis, Oleksandra Lupak, Xiaoxia Han, Peter Xie, Sharmeen Mahmood, Hadi Mohammed, and Vijayalakshmi Donthireddy
Class III β-tubulin expression as a predictor of docetaxel-resistance in metastatic castration-resistant prostate cancer, Lucas G. Maahs, Bertha E. Sanchez, Nilesh S. Gupta, Meredith Van Harn, Evelyn R. Barrack, Prem-Veer Reddy, and Clara Hwang
RRx-001 followed by platinum plus etoposide in patients with previously treated small-cell lung cancer, Daniel Morgensztern, Michal Rose, Saiama N. Waqar, John Morris, Patrick C. Ma, Thomas Reid, Christina E. Brzezniak, Karen G. Zeman, Arvinda Padmanabhan, JoAnn Hirth, Alexander I Spira, Jane B. Trepel, and Sukhmani K. Padda
Targeting prosurvival BCL2 signaling through Akt blockade sensitizes castration-resistant prostate cancer cells to enzalutamide, Amanda B. Pilling and Clara Hwang
Castration-resistant prostate cancer: Androgen receptor inactivation induces telomere DNA damage, and damage response inhibition leads to cell death, Vidyavathi Reddy, Asm Iskander, Clara Hwang, George Divine, Mani Menon, Evelyn R. Barrack, G Prem-Veer Reddy, and Sahn-Ho Kim
US Cancer Centers of Excellence Strategies for Increased Inclusion of Racial and Ethnic Minorities in Clinical Trials, Jeanne M. Regnante, Nicole A. Richie, Lola Fashoyin-Aje, Michelle Vichnin, Marvella Ford, Upal B. Roy, Kenneth Turner, Laura L. Hall, Evelyn Gonzalez, Nestor Esnaola, Luther T. Clark, Homer C. Adams, Olatunji B. Alese, Keerthi Gogineni, Lorna McNeill, Daniel Petereit, Ify Sargeant, Julie Dang, Coleman Obasaju, Quita Highsmith, Simon C. Lee, Spencer C. Hoover, Erin L. Williams, and Moon S. Chen
Impact of T Cell Dose on Outcome of T Cell-Replete HLA-Matched Allogeneic Peripheral Blood Stem Cell Transplantation, Ayman Saad, Lawrence Lamb, Tao Wang, Michael T. Hemmer, Stephen Spellman, Daniel Couriel, Amin Alousi, Joseph Pidala, Hisham Abdel-Azim, Vaibhav Agrawal, Mahmoud Aljurf, Amer M. Beitinjaneh, Vijaya R. Bhatt, David Buchbinder, Michael Byrne, Jean-Yves Cahn, Mitchell Cairo, Paul Castillo, Saurabh Chhabra, Miguel A. Diaz, Shatha Farhan, Yngvar Floisand, Hadar A. Frangoul, Shahinaz M. Gadalla, James Gajewski, Robert P. Gale, Manish Gandhi, Usama Gergis, Betty K. Hamilton, Peiman Hematti, Gerhard C. Hildebrandt, Rammurti T. Kamble, Abraham S Kanate, Pooja Khandelwal, Aleksandr Lazaryn, Margaret MacMillan, David I Marks, Rodrigo Martino, Parinda A Mehta, Taiga Nishihori, Richard F Olsson, Sagar S Patel, Muna Qayed, Hemalatha G Rangarajan, Ran Reshef, Olle Ringden, Bipin N Savani, Harry C Schouten, Kirk R Schultz, Sachiko Seo, Brian C Shaffer, Melhem Solh, Takanori Teshima, Alvaro Urbano-Ispizua, Leo F Verdonck, Ravi Vij, Edmund K Waller, Basem William, Baldeep Wirk, Jean A Yared, Lolie C Yu, Mukta Arora, and Shahrukh Hashmi
Colorectal Cancer and Nutrition, Kannan Thanikachalam and Gazala Khan
Development of an algorithm for the systematic evaluation of patients with suspected heparin-induced thrombocytopenia, Julie Thomson, Philip Kuriakose, Long To, Michael Peters, and James Kalus
A rare case of follicular lymphoma transformed to a high-grade B-cell lymphoma in orbit, Raju K. Vaddepally, Amal Hejab, Vrushali Dabak, and Madhu P. Menon
Computationally Assisted Discovery and Assignment of a Highly Strained and PANC-1 Selective Alkaloid from Alaska's Deep Ocean, Yike Zou, Xiaojuan Wang, James Sims, Bin Wang, Pankaj Pandey, Colin L. Welsh, Robert P. Stone, Mitchell A. Avery, Robert J. Doerksen, Daneel Ferreira, Clemens Anklin, Frederick A. Valeriote, Michelle Kelly, and Mark T. Hamann
Submissions from 2018
A Lesion on the Scalp, Zaid Abdel-Rahman, Kedar Inamdar, and Haythem Y. Ali
Phase 1 study of seviteronel, a selective CYP17 lyase and androgen receptor inhibitor, in women with estrogen receptor-positive or triple-negative breast cancer, Aditya Bardia, Ayca Gucalp, Noashir DaCosta, Nashat Gabrail, Michael Danso, Haythem Y. Ali, Kimberly L. Blackwell, Lisa A. Carey, Joel R. Eisner, Edwina S. Baskin-Bey, and Tiffany A. Traina
Harnessing a Different Dependency: How to Identify and Target Androgen Receptor-Positive Versus Quadruple-Negative Breast Cancer, Jessica L. Christenson, Jane B. Trepel, Haythem Y. Ali, Sunmin Lee, Joel R. Eisner, Edwina S. Baskin-Bey, Anthony D. Elias, and Jennifer K. Richer
Venetoclax, bendamustine, and rituximab in patients with relapsed or refractory NHL: a phase Ib dose-finding study, S de Vos, L J. Swinnen, Ding Wang, E Reid, N Fowler, J Cordero, M Dunbar, S H. Enschede, C Nolan, A M. Petrich, J A. Ross, A H. Salem, M Verdugo, S Agarwal, L Zhou, M Kozloff, L J. Nastoupil, and C R. Flowers
Unexplained pancytopenia in acute myeloid leukemia treatment, Daniel Ezekwudo, Oleksandra Lupak, Raju Vaddepally, Bolanle Gbadamosi, and Philip Kuriakose
Phase 1b investigation of the MEK inhibitor binimetinib in patients with advanced or metastatic biliary tract cancer, R S. Finn, D H. Ahn, M M. Javle, B R. Tan, C D. Weekes, J C. Bendell, A Patnaik, Gazala Khan, D Laheru, R Chavira, J Christy-Bittel, E Barrett, M B. Sawyer, and Tanios S. Bekaii-Saab
A Retrospective Study Analyzing the Appropriateness of Initial Treatment of, Aaron Fisher, Pradeep Khanal, Ewa Gniado, Leila Khaddour, Molly Orosey, Ismail Hader, Siddhartha Yadav, and Alexandra Halalau
Nab-paclitaxel-based therapy in underserved patient populations: The aboundPs2 study in patients with nsclc and a performance status of 2, Ajeet Gajra, Nagla A. Karim, Deborah A. Mulford, Liza C. Villaruz, Marc R. Matrana, Haythem Y. Ali, Edgardo S. Santos, Tymara Berry, Teng J. Ong, Alexandra Sanford, Katayoun Amiri, and David R. Spigel
Management of haemophilia carriers around the time of their delivery: Phenotypic variation requiring customization of management, M R. Girgis, L Gusba, and Philip Kuriakose
Genitourinary Pathology Reporting Parameters Most Relevant to the Medical Oncologist, Clara Hwang
Enrichment and mutation detection of circulating tumor cells from blood samples, Ruqin Kou, Jian Zhao, Priya Gogoi, Shannon Carskadon, Will Chow, Clara Hwang, Nallasivam Palanisamy, Conrad Leung, and Yixin Wang
Graft-versus-host disease in recipients of male unrelated donor compared with parous female sibling donor transplants, Anita J. Kumar, Soyoung Kim, Michael T. Hemmer, Mukta Arora, Stephen R. Spellman, Joseph A. Pidala, Daniel R. Couriel, Amin M. Alousi, Mahmoud D. Aljurf, Jean-Yves Cahn, Mitchell S. Cairo, Corey S. Cutler, Shatha Farhan, Usama Gergis, Gregory A. Hale, Shahrukh K. Hashmi, Yoshihiro Inamoto, Rammurti T. Kamble, Mohamed A. Kharfan-Dabaja, Margaret L. MacMillan, David I. Marks, Hideki Nakasone, Maxim Norkin, Muna Qayed, Olle Ringden, Harry C. Schouten, Kirk R. Schultz, Melhem M. Solh, Takanori Teshima, Alvaro Urbano-Ispizua, Leo F. Verdonck, Robert P. Gale, Betty K Hamilton, Navneet S Majhail, and Alison W Loren
The potential of achiral sponge-derived and synthetic bromoindoles as selective cytotoxins against PANC-1 tumor cells, Nicholas Lorig-Roach, Frances Hamkins-Indik, Tyler A. Johnson, Karen Tenney, Frederick A. Valeriote, and Phillip Crews
SAPHO Syndrome Masquerading as Metastatic Breast Cancer, Devin Malik, Richa Handa, Andrew Petraszko, and Sheela Tejwani
Normolipemic Xanthomas in a Patient with Underlying Plasma Cell Dyscrasia, Devin Malik, Sukhpreet Singh, and Akshay Amaraneni
Breast cancer metastasis through the lympho-vascular system, S. David Nathanson, David Krag, Henry M. Kuerer, Lisa A. Newman, Markus Brown, Dontscho Kerjaschki, Ethel R. Pereira, and Timothy P. Padera
Utilization of the 21-Gene Recurrence Score in a Diverse Breast Cancer Patient Population: Development of a Clinicopathologic Model to Predict High-Risk Scores and Response to Neoadjuvant Chemotherapy, Ko-Un Park, Yalei Chen, Dhananjay A. Chitale, Sarah Choi, Haythem Y. Ali, S David Nathanson, Jessica Bensenhaver, Erica Proctor, Lindsay Petersen, Randa Loutfi, Alyson Simonds, Marcia Kuklinski, Thomas Doyle, Vrushali Dabak, Kim Cole, Melissa B. Davis, and Lisa A. Newman
Avelumab in metastatic urothelial carcinoma after platinum failure (JAVELIN Solid Tumor): pooled results from two expansion cohorts of an open-label, phase 1 trial, Manish R. Patel, John Ellerton, Jeffrey R. Infante, Manish Agrawal, Michael Gordon, Raid Aljumaily, Carolyn D. Britten, Luc Dirix, Keun-Wook Lee, Mathew Taylor, Patrick Schöffski, Ding Wang, Alain Ravaud, Arnold B. Gelb, Junyuan Xiong, Galit Rosen, James L. Gulley, and Andrea B. Apolo
ALK is a critical regulator of the MYC-signaling axis in ALK positive lung cancer, Amanda B. Pilling, Jihye Kim, Adriana Estrada-Bernal, Qiong Zhou, Anh T. Le, Katherine R. Singleton, Lynn E. Heasley, Aik C. Tan, James DeGregori, and Robert C. Doebele
