Scholarly journal articles authored by members of the Division of Hematology/Oncology and the Henry Ford Cancer Institute at Henry Ford Health.

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Submissions from 2021

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Renal infarction and papular-purpuric gloves and socks syndrome (PPGSS): rare extra-haematological manifestations of acute parvovirus B-19 infection, Fawzi Abu Rous, Qunfang Li, and Yue Guo

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Clinical significance of quantitative categorization of HER2 fluorescent in situ hybridization results in invasive breast cancer patients treated with HER2-targeted agents, Mohamed Alhamar, Bassam Alkamachi, Harshita Mehrotra, Jessica Sanchez, Haythem Y. Ali, Daniel Schultz, and Dhananjay A. Chitale

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p16 positive oropharyngeal small cell cancer: A case report, Nada Al Masalmeh, Geetika Kukreja, Feras Zaiem, S. Naweed Raza, Harold Kim, Misako Nagasaka, and Ammar Sukari

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A Dose-finding Study Followed by a Phase II Randomized, Placebo-controlled Trial of Chemoradiotherapy With or Without Veliparib in Stage III Non-small-cell Lung Cancer: SWOG 1206 (8811), Athanassios Argiris, Jieling Miao, Mihaela C. Cristea, Allen M. Chen, Jacob M. Sands, Roy H. Decker, Scott N. Gettinger, Megan E. Daly, Bryan A. Faller, Kathy S. Albain, Ronald H. Yanagihara, Linda L. Garland, Lauren A. Byers, Ding Wang, Marianna Koczywas, Mary W. Redman, Karen Kelly, and David R. Gandara

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P-selectin expression assay in a repeatedly serotonin-release assay-negative patient with heparin-induced thrombocytopenia, Kanika Arora, Shannon Rodgers, Yaser Alkhatib, Ifeoma Onwubiko, Anand Padmanabhan, and Zaher K. Otrock

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Acquired Resistance to KRAS (G12C) Inhibition in Cancer, Mark M. Awad, Shengwu Liu, Igor I. Rybkin, Kathryn C. Arbour, Julien Dilly, Viola W. Zhu, Melissa L. Johnson, Rebecca S. Heist, Tejas Patil, Gregory J. Riely, Joseph O. Jacobson, Xiaoping Yang, Nicole S. Persky, David E. Root, Kristen E. Lowder, Hanrong Feng, Shannon S. Zhang, Kevin M. Haigis, Yin P. Hung, Lynette M. Sholl, Brian M. Wolpin, Julie Wiese, Jason Christiansen, Jessica Lee, Alexa B. Schrock, Lee P. Lim, Kavita Garg, Mark Li, Lars D. Engstrom, Laura Waters, J. David Lawson, Peter Olson, Piro Lito, Sai-Hong I. Ou, James G. Christensen, Pasi A. Jänne, and Andrew J. Aguirre

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A Case of Chronic Eosinophilic Leukemia in a Patient With Recurrent Cough, Dyspnea, and Eosinophilia, Nino Balanchivadze, James P. Purtell, Jessica Anderson, Yue Guo, and Irina Dobrosotskaya

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NRG-HN003: Phase I and Expansion Cohort Study of Adjuvant Pembrolizumab, Cisplatin and Radiation Therapy in Pathologically High-Risk Head and Neck Cancer, Julie E. Bauman, Jonathan Harris, Ravindra Uppaluri, Min Yao, Robert L. Ferris, Josephine Chen, Richard C. Jordan, Nikhil P. Joshi, Srinivas Jujjuvaparu, Dukagjin M. Blakaj, Christina Henson, Jawad Sheqwara, Loren K. Mell, Neilayan Sen, David A. Clump, Madhur K. Garg, Emrullah Yilmaz, Pedro Torres-Saavedra, and Quynh-Thu Le

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Screening mammography mitigates breast cancer disparities through early detection of triple negative breast cancer, Solange Bayard, Genevieve Fasano, Yalei Chen, Melissa Davis, Michele Drotman, Jessica Bensenhaver, Alexander Swistel, Rache Simmons, Jennifer Marti, and Lisa Newman

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Comparative clinical outcomes for patients with advanced NSCLC harboring EGFR exon 20 insertion mutations and common EGFR mutations, Lyudmila Bazhenova, Anna Minchom, Santiago Viteri, Joshua M. Bauml, Sai-Hong Ignatius Ou, Shirish M. Gadgeel, José Manuel Trigo, Daniel Backenroth, Tracy Li, Anil Londhe, Parthiv Mahadevia, and Nicolas Girard

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Discovery of the pancreatic basal cell: a new candidate for an adult stem cell emerges, Simone Benitz and Howard C. Crawford

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Anticipating resistance to KRAS inhibition: a novel role for USP21 in macropinocytosis regulation, Howard C. Crawford

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Loss of the ciliary protein Chibby1 in mice leads to exocrine pancreatic degeneration and pancreatitis, Benjamin Cyge, Vera Voronina, Mohammed Hoque, Eunice N. Kim, Jason Hall, Jennifer M. Bailey-Lundberg, Gregory J. Pazour, Howard C. Crawford, Randall T. Moon, Feng-Qian Li, and Ken-Ichi Takemaru

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Portobelamides A and B and Caciqueamide, Cytotoxic Peptidic Natural Products from a Caldora sp. Marine Cyanobacterium, Ozlem Demirkiran, Jehad Almaliti, Tiago Leão, Gabriel Navarro, Tara Byrum, Frederick A. Valeriote, Lena Gerwick, and William H. Gerwick

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Executive Summary of the American Radium Society Appropriate Use Criteria for Radiation Treatment of Node-Negative Muscle Invasive Bladder Cancer, Tru-Khang T. Dinh, Timur Mitin, Hilary P. Bagshaw, Karen E. Hoffman, Clara Hwang, R. Jeffrey Karnes, Amar U. Kishan, Stanley L. Liauw, Shane Lloyd, Louis Potters, Timothy N. Showalter, Al V. Taira, Neha Vapiwala, Nicholas G. Zaorsky, Anthony V. D'Amico, Paul L. Nguyen, and Brian J. Davis

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Blood First Assay Screening Trial (BFAST) in Treatment-Naive Advanced or Metastatic NSCLC: Initial Results of the Phase 2 ALK-Positive Cohort, Rafal Dziadziuszko, Tony Mok, Solange Peters, Ji-Youn Han, Jorge Alatorre-Alexander, Natasha Leighl, Virote Sriuranpong, Maurice Pérol, Gilberto de Castro Junior, Ernest Nadal, Filippo de Marinis, Osvaldo Arén Frontera, Daniel S W Tan, Dae Ho Lee, Hye Ryun Kim, Mark Yan, Todd Riehl, Erica Schleifman, Sarah M. Paul, Simonetta Mocci, Rajesh Patel, Zoe June Assaf, David S. Shames, Michael S. Mathisen, and Shirish M. Gadgeel

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Long-Term Report of a Comprehensive Molecular and Genomic Analysis in NRG Oncology/RTOG 0424: A Phase II Study of Radiation and Temozolomide in High-Risk Grade II Glioma, Jessica L. Fleming, Stephanie L. Pugh, Barbara J. Fisher, Glenn J. Lesser, David R. Macdonald, Erica H. Bell, Joseph P. McElroy, Aline P. Becker, Cynthia D. Timmers, Kenneth D. Aldape, C. Leland Rogers, Thomas J. Doyle, Maria Werner-Wasik, Jean-Paul Bahary, Hsiang-Hsuan Michael Yu, David P. D'Souza, Nadia N. Laack, Penny K. Sneed, Young Kwok, Minhee Won, Minesh P. Mehta, and Arnab Chakravarti

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Patient-Reported Outcomes in the Era of Immunotherapy Trials, Shirish M. Gadgeel

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Fast progression in non-small cell lung cancer: results from the randomized phase III OAK study evaluating second-line atezolizumab versus docetaxel, David Gandara, Martin Reck, Denis Moro-Sibilot, Julien Mazieres, Shirish M. Gadgeel, Stefanie Morris, Andres Cardona, Diana Mendus, Marcus Ballinger, Achim Rittmeyer, and Solange Peters

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Safety of pemetrexed plus platinum in combination with pembrolizumab for metastatic nonsquamous non-small cell lung cancer: A post hoc analysis of KEYNOTE-189, Edward B. Garon, Joachim Aerts, Jong Seok Kim, Catherine E Muehlenbein, Patrick Peterson, Maria Teresa Rizzo, and Shirish M. Gadgeel

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The actual and ideal roles of haemophilia treatment centre social workers in the United States and the barriers to ideal roles, Margaret K. Geary, Ellen Kachalsky, and Aric Parnes

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Pembrolizumab plus dinaciclib in patients with hematologic malignancies: the phase 1b KEYNOTE-155 study, Gareth Peter Gregory, Shaji K. Kumar, Ding Wang, Daruka Mahadevan, Patricia A. Walker, Nina D. Wagner-Johnston, Carolina Escobar, Rajat Bannerji, Divava Bhutani, Julie E. Chang, Francisco J. Hernandez-Ilizaliturri, Andreas Klein, John M. Pagel, Witold Rybka, Andrew J. Yee, Anne Mohrbacher, Mo Huang, Mohammed Z. H. Farooqui, Patricia Marinello, and Hang Quach

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Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: a report from the COVID-19 and Cancer Consortium, P Grivas, A R Khaki, T M Wise-Draper, B French, C Hennessy, C-Y Hsu, Y Shyr, X Li, T K Choueiri, C A Painter, S Peters, B I Rini, M A Thompson, S Mishra, D R Rivera, J D Acoba, M Z Abidi, Z Bakouny, B Bashir, T Bekaii-Saab, S Berg, E H Bernicker, M A Bilen, P Bindal, R Bishnoi, N Bouganim, D W Bowles, A Cabal, P F Caimi, D D Chism, J Crowell, C Curran, A Desai, B Dixon, D B Doroshow, E B Durbin, A Elkrief, D Farmakiotis, A Fazio, L A Fecher, D B Flora, C R Friese, J Fu, Shirish M. Gadgeel, M D Galsky, D M Gill, M J Glover, S Goyal, P Grover, S Gulati, S Gupta, S Halabi, T R Halfdanarson, B Halmos, D J Hausrath, J E Hawley, E Hsu, M Huynh-Le, Clara Hwang, C Jani, A Jayaraj, D B Johnson, A Kasi, H Khan, V S Koshkin, N M Kuderer, D H Kwon, P E Lammers, A Li, A Loaiza-Bonilla, C A Low, M B Lustberg, G H Lyman, R R McKay, C McNair, H Menon, R A Mesa, V Mico, D Mundt, G Nagaraj, E S Nakasone, J Nakayama, A Nizam, N L Nock, C Park, J M Patel, K G Patel, P Peddi, N A Pennell, A J Piper-Vallillo, M Puc, D Ravindranathan, M E Reeves, D Y Reuben, L Rosenstein, R P Rosovsky, S M Rubinstein, M Salazar, A L Schmidt, G K Schwartz, M R Shah, S A Shah, C Shah, J A Shaya, Sunny R.K. Singh, M Smits, K E Stockerl-Goldstein, D G Stover, M Streckfuss, S Subbiah, L Tachiki, E Tadesse, A Thakkar, M D Tucker, A K Verma, D C Vinh, M Weiss, J T Wu, E Wulff-Burchfield, Z Xie, P P Yu, T Zhang, A Y Zhou, H Zhu, L Zubiri, D P Shah, J L Warner, and GdL Lopes

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Clinical outcomes of COVID-19 in patients with sickle cell disease and sickle cell trait: A critical appraisal of the literature, Wouter S. Hoogenboom, Tharun T. Alamuri, Daniel M. McMahon, Nino Balanchivadze, Vrushali Dabak, William B. Mitchell, Kerry B. Morrone, Deepa Manwani, and Tim Q. Duong

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Effect of ceritinib on the pharmacokinetics of coadministered CYP3A and 2C9 substrates: a phase I, multicenter, drug-drug interaction study in patients with ALK + advanced tumors, Felipe K. Hurtado, Filippo de Braud, Javier De Castro Carpeño, Maria Jose de Miguel Luken, Ding Wang, Jeffrey Scott, Yvonne Y. Lau, Tracey McCulloch, and Morten Mau-Sorensen

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Rapid real-world data analysis of patients with cancer, with and without COVID-19, across distinct health systems, Clara Hwang, Monika A. Izano, Michael A. Thompson, Shirish M. Gadgeel, James L. Weese, Tom Mikkelsen, Andrew Schrag, Mahder Teka, Sheetal Walters, Frank M. Wolf, Jonathan Hirsch, Donna R. Rivera, Paul G. Kluetz, Harpreet Singh, and Thomas D. Brown

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Multiethnic PDX models predict a possible immune signature associated with TNBC of African ancestry, Evelyn M. Jiagge, Peter J. Ulintz, Shukmei Wong, Sean P. McDermott, Sabrina I. Fossi, Tahra K. Suhan, Mark J. Hoenerhoff, Jessica M. Bensenhaver, Barbara Salem, Michele Dziubinski, Joseph K. Oppong, Francis Aitpillah, Kyei Ishmael, Ernest Osei-Bonsu, Ernest Adjei, Awuah Baffour, Jessica Aldrich, Ahmet Kurdoglu, Kurt Fernando, David W. Craig, Jeff M. Trent, Jun Li, Dhananjay A. Chitale, Lisa A. Newman, John D. Carpten, Max S. Wicha, and Sofia D. Merajver

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The long shadow of socioeconomic deprivation over the modern management of acute myeloid leukemia: time to unravel the challenges, M. Joseph John, Philip Kuriakose, Mark Smith, Eve Roman, and Sudhir Tauro

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Apolipoprotein E promotes immune suppression in pancreatic cancer through NF-kB-mediated production of CXCL1, Samantha B. Kemp, Eileen S. Carpenter, Nina G. Steele, Katelyn L. Donahue, Zeribe Chike Nwosu, Amanda Pacheco, Ashley Velez-Delgado, Rosa E. Menjivar, Fatima Lima, Stephanie The, Carlos E. Espinoza, Kristee Brown, Daniel Long, Costas A. Lyssiotis, Arvind Rao, Yaqing Zhang, Marina Pasca di Magliano, and Howard C. Crawford

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Myeloid Cell Mediated Immune Suppression in Pancreatic Cancer, Samantha B. Kemp, Marina Pasca di Magliano, and Howard C. Crawford

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PROMISE: a real-world clinical-genomic database to address knowledge gaps in prostate cancer, Vadim S. Koshkin, Vaibhav G. Patel, Alicia Ali, Mehmet A. Bilen, Deepak Ravindranathan, Joseph J. Park, Olesia Kellezi, Marcin Cieslik, Justin Shaya, Angelo Cabal, Landon Brown, Matthew Labriola, Laura S. Graham, Colin Pritchard, Abhishek Tripathi, Sanober Nusrat, Pedro Barata, Albert Jang, Shuang R. Chen, Rohan Garje, Luna Acharya, Clara Hwang, Amanda B. Pilling, William Oh, Tomi Jun, Divya Natesan, Chris Nguyen, Deepak Kilari, Michael Pierro, Bicky Thapa, Frank Cackowski, Alleda Mack, Elisabeth Heath, Catherine H. Marshall, Scott T. Tagawa, Susan Halabi, Michael T. Schweizer, Andrew Armstrong, Tanya Dorff, Ajjai Alva, and Rana McKay

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Association between ibrutinib treatment and hypertension, Dae Hyun Lee, Fahad Hawk, Kieun Seok, Matthew Gliksman, Josephine Emole, Isaac B. Rhea, Federico Viganego, Allan Welter-Frost, Merna Armanious, Bijal Shah, Juliio C. Chavez, Javier Pinilla-Ibarz, Matthew B. Schabath, and Michael Fradley

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The CoVID-TE risk assessment model for venous thromboembolism in hospitalized patients with cancer and COVID-19, Ang Li, Nicole M. Kuderer, Chih-Yuan Hsu, Yu Shyr, Jeremy L. Warner, Dimpy P. Shah, Vaibhav Kumar, Surbhi Shah, Amit A. Kulkarni, Julie Fu, Shuchi Gulati, Rebecca L. Zon, Monica Li, Aakash Desai, Pamela C. Egan, Ziad Bakouny, Devendra Kc, Clara Hwang, Imo J. Akpan, Rana R. McKay, Jennifer Girard, Andrew L. Schmidt, Balazs Halmos, Michael A. Thompson, Jaymin M. Patel, Nathan A. Pennell, Solange Peters, Amro Elshoury, Gilbero de Lima Lopes, Daniel G. Stover, Petros Grivas, Brian I. Rini, Corrie A. Painter, Sanjay Mishra, Jean M. Connors, Gary H. Lyman, and Rachel P. Rosovsky

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Disparities in Utilization of Autologous Stem Cell Transplantation as Consolidative Therapy for Multiple Myeloma: A Single Institution Retrospective Review, Oleksandra Lupak, Xiaoxia Han, Peter Xie, Kannan Thanikachalam, Hiba Jabbour-Aida, Shatha Farhan, and Josephine Emole

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Outcomes of in-hospital cardiopulmonary resuscitation for cardiac arrest in adult patients with metastatic solid cancers: A Nationwide Inpatient Sample database analysis from 2012 to 2014, Sindhu Malapati, Sunny R.K. Singh, Rohit Kumar, and Tarik Hadid

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What Matters Most? Predictors of Quality of Life and Life Satisfaction Among Young Breast Cancer Survivors, Kellie Martens, Gillian R. Ulrich, Krista W. Ranby, and Kristin Kilbourn

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Evolution of the Cancer Registrar in the Era of Informatics, Kelly W. Merriman, Ronda G. Broome, Giordana De Las Pozas, Lisa D. Landvogt, Ying Qi, and Judith Keating

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Tribbles 2 pseudokinase confers enzalutamide resistance in prostate cancer by promoting lineage plasticity, Jitender Monga, Indra Adrianto, Craig G. Rogers, Shirish M. Gadgeel, Dhananjay A. Chitale, Joshi J. Alumkal, Himisha Beltran, Amina Zoubeidi, and Jagadananda Ghosh

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Adenoid cystic carcinoma of the labium oris with rare metastasis to the pleural cavity, Osama Mosalem, Anas Alsara, Fawzi Abu Rous, and Borys Hrinczenko

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Impact of Oral Chemotherapy Management Program on Capecitabine Toxicity Management, Salin Nhean, Diana Kostoff, Jessica J. Yang, Vishnuprabha Vogel, and Igor I. Rybkin

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Fludarabine and Melphalan Compared with Reduced Doses of Busulfan and Fludarabine Improve Transplantation Outcomes in Older Patients with Myelodysplastic Syndromes, Betül Oran, Kwang Woo Ahn, Caitrin Fretham, Amer Beitinjaneh, Asad Bashey, Attaphol Pawarode, Baldeep Wirk, Bart L. Scott, Bipin N. Savani, Christopher Bredeson, Daniel Weisdorf, David I. Marks, David Rizzieri, Edward Copelan, Gerhard C. Hildebrandt, Gregory A. Hale, Hemant S. Murthy, Hillard M. Lazarus, Jan Cerny, Jane L. Liesveld, Jean A. Yared, Jean Yves-Cahn, Jeffrey Szer, Leo F. Verdonck, Mahmoud Aljurf, Marjolein van der Poel, Mark Litzow, Matt Kalaycio, Michael R. Grunwald, Miguel Angel Diaz, Mitchell Sabloff, Mohamed A. Kharfan-Dabaja, Navneet S. Majhail, Nosha Farhadfar, Ran Reshef, Richard F. Olsson, Robert Peter Gale, Ryotaro Nakamura, Sachiko Seo, Saurabh Chhabra, Shahrukh Hashmi, Shatha Farhan, Siddhartha Ganguly, Sunita Nathan, Taiga Nishihori, Tania Jain, Vaibhav Agrawal, Ulrike Bacher, Uday Popat, and Wael Saber

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Thrombocytapheresis for acquired von Willebrand syndrome in a patient with essential thrombocythemia and recent multivisceral transplantation, Oluwayomi Oyedeji, Jawad Sheqwara, Ifeoma Onwubiko, Ileana Lopez-Plaza, Shunji Nagai, and Zaher K. Otrock

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Androgen receptor negatively regulates mitotic checkpoint signaling to induce docetaxel resistance in castration-resistant prostate cancer, Amanda B. Pilling, Sahn-Ho Kim, and Clara Hwang

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Bone Metastases, Skeletal-Related Events, and Survival in Patients With Metastatic Non-Small Cell Lung Cancer Treated With Immune Checkpoint Inhibitors, Angel Qin, Songzhu Zhao, Abdul Miah, Lai Wei, Sandipkumar Patel, Andrew Johns, Madison Grogan, Erin M. Bertino, Kai He, Peter G. Shields, Gregory P. Kalemkerian, Shirish M. Gadgeel, Nithya Ramnath, Bryan J. Schneider, Khaled A. Hassan, Nicholas Szerlip, Zoey Chopra, Sara Journey, Jessica Waninger, Daniel Spakowicz, David P. Carbone, Carolyn J. Presley, Gregory A. Otterson, Michael D. Green, and Dwight H. Owen

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Activity and Safety of Mobocertinib (TAK-788) in Previously Treated Non-Small Cell Lung Cancer With EGFR Exon 20 Insertion Mutations From a Phase 1/2 Trial, Gregory J. Riely, Joel W. Neal, D. Ross Camidge, Alexander I. Spira, Zofia Piotrowska, Daniel B. Costa, Anne S. Tsao, Jyoti D. Patel, Shirish M. Gadgeel, Lyudmila Bazhenova, Viola W. Zhu, Howard L. West, Tarek Mekhail, Ryan D. Gentzler, Danny Nguyen, Sylvie Vincent, Steven Zhang, Jianchang Lin, Veronica Bunn, Shu Jin, Shuanglian Li, and Pasi A. Janne

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Association Between Androgen Deprivation Therapy and Mortality Among Patients With Prostate Cancer and COVID-19, Andrew L. Schmidt, Matthew D. Tucker, Ziad Bakouny, Chris Labaki, Chih-Yuan Hsu, Yu Shyr, Andrew J. Armstrong, Tomasz M. Beer, Ragneel R. Bijjula, Mehmet A. Bilen, Cindy F. Connell, Scott Joseph Dawsey, Bryan Faller, Xin Gao, Benjamin A. Gartrell, David Gill, Shuchi Gulati, Susan Halabi, Clara Hwang, Monika Joshi, Ali Raza Khaki, Harry Menon, Michael J. Morris, Matthew Puc, Karen B. Russell, Neil J. Shah, Nima Sharifi, Justin Shaya, Michael T. Schweizer, John Steinharter, Elizabeth M. Wulff-Burchfield, Wenxin Xu, Jay Zhu, Sanjay Mishra, Petros Grivas, Brian I. Rini, Jeremy Lyle Warner, Tian Zhang, Toni K. Choueiri, Shilpa Gupta, and Rana R. McKay

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Natural history study of factor IX deficiency with focus on treatment and complications (B-Natural), Amy D. Shapiro, Margaret V. Ragni, Munira Borhany, Yasmina L. Abajas, Michael D. Tarantino, Katharina Holstein, Stacy E. Croteau, Riana Liesner, Cristina Tarango, Manuela Carvalho, Catherine McGuinn, Eva Funding, Christine L. Kempton, Christoph Bidlingmaier, Alice Cohen, Johannes Oldenburg, Susan Kearney, Christine Knoll, Philip Kuriakose, Suchitra Acharya, Ulrike M. Reiss, Roshni Kulkarni, Michelle Witkop, Stefan Lethagen, Sharyne Donfield, Petra LeBeau, Erik Berntorp, and Jan Astermark

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NCDB analysis of melanoma 2004–2015: Epidemiology and outcomes by subtype, sociodemographic factors impacting clinical presentation, and real‐world survival benefit of immunotherapy approval, Sunny R.K. Singh, Sindhu J. Malapati, Rohit Kumar, Christopher Willner, and Ding Wang

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First-in-Class Anti-immunoglobulin-like Transcript 4 Myeloid-Specific Antibody MK-4830 Abrogates a PD-1 Resistance Mechanism in Patients with Advanced Solid Tumors, Lillian L. Siu, Ding Wang, John Hilton, Ravit Geva, Drew Rasco, Ruth Perets, Anson K. Abraham, Douglas C. Wilson, Julia F. Markensohn, Jared Lunceford, Leah Suttner, Shabana Siddiqi, Rachel A. Altura, and Corinne Maurice-Dror

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Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1, in Patients with Esophageal Adenocarcinoma: Results from a Phase 1 Cohort, Benjamin Tan, Adnan Khattak, Enriqueta Felip, Karen Kelly, Patricia Rich, Ding Wang, Christoph Helwig, Isabelle Dussault, Laureen S. Ojalvo, and Nicolas Isambert

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Association of Convalescent Plasma Therapy With Survival in Patients With Hematologic Cancers and COVID-19, Michael A. Thompson, Jeffrey P. Henderson, Pankil K. Shah, Samuel M. Rubinstein, Michael J. Joyner, Toni K. Choueiri, Daniel B. Flora, Elizabeth A. Griffiths, Anthony P. Gulati, Clara Hwang, Vadim S. Koshkin, Esperanza B. Papadopoulos, Elizabeth V. Robilotti, Christopher T. Su, Elizabeth M. Wulff-Burchfield, Zhuoer Xie, Peter Paul Yu, Sanjay Mishra, Jonathon W. Senefeld, Dimpy P. Shah, and Jeremy L. Warner

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Clinical Efficacy of Enzalutamide vs Bicalutamide Combined With Androgen Deprivation Therapy in Men With Metastatic Hormone-Sensitive Prostate Cancer: A Randomized Clinical Trial, Ulka N. Vaishampayan, Lance K. Heilbrun, Paul Monk, Sheela Tejwani, Guru Sonpavde, Clara Hwang, Daryn Smith, Pallavi Jasti, Kimberlee Dobson, Brenda Dickow, Elisabeth I. Heath, Louie Semaan, Michael L. Cher, Joseph A. Fontana, and Sreenivasa Chinni

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KDM6A Regulates Cell Plasticity and Pancreatic Cancer Progression by Non-Canonical Activin Pathway, Zhujun Yi, Shanqiao Wei, Lin Jin, Sivakumar Jeyarajan, Jing Yang, Yumei Gu, Hong Sun Kim, Shula Schechter, Shuang Lu, Michelle T. Paulsen, Karan Bedi, Ishwarya Venkata Narayanan, Mats Ljungman, Howard C. Crawford, Marina Pasca di Magliano, Kai Ge, Yali Dou, and Jiaqi Shi

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Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma Treated With Liposomal Irinotecan, Kenneth H. Yu, Andrew E. Hendifar, Olatunji B. Alese, Amber Draper, Maen Abdelrahim, Ethan Burns, Gazala Khan, Paul Cockrum, Rachel H. Bhak, Catherine Nguyen, Maral DerSarkissian, Mei Sheng Duh, and Nathan Bahary

Submissions from 2020

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Avelumab as second-line therapy for metastatic, platinum-treated urothelial carcinoma in the phase Ib JAVELIN Solid Tumor study: 2-year updated efficacy and safety analysis, Andrea B. Apolo, John A. Ellerton, Jeffrey R. Infante, Manish Agrawal, Michael S. Gordon, Raid Aljumaily, Theodore Gourdin, Luc Dirix, Keun-Wook Lee, Matthew H. Taylor, Patrick Schöffski, Ding Wang, Alain Ravaud, Juliane Manitz, Gregory Pennock, Mary Ruisi, James L. Gulley, and Manish R. Patel

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Heterogeneity at the invasion front of triple negative breast cancer cells, Koh Meng Aw Yong, Peter J. Ulintz, Sara Caceres, Xu Cheng, Liwei Bao, Zhifen Wu, Evelyn M. Jiagge, and Sofia D. Merajver

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Hematology/Oncology Fellowship Emergency Restructuring in Response to the COVID-19 Pandemic—Henry Ford Hospital, Michigan, Nino Balanchivadze and Vijayalakshmi Donthireddy

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Impact of COVID-19 Infection on 24 Patients with Sickle Cell Disease One Center Urban Experience, Detroit, MI, USA, Nino Balanchivadze, Adam A. Kudirka, Sally FK Askar, Khaled Almadhoun, Philip Kuriakose, Raef Fadel, and Vrushali Dabak

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American Radium Society Appropriate Use Criteria: Radiation Therapy for Limited-Stage SCLC 2020, Stephen G. Chun, Charles B. Simone, Arya Amini, Indrin J. Chetty, Jessica Donington, Martin J. Edelman, Kristin A. Higgins, Larry L. Kestin, Benjamin Movsas, George B. Rodrigues, Kenneth E. Rosenzweig, Ben J. Slotman, Igor I. Rybkin, Andrea Wolf, and Joe Y. Chang

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Synthesis, Cytotoxicity, and Genotoxicity of 10-Aza-9-oxakalkitoxin, an N,N,O-Trisubstituted Hydroxylamine Analog, or Hydroxalog, of a Marine Natural Product, Sandeep Dhanju, Kapil Upadhyaya, Christopher A. Rice, Scott D. Pegan, Joe Media, Frederick A. Valeriote, and David Crich

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Olaparib and durvalumab in patients with germline BRCA-mutated metastatic breast cancer (MEDIOLA): an open-label, multicentre, phase 1/2, basket study, Susan M. Domchek, Sophie Postel-Vinay, Seock-Ah Im, Yeon Hee Park, Jean-Pierre Delord, Antoine Italiano, Jerome Alexandre, Benoit You, Sara Bastian, Matthew G Krebs, Ding Wang, Saiama N. Waqar, Mark Lanasa, Joon Rhee, Haiyan Gao, Vidalba Rocher-Ros, Emma V. Jones, Sakshi Gulati, Anna Coenen-Stass, Iwanka Kozarewa, Zhongwu Lai, Helen K. Angell, Laura Opincar, Pia Herbolsheimer, and Bella Kaufman

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Using whole breast ultrasound tomography to improve breast cancer risk assessment: A novel risk factor based on the quantitative tissue property of sound speed, Neb Duric, Mark Sak, Shaoqi Fan, Ruth M. Pfeiffer, Peter J. Littrup, Michael S. Simon, David H. Gorski, Haythem Y. Ali, Kristen S. Purrington, Rachel F. Brem, Mark E. Sherman, and Gretchen L. Gierach

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A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry, Zhaohui Du, Niels Weinhold, Gregory C. Song, Kristin A. Rand, David J. Van Den Berg, Amie E. Hwang, Xin Sheng, Victor Hom, Sikander Ailawadhi, Ajay K. Nooka, Seema Singhal, Karen Pawlish, Edward S. Peters, Cathryn Bock, Ann Mohrbacher, Alexander Stram, Sonja I. Berndt, William J. Blot, Graham Casey, Victoria L. Stevens, Rick Kittles, Phyllis J. Goodman, W R. Diver, Anselm Hennis, Barbara Nemesure, Eric A. Klein, Benjamin A. Rybicki, Janet L. Stanford, John S. Witte, Lisa Signorello, Esther M. John, Leslie Bernstein, Antoinette M Stroup, Owen W Stephens, Maurizio Zangari, Frits Van Rhee, Andrew Olshan, Wei Zheng, Jennifer J Hu, Regina Ziegler, Sarah J Nyante, Sue Ann Ingles, Michael F Press, John David Carpten, Stephen J Chanock, Jayesh Mehta, Graham A Colditz, Jeffrey Wolf, Thomas G Martin, Michael Tomasson, Mark A Fiala, Howard Terebelo, Nalini Janakiraman, Laurence Kolonel, Kenneth C Anderson, Loic Le Marchand, Daniel Auclair, Brian C-H Chiu, Elad Ziv, Daniel Stram, Ravi Vij, Leon Bernal-Mizrachi, Gareth J Morgan, Jeffrey A Zonder, Carol Ann Huff, Sagar Lonial, Robert Z Orlowski, David V Conti, Christopher A Haiman, and Wendy Cozen

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Phase II Study of a Temozolomide-Based Chemo-radiotherapy Regimen for High Risk Low-Grade Gliomas: Long-term Results of Radiation Therapy Oncology Group (RTOG) 0424, Barbara J. Fisher, Stephanie L. Pugh, David R. Macdonald, Arnab Chakravatri, Glenn J. Lesser, Sherry Fox, C L. Rogers, Maria Werner-Wasik, Thomas Doyle, Jean-Paul Bahary, John B. Fiveash, Joseph A. Bovi, Steven P. Howard, Hsiang-Hsuan Michael Yu, David D'Souza, Nadia N. Laack, Igor J. Barani, Young Kwok, Daniel R. Wahl, Jon F. Strasser, Minhee Won, and Minesh P. Mehta

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Electrocardiographic Changes Associated With Ibrutinib Exposure, Michael G. Fradley, Allan Welter-Frost, Matthew Gliksman, Josephine Emole, Federico Viganego, Dae Hyun Lee, Bijal Shah, Julio C. Chavez, Javier Pinilla-Ibarz, and Matthew B. Schabath

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Neratinib plus Cetuximab in Quadruple WT (KRAS, NRAS, BRAF, PIK3CA) Metastatic Colorectal Cancer Resistant to Cetuximab or Panitumumab: NSABP FC-7, A Phase Ib Study, Samuel A. Jacobs, James J. Lee, Thomas J. George, James L. Wade, Philip J. Stella, Ding Wang, Ashwin Sama, Fanny Piette, Katherine L Pogue-Geile, Rim S. Kim, Patrick G. Gavin, Corey Lipchik, Huichen Feng, Ying Wang, Melanie Finnigan, Brian Kiesel, Jan H. Beumer, Norman Wolmark, Peter C. Lucas, Carmen J. Allegra, and Ashok Srinivasan

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Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8, Tyler A. Johnson, Joseph D. Morris, David A. Coppage, Colon V. Cook, Lauren N. Persi, Marcos A. Ogarrio, Taylor C. Garcia, Nicole L. McIntosh, Erin P. McCauley, Joe Media, Mani Maheshwari, Frederick A. Valeriote, Jiajiu Shaw, and Phillip Crews

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Is the HERV-K HML-2 Xq2133, an endogenous retrovirus mutated by gene conversion of chromosome X in a subset of African populations, associated with human breast cancer?, Mark H. Kaplan, Rafael Contreras-Galindo, Evelyn M. Jiagge, Sofia D. Merajver, Lisa Newman, Galya Bigman, Michael H. Dosik, Ganesh S. Palapattu, Javed Siddiqui, Arul M. Chinnaiyan, Sally Adebamowo, and Clement Adebamowo

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BRAINSTORM: A Multi-Institutional Phase I/II Study of RRx-001 in Combination with Whole Brain Radiation Therapy for Patients with Brain Metastases, Michelle M Kim, Hemant A Parmar, Matthew Schipper, Theresa Devasia, Madhava P Aryal, Santosh Kesari, Steven O'Day, Aki Morikawa, Daniel E Spratt, Larry Junck, Aaron Mammoser, James A Hayman, Theodore S Lawrence, Christina I Tsien, Robert Aiken, Sharad Goyal, Nacer Abrouk, Malcolm Trimble, Yue Cao, and Christopher D. Lao

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Incidence and outcomes of heparin-induced thrombocytopenia in solid malignancy: an analysis of the National Inpatient Sample Database, Rohit Kumar, Shruti Bhandari, Sukhpreet RK Singh, Sindhu Malapati, and Kamila I. Cisak

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Poroid Hidradenoma; a Benign Lesion Masking as Malignant Breast Tumor, Hassan Liaqat, Mohammad Ammad Ud Din, and Devin Malik

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Real-world effectiveness of the pegfilgrastim on-body injector in preventing severe neutropenia, Lucas G. Maahs, Amy Tang, Zaid Al-Saheli, Brigid Jacob, Rishika Polasani, and Clara Hwang

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Atezolizumab Versus Docetaxel in Pretreated Patients With NSCLC: Final Results From the Randomized Phase 2 POPLAR and Phase 3 OAK Clinical Trials, Julien Mazieres, Achim Rittmeyer, Shirish M. Gadgeel, Toyoaki Hida, David R. Gandara, Diego L. Cortinovis, Fabrice Barlesi, Wei Yu, Christina Matheny, Marcus Ballinger, and Keunchil Park

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Outcomes According to ALK Status Determined by Central Immunohistochemistry or Fluorescence In Situ Hybridization in Patients With ALK-Positive NSCLC Enrolled in the Phase 3 ALEX Study, Tony Mok, Solange Peters, D. Ross Camidge, Johannes Noé, Shirish M. Gadgeel, Sai-Hong I. Ou, Dong-Wan Kim, Krzysztof Konopa, Emanuela Pozzi, Ting Liu, Isabell R. Loftin, Crystal Williams, and Alice T. Shaw

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Bilateral breast masses as a presentation for T-cell acute lymphoblastic leukaemia, Osama Mosalem, Fawzi Abu Rous, Ahmed Elshafie, and Daniel Isaac

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Pulmonary embolism as the primary presentation of IgA vasculitis, Osama Mosalem, Nora Hernandez Garcilazo, Yehia Saleh, and Fawzi Abu Rous

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A user's guide to lorlatinib, Misako Nagasaka, Yubin Ge, Ammar Sukari, Geetika Kukreja, and Sai-Hong Ignatius Ou

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Predictors of response and outcome of patients with acquired haemophilia A, Ifeoma Onwubiko, Gary Kasperek, Rosarina A. Laforest, Samuel G. Philip, Philip Kuriakose, and Zaher K. Otrock

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Cold agglutinin disease and autoimmune hemolytic anemia with pulmonary embolism as a presentation of COVID-19 infection, Neha R. Patil, Erica S. Herc, and Marian R. Girgis

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Exceptional Response to A Single Cycle of Immunotherapy in a Lynch Syndrome Patient with Metastatic Pancreatic Adenocarcinoma, Neha R. Patil and Gazala N. Khan

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Primary Pleural Extranodal Marginal Zone Lymphoma Presenting as Bilateral Chylothorax, Thushara Paul, Dhiraj K. Yadav, Mohamed Alhamar, and Vrushali Dabak

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Molecular therapeutic targets in non-small cell lung cancer, Kamya Sankar, Shirish M. Gadgeel, and Angel Qin

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A Versatile Chemoenzymatic Synthesis for the Discovery of Potent Cryptophycin Analogs, Jennifer J Schmidt, Yogan Khatri, Scott I Brody, Catherine Zhu, Halina Pietraszkiewicz, Frederick A. Valeriote, and David H. Sherman

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Toxicity in combination immune checkpoint inhibitor and radiation therapy: a systematic review and meta-analysis, Congzhou M Sha, Eric J. Lehrer, Clara Hwang, Daniel M. Trifiletti, Heath B. Mackley, Joseph J. Drabick, and Nicholas G. Zaorsky

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Desperate times, desperate measures: successful use of chemotherapy in treatment of haemophagocytic lymphohistiocytosis (HLH) due to disseminated histoplasmosis, Sunny RK Singh, Kannan Thanikachalam, and Vijayalakshmi Donthireddy

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COVID-19 and Cancer: Lessons Learnt from a Michigan Hotspot, Sunny RK Singh, Kannan Thanikachalam, Hiba Jabbour Aida, Laila M. Poisson, and Gazala Khan

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Pseudo-Thrombocytosis Caused by Extreme Microcytosis in a Patient with Alpha Thalassemia Trait, Alexander A. Slota, Devin Malik, and Diane Hall

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Optimal Donor for African Americans with Hematologic Malignancy: HLA-Haploidentical Relative or Umbilical Cord Blood Transplant, Scott R. Solomon, Andrew St. Martin, Mei-Jie Zhang, Karen Ballen, Asad Bashey, Minoo Battiwalla, Lee Ann Baxter-Lowe, Claudio Brunstein, Saurabh Chhabra, Miguel Perez, Ephraim J. Fuchs, Siddhartha Ganguly, Nancy Hardy, Peiman Hematti, Joseph McGuirk, Edward Peres, Olle Ringden, David Rizzieri, Rizwan Romee, Melhem Solh, David Szwajcer, Marjolein van der Poel, Edmund Waller, Basem M. William, and Mary Eapen

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Brief Report: Randomized Phase 2 Studies of Checkpoint Inhibitors Alone or in Combination with Pegilodecakin in Patients with Metastatic Non-Small-Cell Lung Cancer (CYPRESS-1 and CYPRESS-2), David Spigel, Robert Jotte, John Nemunaitis, Merrill Shum, Jeffrey Schneider, Jerome Goldschmidt, Jennifer Eisenstein, David Berz, Lasika Seneviratne, Matei Socoteanu, Viralkumar Bhanderi, Kartik Konduri, Meng Xia, Hong Wang, Rebecca R Hozak, Ivelina Gueorguieva, David Ferry, Leena Gandhi, Bo H Chao, and Igor Rybkin

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The role of immune checkpoint inhibitors in anaplastic thyroid cancer (Case Series), Ammar Sukari, Geetika Kukreja, Misako Nagasaka, Mohammad K. Shukairy, George Yoo, Ho-Sheng Lin, Jeffrey Hotaling, and Harold Kim

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Disparities in the Uptake of Telemedicine During the COVID-19 Surge in a Multidisciplinary Head and Neck Cancer Population by Patient Demographic Characteristics and Socioeconomic Status, Samantha Tam, Vivian Wu, Amy M. Williams, Marian R. Girgis, Jawad Z. Sheqwara, Farzan Siddiqui, and Steven S. Chang

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Neoadjuvant Phase II Trial of Chemoradiotherapy in Patients With Resectable and Borderline Resectable Pancreatic Cancer, Kannan Thanikachalam, Vijay Damarla, Trevor Seixas, Irina Dobrosotskaya, Ira Wollner, David Kwon, Kenneth Winters, Mohammad Raoufi, Jia Li, Farzan Siddiqui, and Gazala Khan

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Efficacy and safety of first-line avelumab in patients with advanced non-small cell lung cancer: results from a phase Ib cohort of the JAVELIN Solid Tumor study, Claire F. Verschraegen, Guy Jerusalem, Edward F. McClay, Nicholas Iannotti, Charles H. Redfern, Jaafar Bennouna, Franklin L. Chen, Karen Kelly, Janice Mehnert, John C. Morris, Matthew Taylor, David Spigel, Ding Wang, Hans Juergen Grote, Dongli Zhou, Neru Munshi, Marcis Bajars, and James L. Gulley

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Phase 1 study of mTORC1/2 inhibitor sapanisertib (TAK-228) in advanced solid tumours, with an expansion phase in renal, endometrial or bladder cancer, Martin H. Voss, Michael S. Gordon, Monica Mita, Brian Rini, Vicky Makker, Teresa Macarulla, David C. Smith, Andrés Cervantes, Igor Puzanov, Roberto Pili, Ding Wang, Shadia Jalal, Shubham Pant, Manish R. Patel, Rachel L. Neuwirth, Aaron Enke, Yaping Shou, Farhad Sedarati, Douglas V. Faller, and Howard A. Burris

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Variability in Cytogenetic Testing for Multiple Myeloma: A Comprehensive Analysis From Across the United States, Yang Yu, Niquelle Brown Wade, Amie E. Hwang, Ajay K. Nooka, Mark A. Fiala, Ann Mohrbacher, Edward S. Peters, Karen Pawlish, Cathryn Bock, David J. Van Den Berg, Kristin A. Rand, Daniel Stram, David V. Conti, Daniel Auclair, Graham A. Colditz, Jayesh Mehta, Christopher A. Haiman, Howard Terebelo, Nalini Janakiraman, Seema Singhal, Brian Chiu, Ravi Vij, Leon Bernal-Mizrachi, Jeffrey A. Zonder, Carol A. Huff, Sagar Lonial, Robert Z. Orlowski, Wendy Cozen, and Sikander Ailawadhi

Submissions from 2019

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Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents, Jehad Almaliti, Bailey Miller, Halina Pietraszkiewicz, Evgenia Glukhov, C B. Naman, Toni Kline, Jeffrey Hanson, Xiaofan Li, Sihong Zhou, Frederick A. Valeriote, and William H. Gerwick

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Rates of deep molecular response by digital and conventional PCR with frontline nilotinib in newly diagnosed chronic myeloid leukemia: a landmark analysis, Jesus G. Berdeja, Michael C. Heinrich, Shaker R. Dakhil, Stuart L. Goldberg, Martha Wadleigh, Philip Kuriakose, Jorge Cortes, Jerald Radich, Bret Helton, David Rizzieri, Carole Paley, Ilva Dautaj, and Michael J. Mauro

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Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp, Eduardo JE Caro-Diaz, Frederick A. Valeriote, and William H. Gerwick

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A phase Ib study of utomilumab (PF-05082566) in combination with mogamulizumab in patients with advanced solid tumors, Ezra EW Cohen, Michael J. Pishvaian, Dale R. Shepard, Ding Wang, Jared Weiss, Melissa L. Johnson, Christine H. Chung, Ying Chen, Bo Huang, Craig B. Davis, Francesca Toffalorio, Aron Thall, and Steven F. Powell

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The effects of lapatinib on cardiac repolarization: results from a placebo controlled, single sequence, crossover study in patients with advanced solid tumors, Shodeinde A. Coker, Herbert I. Hurwitz, Sunil Sharma, Ding Wang, Pierre Jordaan, Juan P. Zarate, and Lionel D. Lewis