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Submissions from 2019

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cGMP Induces Degradation of NKCC2 in the Thick Ascending Limb via the Ubiquitin-Proteasomal System., Gustavo R Ares

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Fructose acutely stimulates NKCC2 activity in rat thick ascending limbs by increasing surface NKCC2 expression., Gustavo R Ares, Kamal M Kassem, and Pablo A Ortiz

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ATP release into ADPKD cysts via pannexin-1/P2X7 channels decreases ENaC activity., Sergey N Arkhipov and Tengis S. Pavlov

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Gout, Hyperuricemia, and Crystal-Associated Disease Network Consensus Statement Regarding Labels and Definitions for Disease Elements in Gout., David Bursill, William J Taylor, Robert Terkeltaub, Masanari Kuwabara, Tony R Merriman, Rebecca Grainger, Carlos Pineda, Worawit Louthrenoo, N Lawrence Edwards, Mariano Andrés, Ana Beatriz Vargas-Santos, Edward Roddy, Tristan Pascart, Ching-Tsai Lin, Fernando Perez-Ruiz, Sara K Tedeschi, Seoyoung C Kim, Leslie R Harrold, Geraldine McCarthy, Nitin Kumar, Peter T Chapman, Anne-Kathrin Tausche, Janitzia Vazquez-Mellado, Marwin Gutierrez, Geraldo da Rocha Castelar-Pinheiro, Pascal Richette, Eliseo Pascual, Mark C Fisher, Ruben Burgos-Vargas, Philip C Robinson, Jasvinder A Singh, Tim L Jansen, Kenneth G Saag, Ole Slot, Tillmann Uhlig, Daniel H Solomon, Robert T Keenan, Carlo Alberto Scire, Edyta Biernat-Kaluza, Mats Dehlin, George Nuki, Naomi Schlesinger, Matthijs Janssen, Lisa K Stamp, Francisca Sivera, Anthony M Reginato, Lennart Jacobsson, Frédéric Lioté, Hang-Korng Ea, Ann Rosenthal, Thomas Bardin, Hyon K Choi, Michael S Hershfield, Christine Czegley, Sung Jae Choi, and Nicola Dalbeth

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Urinary concentrating defect in mice lacking Epac1 or Epac2., Alena Cherezova, Viktor Tomilin, Vadym Buncha, Oleg Zaika, Pablo A Ortiz, Fang Mei, Xiaodong Cheng, Mykola Mamenko, and Oleh Pochynyuk

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Urinary concentrating defect in mice lacking Epac1 or Epac2., Alena Cherezova, Viktor Tomilin, Vadym Buncha, Oleg Zaika, Pablo A Ortiz, Fang Mei, Xiaodong Cheng, Mykola Mamenko, and Oleh Pochynyuk

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Thymosinβ4-Ac-SDKP pathway: Any relevance for the cardiovascular system?, Kamal M Kassem, Sonal Vaid, Hongmei Peng, Sarah Sarkar, and Nour-Eddine Rhaleb

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Increased ENaC activity during kidney preservation in Wisconsin solution., Sherif Khedr, Oleg Palygin, Tengis S. Pavlov, Gregory Blass, Vladislav Levchenko, Ammar Alsheikh, Michael W Brands, Ashraf El-Meanawy, and Alexander Staruschenko

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AC-SDKP treatment protects heart against excessive myocardial injury and heart failure in mice, Hongmei Peng, Jiang Xu, Xiao-Ping Yang, Kamal M Kassem, Imane A. Rhaleb, Edward L. Peterson, and Nour-Eddine Rhaleb

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Tubule-vascular feedback in renal autoregulation., Cesar A Romero and Oscar A. Carretero

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Renal release of N-acetyl-seryl-aspartyl-lysyl-proline is part of an antifibrotic peptidergic system in the kidney., Cesar A Romero, Nitin Kumar, Pablo Nakagawa, Morel E Worou, Tang-Dong Liao, Edward L Peterson, and Oscar A Carretero

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Renal release of N-acetyl-seryl-aspartyl-lysyl-proline is part of an antifibrotic peptidergic system in the kidney., Cesar A Romero, Nitin Kumar, Pablo Nakagawa, Morel E Worou, Tang-Dong Liao, Edward L Peterson, and Oscar A Carretero

Submissions from 2018

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β, Pei-Yin Ho, Hui Li, Tengis S. Pavlov, Roland D Tuerk, Diego Tabares, René Brunisholz, Dietbert Neumann, Alexander Staruschenko, and Kenneth R Hallows

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A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease., Daria V Ilatovskaya, Gregory Blass, Oleg Palygin, Vladislav Levchenko, Tengis S. Pavlov, Michael N Grzybowski, Kristen Winsor, Leonid S Shuyskiy, Aron M Geurts, Allen W Cowley, Lutz Birnbaumer, and Alexander Staruschenko

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Role of Alström syndrome 1 in the regulation of blood pressure and renal function., Ankita Bachhawat Jaykumar, Paulo S Caceres, Keyona N King-Medina, Tang-Dong Liao, Indrani Datta, Dipak Maskey, Jürgen K Naggert, Mariela Mendez, William H Beierwaltes, and Pablo A Ortiz

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Single-molecule labeling for studying trafficking of renal transporters., Ankita Bachhawat Jaykumar, Paulo S Caceres, and Pablo A Ortiz

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Small molecule disruption of G protein βγ subunit signaling reprograms human macrophage phenotype and prevents autoimmune myocarditis in rats., Vengadeshprabhu Karuppagounder, Anamika Bajpai, Shu Meng, Somasundaram Arumugam, Remya Sreedhar, Vijayasree V Giridharan, Ashrith Guha, Arvind Bhimaraj, Keith A Youker, Suresh S Palaniyandi, Harry Karmouty-Quintana, Fadia Kamal, Kara L Spiller, Kenichi Watanabe, and Rajarajan A Thandavarayan

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Thymosin β4 Deficiency Exacerbates Renal and Cardiac Injury in Angiotensin-II-Induced Hypertension., Nitin Kumar, Tang-Dong Liao, Cesar A Romero, Mani Maheshwari, Edward L Peterson, and Oscar A Carretero

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Renal Protective Effects of N-Acetyl-Seryl-Aspartyl-Lysyl-Proline (Ac-SDKP) in Obese Rats on a High-Salt Diet., Mani Maheshwari, Cesar A Romero, Sumit R Monu, Nitin Kumar, Tang-Dong Liao, Edward L Peterson, and Oscar A Carretero

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Role of connecting tubule glomerular feedback in obesity related renal damage., Sumit R Monu, Mani Maheshwari, Edward L Peterson, and Oscar A Carretero

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Connecting tubule glomerular feedback mediates tubuloglomerular feedback resetting after unilateral nephrectomy., Sumit R Monu, Yilin Ren, J X Masjoan-Juncos, Kristopher Kutskill, Hong Wang, Nitin Kumar, Edward L Peterson, and Oscar A Carretero

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Ac-SDKP decreases mortality and cardiac rupture after acute myocardial infarction., Pablo Nakagawa, Cesar A Romero, Xu Jiang, Martin D'Ambrosio, Ginette Bordcoch, Edward L Peterson, Pamela Harding, Xiao-Ping Yang, and Oscar A Carretero

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Ac-SDKP decreases mortality and cardiac rupture after acute myocardial infarction., Pablo Nakagawa, Cesar A Romero, Xu Jiang, Martin D'Ambrosio, Ginette Bordcoch, Edward L Peterson, Pamela Harding, Xiao-Ping Yang, and Oscar A Carretero

Characterization of purinergic receptor expression in ARPKD cystic epithelia., Oleg Palygin, Daria V Ilatovskaya, Vladislav Levchenko, Christine A Klemens, Lashodya Dissanayake, Anna Marie Williams, Tengis S. Pavlov, and Alexander Staruschenko

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Precision medicine approach: Empagliflozin for diabetic cardiomyopathy in mice with aldehyde dehydrogenase (ALDH) 2 * 2 mutation, a specific genetic mutation in millions of East Asians., Guodong Pan, Mandar Deshpande, Haiyan Pang, and Suresh S Palaniyandi

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Type-2 diabetic aldehyde dehydrogenase 2 mutant mice (ALDH 2*2) exhibiting heart failure with preserved ejection fraction phenotype can be determined by exercise stress echocardiography., Guodong Pan, Srikar Munukutla, Ananya Kar, Joseph D Gardinier, Rajarajan A Thandavarayan, and Suresh S Palaniyandi

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Noninvasive measurement of renal blood flow by magnetic resonance imaging in rats., Cesar A Romero, Glauber Cabral, Robert A Knight, Guangliang Ding, Edward L Peterson, and Oscar A Carretero

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Free radical scavenging reverses fructose-induced salt-sensitive hypertension., Zachary P Zenner, Kevin L Gordish, and William H Beierwaltes

Submissions from 2017

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MAS1 Receptor Trafficking Involves ERK1/2 Activation Through a β-Arrestin2-Dependent Pathway., Flavia M Cerniello, Oscar A Carretero, Nadia A Longo Carbajosa, Bruno D Cerrato, Robson A Santos, Hernán E Grecco, and Mariela M Gironacci

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MiR-126 Affects Brain-Heart Interaction after Cerebral Ischemic Stroke., Jieli Chen, Chengcheng Cui, Xiao-Ping Yang, Jiang Xu, Poornima Venkat, Alex Zacharek, Peng Yu, and Michael Chopp

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The senescence accelerated mouse prone 8 (SAMP8): A novel murine model for cardiac aging., Vengadeshprabhu Karuppagounder, Somasundaram Arumugam, Sahana Suresh Babu, Suresh S Palaniyandi, Kenichi Watanabe, John P Cooke, and Rajarajan A Thandavarayan

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Tiny molecule, big power: Multi-target approach for curcumin in diabetic cardiomyopathy., Vengadeshprabhu Karuppagounder, Somasundaram Arumugam, Vijayasree V Giridharan, Remya Sreedhar, Rajendran J C Bose, Jyothi Vanama, Suresh S Palaniyandi, Tetsuya Konishi, Kenichi Watanabe, and Rajarajan A Thandavarayan

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Lack of Effects of Metformin and AICAR Chronic Infusion on the Development of Hypertension in Dahl Salt-Sensitive Rats., Tengis S. Pavlov, Vladislav Levchenko, Daria V Ilatovskaya, Hui Li, Oleg Palygin, Nuria M Pastor-Soler, Kenneth R Hallows, and Alexander Staruschenko

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Effect of salt intake on afferent arteriolar dilatation: role of connecting tubule glomerular feedback (CTGF)., Hong Wang, Cesar A Romero, J X Masjoan Juncos, Sumit R Monu, Edward L Peterson, and Oscar A Carretero

Submissions from 2016

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Heteromerization Between the Bradykinin B2 Receptor and the Angiotensin-(1-7) Mas Receptor: Functional Consequences., Bruno D Cerrato, Oscar A Carretero, Brana Janic, Hernán E Grecco, and Mariela M Gironacci

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Increased 4-hydroxy-2-nonenal-induced proteasome dysfunction is correlated with cardiac damage in streptozotocin-injected rats with isoproterenol infusion., Mandar Deshpande, Vishal R Mali, Guodong Pan, Jiang Xu, Xiao-Ping Yang, Rajarajan A Thandavarayan, and Suresh S Palaniyandi

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Cardiac-deleterious role of galectin-3 in chronic angiotensin II-induced hypertension., Germán E González, Nour-Eddine Rhaleb, Martin A D'Ambrosio, Pablo Nakagawa, Tang-Dong Liao, Edward L Peterson, Pablo Leung, Xiangguo Dai, Brana Janic, Yun-He Liu, Xiao-Ping Yang, and Oscar A Carretero

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Angiotensin II stimulates superoxide production by nitric oxide synthase in thick ascending limbs., Agustin Gonzalez-Vicente, Jagannath H Saikumar, Katherine J Massey, Nancy J Hong, Fernando P Dominici, Oscar A Carretero, and Jeffrey L Garvin

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Prostaglandin E2 Reduces Cardiac Contractility via EP3 Receptor., Xiaosong Gu, Jiang Xu, Liping Zhu, Timothy Bryson, Xiao-Ping Yang, Edward L Peterson, and Pamela Harding

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Real-time monitoring of NKCC2 endocytosis by total internal reflection fluorescence (TIRF) microscopy., Ankita Bachhawat Jaykumar, Paulo S Caceres, Ibrahim M Sablaban, Bakhos A Tannous, and Pablo A Ortiz

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Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice., Vengadeshprabhu Karuppagounder, Vijayasree V Giridharan, Somasundaram Arumugam, Remya Sreedhar, Suresh S Palaniyandi, Prasanna Krishnamurthy, Joao Quevedo, Kenichi Watanabe, Tetsuya Konishi, and Rajarajan A Thandavarayan

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Residues in the Distal Heme Pocket of Arabidopsis Non-Symbiotic Hemoglobins: Implication for Nitrite Reductase Activity., Nitin Kumar, Alessandra Astegno, Jian Chen, Alejandro Giorgetti, and Paola Dominici

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The anti-inflammatory peptide Ac-SDKP is released from thymosin-β4 by renal meprin-α and prolyl oligopeptidase., Nitin Kumar, Pablo Nakagawa, Brana Janic, Cesar A Romero, Morel E Worou, Sumit R Monu, Edward L Peterson, Jiajiu Shaw, Frederick A Valeriote, Elimelda M Ongeri, Jean-Marie V Niyitegeka, Nour-Eddine Rhaleb, and Oscar A Carretero

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Impaired ALDH2 activity decreases the mitochondrial respiration in H9C2 cardiomyocytes., Vishal R Mali, Mandar Deshpande, Guodong Pan, Rajarajan A Thandavarayan, and Suresh S Palaniyandi

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Cardiac Mitochondrial Respiratory Dysfunction and Tissue Damage in Chronic Hyperglycemia Correlate with Reduced Aldehyde Dehydrogenase-2 Activity., Vishal R Mali, Guodong Pan, Mandar Deshpande, Rajarajan A Thandavarayan, Jiang Xu, Xiao-Ping Yang, and Suresh S Palaniyandi

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Alcohol Toxicity in Diabetes and Its Complications: A Double Trouble?, Srikar Munukutla, Guodong Pan, Mandar Deshpande, Rajarajan A Thandavarayan, Prasanna Krishnamurthy, and Suresh S Palaniyandi

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K+-Mediated Regulation of Distal Convoluted Tubule Na/Cl Cotransporter Phosphorylation During Angiotensin II-Induced Hypertension., Pablo A Ortiz

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ALDH2 Inhibition Potentiates High Glucose Stress-Induced Injury in Cultured Cardiomyocytes., Guodong Pan, Mandar Deshpande, Rajarajan A Thandavarayan, and Suresh S Palaniyandi

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Angiotensin II-mediated hypertension impairs nitric oxide-induced NKCC2 inhibition in thick ascending limbs., Vanesa D Ramseyer, Pablo A Ortiz, Oscar A Carretero, and Jeffrey L Garvin

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Mechanisms of connecting tubule glomerular feedback enhancement by aldosterone., Yilin Ren, Brana Janic, Kristopher Kutskill, Edward L Peterson, and Oscar A Carretero

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Role of MAPK-mediated endoplasmic reticulum stress signaling in the heart during aging in senescence-accelerated prone mice., Remya Sreedhar, Vijayasree V Giridharan, Somasundaram Arumugam, Vengadeshprabhu Karuppagounder, Suresh S Palaniyandi, Prasanna Krishnamurthy, Joao Quevedo, Kenichi Watanabe, Tetsuya Konishi, and Rajarajan A Thandavarayan

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High salt diet and caffeine: food for thought., Alexander Staruschenko, Daria V Ilatovskaya, and Tengis S. Pavlov

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Ac-SDKP suppresses TNF-α-induced ICAM-1 expression in endothelial cells via inhibition of IκB kinase and NF-κB activation., Liping Zhu, Xiao-Ping Yang, Brana Janic, Nour-Eddine Rhaleb, Pamela Harding, Pablo Nakagawa, Edward L Peterson, and Oscar A Carretero

Submissions from 2015

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Direct renal effects of a fructose-enriched diet: interaction with high salt intake., Gustavo R Ares and Pablo A Ortiz

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Concentration-independent MRI of pH with a dendrimer-based pH-responsive nanoprobe., Mohammed P I Bhuiyan, Madhava P Aryal, Brana Janic, Kishor Karki, Nadimpalli R S Varma, James R. Ewing, Ali S Arbab, and Meser M Ali

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Sca-1+ cells from fetal heart with high aldehyde dehydrogenase activity exhibit enhanced gene expression for self-renewal, proliferation, and survival., Devaveena Dey, Guodong Pan, Nadimpalli Ravi S Varma, and Suresh S Palaniyandi

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Inverse Correlation Between Plasma Adropin and ET-1 Levels in Essential Hypertension: A Cross-Sectional Study., Xiaosong Gu, Hui Li, Xinyi Zhu, Haibo Gu, Jianchang Chen, Luchen Wang, Pamela Harding, and Weiting Xu

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N-Acetyl-Seryl-Aspartyl-Lysyl-Proline: mechanisms of renal protection in mouse model of systemic lupus erythematosus., Tang-Dong Liao, Pablo Nakagawa, Brana Janic, Martin D'Ambrosio, Morel E Worou, Edward L Peterson, Nour-Eddine Rhaleb, Xiao-Ping Yang, and Oscar A Carretero

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Profibrotic Role for Interleukin-4 in Cardiac Remodeling and Dysfunction., H Peng, Zeyd Sarwar, Xiao-Ping Yang, Edward L Peterson, Jiang Xu, Brana Janic, Nadia Rhaleb, Oscar A Carretero, and Nour-Eddine Rhaleb

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Renal protective effect of N-acetyl-seryl-aspartyl-lysyl-proline in dahl salt-sensitive rats., Morel E Worou, Tang-Dong Liao, Martin D'Ambrosio, Pablo Nakagawa, Brana Janic, Edward L Peterson, Nour-Eddine Rhaleb, and Oscar A Carretero

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Activation of angiotensin II type 2 receptor suppresses TNF-α-induced ICAM-1 via NF-кB: possible role of ACE2., Liping Zhu, Oscar A Carretero, Jiang Xu, Pamela Harding, Nithya Ramadurai, Xiaosong Gu, Edward L Peterson, and Xiao-Ping Yang