Scholarly journal articles authored by members of the Department of Neurosurgery at Henry Ford Health.

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Submissions from 2025

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Establishment of a patient-derived 3D in vitro meningioma model in xeno-free hydrogel for clinical applications, Mikkel Schou Andersen, Aaraby Yoheswaran Nielsen, Martin Wirenfeldt, Jeanette Krogh Petersen, Morten Winkler Møller, Christopher L. Powell, Ana V. Castro, Grayson A. Herrgott, Tiit Mathiesen, Charlotte Aaberg Poulsen, Birgitte Brinkmann Olsen, Henning Bünsow Boldt, Christian Bonde Pedersen, Bo Halle, and Frantz Rom Poulsen

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Establishing the content validity of Patient-Reported Outcome measures used in neuro-oncology based on the WHO ICF framework: part of the RANO-PRO initiative, Ogechukwu A Asogwa, Linda Dirven, Tobias Walbert, Terri S Armstrong, David Arons, Martin J van den Bent, Jaishri Blakeley, Marijke B Coomans, Paul D Brown, Helen Bulbeck, Susan M Chang, Corneel Coens, Mark R Gilbert, Robin Grant, Rakesh Jalali, Johan A F Koekkoek, Pankaj Kumar Panda, Danielle Leach, Heather Leeper, Tito Mendoza, Lakshmi Nayak, Kathy Oliver, Jaap C Reijneveld, Emilie Le Rhun, Larry Rubinstein, Jennie W Taylor, Michael Weller, Patrick Y Wen, and Martin J B Taphoorn

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Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment, Artem D. Berezovsky, Oluwademilade Nuga, Indrani Datta, Kimberly Bergman, Thais S. Sabedot, Katherine Gurdziel, Susan M. Irtenkauf, Laura A. Hasselbach, Yuling Meng, Claudius Mueller, Emanuel F Petricoin, Stephen L. Brown, Neeraja Purandare, Sidhesh Aras, Tom Mikkelsen, Laila M. Poisson, Houtan Noushmehr, Douglas Ruden, and Ana C. de Carvalho

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Multicenter study of association between socioeconomic status and treatment of ruptured cerebral aneurysms compared to unruptured cerebral aneurysms: insights from 4,517 patients using the area deprivation index, Samhita Bheemireddy, Avi A Gajjar, Mofetoluwa Abe, Amanda Custozzo, Sonia Lipp, Andrew Ringer, Muhammed Amir Essibayi, David Altschul, Oded Goren, Jeffrey Oliver, Jared C. Reese, Pouya Entezami, Imran Chaudry, Shawn Manos, Aquilla Scott Turk, Elena Sagues, Andres Gudino, Edgar A Samaniego, Anna Luisa Kühn, Jasmeet Singh, Ajit S Puri, Joanna Mary Roy, Kareem ElNaamani, M Reid Gooch, Vinay Jaikumar, Adnan H Siddiqui, Alan S Boulos, John C Dalfino, and Alexandra R Paul

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Reporting standards in randomized controlled trials involving neuro-oncology caregivers: A systematic review report from the RANO-Cares working group, Florien W Boele, Caroline Hertler, Paula Sherwood, David Cachia, Linda Dirven, Jacob S Young, Tobias Walbert, Macy Stockdill, Eduardo Rodriguez Almaraz, and Karin Piil

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Ipsilateral Nasoseptal Flaps in a Transpterygoid Approach: Technical Pearls and Reconstruction Outcomes, Michael T Chang, David Grimm, Karam Asmaro, Michael Yong, Christopher Low, Christine K Lee, Jayakar V Nayak, Peter H Hwang, Juan C Fernandez-Miranda, and Zara M Patel

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A contemporary, multiinstitutional analysis of transcription factor lineage in pituitary adenomas: comparative study of neuroimaging, histopathology, and clinical outcomes, Stephanie K Cheok, Jacob Ruzevick, Robert G Briggs, David J Cote, Ishan Shah, David Gomez, Ilaria Bove, Jeffrey J Feng, Dhiraj J Pangal, Ben A Strickland, Mark Shiroishi, Yana Zavros, Kyle M Hurth, Anna Mathew, Norman E Garrett, Andrew S Little, Edward R Laws, Ana V. Castro, Craig M Horbinski, John D Carmichael, and Gabriel Zada

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Illness understanding and religiousness in patients with recurrent glioblastoma, John T Fortunato, Leah E Walsh, Laura C Polacek, Anne S Reiner, Tobias Walbert, Alissa A Thomas, Justin Buthorn, Allison Sigler, Holly G Prigerson, Allison J Applebaum, and Eli L Diamond

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Risk Factors of Long-Term Opioid Use After Elective Cervical and Lumbar Spine Surgery: A Michigan Spine Surgery Improvement Collaborative Study, Enoch Kim, Dheeraj Kagithala, Jianhui Hu, Kari Jarabek, Matthew Brennan, Anisse N. Chaker, Jacob Pawloski, Edvin Telemi, Tarek Mansour, Maria Cielito Robles, Hassan A. Fadel, Kylie Springer, Lonni Schultz, David R. Nerenz, Jad G. Khalil, Richard Easton, Miguelangelo Perez-Cruet, Ilyas Aleem, Paul Park, Teck Soo, Doris Tong, Muwaffak Abdulhak, Jason M. Schwalb, and Victor Chang

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Proteomic-based stemness score measures oncogenic dedifferentiation and enables the identification of druggable targets, Iga Kołodziejczak-Guglas, Renan L S Simões, Emerson de Souza Santos, Elizabeth G Demicco, Rossana N Lazcano Segura, Weiping Ma, Pei Wang, Yifat Geffen, Erik Storrs, Francesca Petralia, Antonio Colaprico, Felipe da Veiga Leprevost, Pietro Pugliese, Michele Ceccarelli, Houtan Noushmehr, Alexey I Nesvizhskii, Bożena Kamińska, Waldemar Priebe, Jan Lubiński, Bing Zhang, Alexander J Lazar, Paweł Kurzawa, Mehdi Mesri, Ana I Robles, Li Ding, Tathiane M Malta, and Maciej Wiznerowicz

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A pilot survey into the landscape of neuro-oncology care in the community, Christine Lu-Emerson, Sajeel Chowdhary, Rupesh Kotecha, Akanksha Sharma, Yazmin Odia, Brian Vaillant, Charles Redfern, Aaron Mammoser, Kent Shih, Santosh Kesari, Richard Peterson, Bret Friday, W Jeffery Edenfield, Sebastian Koga, James Snyder, Jerry Jaboin, Isaac Melguizo-Gavilanes, Melissa McCabe, Michael Humeniuk, Prakash Ambady, and Erin Dunbar

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Stereotactic radiosurgery for patients with brain metastases: current principles, expanding indications and opportunities for multidisciplinary care, Alireza Mansouri, Ahmad Ozair, Debarati Bhanja, Hannah Wilding, Elad Mashiach, Waqas Haque, Nicholas Mikolajewicz, Leonardo de Macedo Filho, Sean S Mahase, Mitchell Machtay, Philippe Metellus, Frédéric Dhermain, Jason Sheehan, Douglas Kondziolka, L Dade Lunsford, Ajay Niranjan, Giuseppe Minniti, Jing Li, Steven N. Kalkanis, Patrick Y Wen, Rupesh Kotecha, Michael W McDermott, Chetan Bettegowda, Graeme F Woodworth, Paul D Brown, Arjun Sahgal, and Manmeet S Ahluwalia

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ReNeu: A Pivotal, Phase IIb Trial of Mirdametinib in Adults and Children With Symptomatic Neurofibromatosis Type 1-Associated Plexiform Neurofibroma, Christopher L Moertel, Angela C Hirbe, Hans H Shuhaiber, Kevin Bielamowicz, Alpa Sidhu, David Viskochil, Michael D Weber, Armend Lokku, L Mary Smith, Nicholas K Foreman, Fouad M Hajjar, Rene Y McNall-Knapp, Lauren Weintraub, Reuben Antony, Andrea T Franson, Julia Meade, David Schiff, Tobias Walbert, Prakash Ambady, Daniela A Bota, Cynthia J Campen, Gurcharanjeet Kaur, Laura J Klesse, Stefania Maraka, Paul L Moots, Kathryn Nevel, Miriam Bornhorst, Ana Aguilar-Bonilla, Sarah Chagnon, Nagma Dalvi, Punita Gupta, Ziad Khatib, Laura K Metrock, P Leia Nghiemphu, Ryan D Roberts, Nathan J Robison, Zsila Sadighi, Stacie Stapleton, Dusica Babovic-Vuksanovic, and Timothy R Gershon

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A window-of-opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma, Veronica Rendo, Eudocia Q Lee, Connor Bossi, Nicholas Khuu, Michelle A Rudek, Sangita Pal, Narmen Azazmeh, Rumana Rashid, Jia-Ren Lin, Margaret Cusick, Abigail R N Reynolds, Auriole C R Fassinou, Georges Ayoub, Seth Malinowski, Emily Lapinskas, William Pisano, John Jeang, Sylwia A Stopka, Michael S Regan, Johan Spetz, Arati Desai, Frank Lieberman, Kamalakannan Palanichamy, Joy D Fisher, Kristine Pelton, Raymond Y Huang, Kristopher A Sarosiek, Louis B Nabors, Matthias Holdhoff, Neeraja Danda, Roy Strowd, Serena Desideri, Tobias Walbert, Xiaobu Ye, Arnab Chakravarti, Peter K Sorger, Sandro Santagata, Nathalie Y R Agar, Stuart A Grossman, Brian M Alexander, Patrick Y Wen, Keith L Ligon, and Rameen Beroukhim

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Enhancing the Use of 5-Aminolevulinic Acid in Fluorescence-guided Surgery for High-grade Glioma: An Expert Nurse Practitioner Opinion-based Approach, Lisa Scarpace, Nicole Archer, Michelle Belusic, Isabella Buonanno, Nini Eng, Alina Estevez, Jaclyn Garcia, and Alexandra Schaber

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Return to play following craniotomy for non-traumatic brain lesions, Jovanna A Tracz, Matthew L. Farmer, Mark Hughes, Debraj Mukherjee, and Paul M Brennan

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When survival is not enough-Quality of life as a decision endpoint for patients, Tobias Walbert

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Symptom management in isocitrate dehydrogenase mutant glioma, Tobias Walbert, Edward K Avila, Florien W Boele, Caroline Hertler, Christine Lu-Emerson, Pim B van der Meer, Katherine B Peters, Alasdair G Rooney, Jessica W Templer, and Johan A F Koekkoek

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A multi-institutional phase 1 clinical trial exploring upfront multimodal standard of care and combined immunotherapies for newly diagnosed glioblastoma, Patrick Y Wen, Andrea Manzanera, Caroline Duault, Edgar Gonzalez-Kozlova, Lenika Lopez, Stuart A Grossman, Xiaobu Ye, Joy Fisher, Ian Lee, Tobias Walbert, James Snyder, Steven Brem, Arati Desai, Stephen J Bagley, Chandana Kakani, Roy Strowd, Stephen Tatter, Adrian Laxton, Glenn Lesser, Nduka Amankulor, Frank Lieberman, Jan Drappatz, Megan Mantica, Dan Triggs, Cara Haymaker, Ignacio I Wistuba, Gheath Al-Atrash, Julia Mendoza Perez, Andrew Futreal, Latasha D Little, M D Habibul Islam, Dzifa Duose, Peixin Jiang, Alexandre Reuben, Sean E Lawler, Mina Pichavant, Andrew Gentles, Sean Bendall, Alex Kong, Christine Camacho, Diane Del Valle, Seunghee Kim-Schulze, Sacha Gnjatic, Elad Sharon, M Oskar Nowicki, Pierpaolo Peruzzi, Doug Lane, Estuardo Aguilar-Cordova, Laura K Aguilar, Garrett Nichols, Jessica Dwyer, Paul Peter Tak, Holden Maecker, Francesca Barone, and E Antonio Chiocca

Submissions from 2024

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New-onset as opposed to established atrial fibrillation as a risk factor for incident stroke, Hassan Aboul Nour, Ammar Jum'ah, Lonni Schultz, Muhammad Affan, Karam Gagi, Omar Choudhury, Megan Brady, Dawn Scozzarri, Fadi Nahab, Daniel J. Miller, and Stephan A. Mayer

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Evaluating the Base Excision Repair Inhibitor TRC102 and Temozolomide for Patients with Recurrent Glioblastoma in the Phase 2 Adult Brain Tumor Consortium Trial BERT, Manmeet S. Ahluwalia, Ahmad Ozair, Jan Drappatz, Xiaobu Ye, Sen Peng, Matthew Lee, Sanhita Rath, Harshil Dhruv, Yue Hao, Michael E. Berens, Tobias Walbert, Matthias Holdhoff, Glenn J. Lesser, Timothy F. Cloughesy, Andrew E. Sloan, Naoko Takebe, Marta Couce, David M. Peereboom, Burt Nabors, Patrick Y. Wen, Stuart A. Grossman, and Lisa R. Rogers

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Machine Learning-based Prognostic Subgrouping of Glioblastoma: A Multi-center Study, Hamed Akbari, Spyridon Bakas, Chiharu Sako, Anahita Fathi Kazerooni, Javier Villanueva-Meyer, Jose A Garcia, Elizabeth Mamourian, Fang Liu, Quy Cao, Russell T Shinohara, Ujjwal Baid, Alexander Getka, Sarthak Pati, Ashish Singh, Evan Calabrese, Susan Chang, Jeffrey Rudie, Aristeidis Sotiras, Pamela LaMontagne, Daniel S Marcus, Mikhail Milchenko, Arash Nazeri, Carmen Balana, Jaume Capellades, Josep Puig, Chaitra Badve, Jill S Barnholtz-Sloan, Andrew E Sloan, Vachan Vadmal, Kristin Waite, Murat Ak, Rivka R Colen, Yae Won Park, Sung Soo Ahn, Jong Hee Chang, Yoon Seong Choi, Seung-Koo Lee, Gregory S Alexander, Ayesha S Ali, Adam P Dicker, Adam E Flanders, Spencer Liem, Joseph Lombardo, Wenyin Shi, Gaurav Shukla, Brent Griffith, Laila M. Poisson, Lisa R. Rogers, Aikaterini Kotrotsou, Thomas C Booth, Rajan Jain, Matthew Lee, Abhishek Mahajan, Arnab Chakravarti, Joshua D Palmer, Dominic DiCostanzo, Hassan Fathallah-Shaykh, Santiago Cepeda, Orazio Santo Santonocito, Anna Luisa Di Stefano, Benedikt Wiestler, Elias R Melhem, Graeme F Woodworth, Pallavi Tiwari, Pablo Valdes, Yuji Matsumoto, Yoshihiro Otani, Ryoji Imoto, Mariam Aboian, Shinichiro Koizumi, Kazuhiko Kurozumi, Toru Kawakatsu, Kimberley Alexander, Laveniya Satgunaseelan, Aaron M Rulseh, Stephen J Bagley, Michel Bilello, Zev A Binder, Steven Brem, Arati S Desai, Robert A Lustig, Eileen Maloney, Timothy Prior, Nduka Amankulor, Mac Lean P Nasrallah, Donald M O'Rourke, Suyash Mohan, and Christos Davatzikos

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Clinical Implications of Pituitary Adenomas Exhibiting Dual Transcription Factor Staining: A Case Series of 27 Patients, Ilaria Bove, Stephanie K. Cheok, Jeffrey J. Feng, Robert G. Briggs, Jacob Ruzevick, David J. Cote, Ishan Shah, Andrew Little, Edward Laws, Anavaleria Castro, John Carmichael, Mark Shiroishi, Kyle Hurth, and Gabriel Zada

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A propensity score-matched comparison between single-stage and multistage anterior/posterior lumbar fusion surgery: a Michigan Spine Surgery Improvement Collaborative study, Anisse N. Chaker, Michael Melhem, Dheeraj Kagithala, Edvin Telemi, Tarek R. Mansour, Leticia Simo, Kylie Springer, Lonni Schultz, Kari Jarabek, Anneliese F. Rademacher, Matthew Brennan, Enoch Kim, David R. Nerenz, Jad G. Khalil, Richard Easton, Miguelangelo Perez-Cruet, Ilyas Aleem, Paul Park, Teck Soo, Doris Tong, Muwaffak M. Abdulhak, Jason M. Schwalb, and Victor Chang

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The impact of serum albumin levels on postoperative complications in lumbar and cervical spine surgery: an analysis of the Michigan Spine Surgery Improvement Collaborative registry, Anisse N. Chaker, Anneliese F. Rademacher, Matthew K. Easton, Yousif Jafar, Edvin Telemi, Tarek R. Mansour, Enoch Kim, Matthew Brennan, Jianhui Hu, Lonni Schultz, David R. Nerenz, Jason M. Schwalb, Muwaffak M. Abdulhak, Jad G. Khalil, Richard Easton, Miguelangelo Perez-Cruet, Ilyas Aleem, Paul Park, Teck Soo, Doris Tong, and Victor Chang

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Ipsilateral Nasoseptal Flaps in a Transpterygoid Approach: Technical Pearls and Reconstruction Outcomes, Michael T. Chang, David Grimm, Karam Asmaro, Michael Yong, Christopher Low, Christine K. Lee, Jayakar V. Nayak, Peter H. Hwang, Juan C. Fernandez-Miranda, and Zara M. Patel

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Vepoloxamer improves functional recovery in rat after traumatic brain injury: A dose-response and therapeutic window study, Liang Chen, Ye Xiong, Michael Chopp, Haiyan Pang, Marty Emanuele, Zhenggang Zhang, Asim Mahmood, and Yanlu Zhang

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Engineered exosomes enriched with select microRNAs amplify their therapeutic efficacy for traumatic brain injury and stroke, Liang Chen, Ye Xiong, Michael Chopp, and Yanlu Zhang

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Utility of an Untargeted Metabolomics Approach Using a 2D GC-GC-MS Platform to Distinguish Relapsing and Progressive Multiple Sclerosis, Indrani Datta, Insha Zahoor, Nasar Ata, Faraz Rashid, Mirela Cerghet, Ramandeep Rattan, Laila M. Poisson, and Shailendra Giri

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The impact of anxiety and depression on lumbar spine surgical outcomes: a Michigan Spine Surgery Improvement Collaborative study, Nachiket Deshpande, Moustafa Hadi, Tarek R. Mansour, Edvin Telemi, Travis Hamilton, Jianhui Hu, Lonni Schultz, David R. Nerenz, Jad G. Khalil, Richard Easton, Miguelangelo Perez-Cruet, Ilyas Aleem, Paul Park, Teck Soo, Doris Tong, Muwaffak M. Abdulhak, Jason M. Schwalb, and Victor Chang

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Diagnostic Accuracy of Beta-2 Transferrin Gel Electrophoresis for Detecting Cerebrospinal Fluid Rhinorrhea, Jacob G. Eide, William Mason, Hussein Mackie, Bernard Cook, Amrita Ray, Karam Asmaro, Adam Robin, Jack Rock, and John R Craig

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Factors Affecting Selection of TraineE for Neurointervention (FASTEN), Mohamed Elfil, Rami Z. Morsi, Sherief Ghozy, Ahmed Elmashad, Adnan Siddiqui, Alhamza R. Al-Bayati, Ali Alaraj, Allan Brook, Anthony W. Kam, Arindam Rano Chatterjee, Athos Patsalides, Ben Waldau, Charles J. Prestigiacomo, Charles Matouk, Clemens M. Schirmer, David Altschul, David T. Parrella, Gabor Toth, Gaurav Jindal, Hamza A. Shaikh, Jaydevsinh N. Dolia, Johanna T. Fifi, Justin F. Fraser, Justin Thomas, Krishna Amuluru, Louis J. Kim, Mark Harrigan, Matthew R. Amans, Max Kole, Max Mokin, Michael Abraham, Mouhammad Jumaa, Nazli Janjua, Osama Zaidat, Patrick P. Youssef, Priyank Khandelwal, Qingliang Tony Wang, Ramesh Grandhi, Ricardo Hanel, Ryan T. Kellogg, Santiago Ortega-Gutierrez, Sunil Sheth, Thanh N. Nguyen, Viktor Szeder, Yin C. Hu, Albert J. Yoo, Omar Tanweer, Brian Jankowitz, Jeremy J. Heit, Richard Williamson, Tareq Kass-Hout, Richard W. Crowley, Mohammad El-Ghanem, and Fawaz Al-Mufti

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Global neuro-oncology: what lies ahead for low- and middle-income countries?, Syed Ather Enam, Kee B. Park, Naureen Mushtaq, Muhammad Faraz Raghib, Fatima Mustansir, Mashal Murad Shah, Mohammad Hamza Bajwa, Minhal Faisal, Michael C. Dewan, Tariq Khan, and Jack P. Rock

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Laser interstitial thermal therapy for first-line treatment of insular glioma, Hassan A. Fadel, Jacob A. Pawloski, Anthony J. Anzalone, Sameah A. Haider, Lonni R. Schultz, Steven N. Kalkanis, Adam M. Robin, and Ian Y. Lee

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Letter to the Editor Regarding "The Accreditation Council for Graduate Medical Education (ACGME) Twenty-Year Trends in Diversity, Equity, and Inclusion (DEI) in the USA: How does Neurological Surgery compare?", Brian Foresi, Ellen L. Air, and Susan Pannullo

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Irradiation safety, anesthesia time, surgical complications, and patient-reported outcomes in the robotic Mazor X versus fluoroscopy guided minimally invasive transforaminal lumbar interbody fusion surgery: a comparative cohort study, Daniel W. Griepp, Joshua Caskey, Armando Bunjaj, Jeffrey Turnbull, Ammar H. Alsalahi, Hepzibha Alexander, James W. Dragonette, Bryce Sarcar, Shivum A. Desai, Doris Tong, Teck M. Soo, Peter Bono, Prashant Kelkar, Clifford M. Houseman, Chad F. Claus, Boyd F. Richards, and Daniel A. Carr

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Anatomic Review in 3D Augmented Reality Alters Craniotomy Planning Among Residents, Sameah A. Haider, Ellen L. Air, Zhifeng Kou, and Jack Rock

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Risk factors for not reaching minimal clinically important difference at 90 days and 1 year after elective lumbar spine surgery: a cohort study, Travis Hamilton, Seokchun Lim, Edvin Telemi, Ho Jun Yun, Mohamed Macki, Lonni Schultz, Hsueh-Han Yeh, Kylie Springer, Kevin Taliaferro, Miguelangelo Perez-Cruet, Ilyas Aleem, Paul Park, Richard Easton, David R. Nerenz, Jason M. Schwalb, Muwaffak M. Abdulhak, and Victor Chang

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Lisavanbulin (BAL101553), a Novel Microtubule Inhibitor, Plus Radiation in Patients with Newly Diagnosed, MGMT Promoter Unmethylated Glioblastoma, Matthias Holdhoff, Xiaobu Ye, Roy E Strowd, Burt Nabors, Tobias Walbert, Frank S Lieberman, Stephen J Bagley, John B Fiveash, Joy D Fisher, Serena Desideri, Trisha Surakus, Marc Engelhardt, Thomas Kaindl, Heidi A Lane, Karine Litherland, Stuart A Grossman, and Lawrence R Kleinberg

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Integration of Augmented Reality Into Glioma Resection Surgery: A Case Report, Rachel J. Hunt, Lisa Scarpace, and Jack Rock

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Intraoperative Augmented Reality for Complex Glioma Resection: A Case Report, Rachel J. Hunt, Lisa Scarpace, and Jack P. Rock

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Synthesis, Structure, and In Vitro Pharmacological Evaluation of some New Pyrimidine-2-Sulfonamide Derivatives and Their Molecular Docking Studies on Human Estrogen Receptor Alpha and CDK2/Cyclin Proteins, Qassim A. H. Jaber, Ahmed H. Shentaif, Mohammed Almajidi, Iqrar Ahmad, Harun Patel, Abul K. Azad, Sulaiman M. Alnasser, Hanan Ali Alatawi, Farid Menaa, Sulaiman Y. M. Alfaifi, Mohammed M. Rahman, Meser M. Ali, and S. J. Aditya Rao

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Why Pimping Works: The Neurophysiology of Emotional Memories, Med Jimson D. Jimenez, Pranish Kantak, and Jeffrey Raskin

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Augmented Reality Registration System for Visualization of Skull Landmarks, Pranish A. Kantak, Seamus Bartlett, Anisse Chaker, Samuel Harmon, Tarek Mansour, Jacob Pawloski, Edvin Telemi, Heegook Yeo, Samantha Winslow, Jonathan Cohen, Lisa Scarpace, Adam Robin, and Jack P. Rock

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Long-Term Treatment of Chronic Postamputation Pain With Bioelectric Nerve Block: Twelve-Month Results of the Randomized, Double-Blinded, Cross-Over QUEST Study, Leonardo Kapural, Billy Kim, John Eidt, Erika A. Petersen, Jason M. Schwalb, Konstantin V. Slavin, and Nagy Mekhail

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Primary 3-Month Outcomes of a Double-Blind Randomized Prospective Study (The QUEST Study) Assessing Effectiveness and Safety of Novel High-Frequency Electric Nerve Block System for Treatment of Post-Amputation Pain, Leonardo Kapural, Jim Melton, Billy Kim, Priyesh Mehta, Abindra Sigdel, Alexander Bautista, Erika A. Petersen, Konstantin V. Slavin, John Eidt, Jiang Wu, Said Elshihabi, Jason M. Schwalb, H. Edward Garrett, Elias Veizi, Giancarlo Barolat, Ravi R. Rajani, Peter C. Rhee, Maged Guirguis, and Nagy Mekhail

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Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model, Bryan D Kim, Sujan K Mondal, Elizabeth Kenyon, Ming Chen, Christiane L Mallett, Ana C de Carvalho, Zdravka Medarova, and Anna Moore

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Autologous cell immunotherapy (IGV-001) with IGF-1R antisense oligonucleotide in newly diagnosed glioblastoma patients, Ian Y. Lee, Simon Hanft, Michael Schulder, Kevin D. Judy, Eric T. Wong, J. Bradley Elder, Linton T. Evans, Mario Zuccarello, Julian Wu, Sonikpreet Aulakh, Vijay Agarwal, Rohan Ramakrishna, Brian J. Gill, Alfredo Quiñones-Hinojosa, Cameron Brennan, Brad E. Zacharia, Carlos Eduardo Silva Correia, Madhavi Diwanji, Gregory K. Pennock, Charles Scott, Raul Perez-Olle, David W. Andrews, and John A. Boockvar

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Raman-based machine learning platform reveals unique metabolic differences between IDHmut and IDHwt glioma, Adrian Lita, Joel Sjöberg, David Păcioianu, Nicoleta Siminea, Orieta Celiku, Tyrone Dowdy, Andrei Păun, Mark R. Gilbert, Houtan Noushmehr, Ion Petre, and Mioara Larion

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Compressive myelopathy from diffuse spinal dural calcifications in a patient with end-stage renal disease: illustrative case, Alexis Malecki, Jacob Pawloski, Anthony Anzalone, Kelly Shaftel, Hassan Fadel, and Ian Y. Lee

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The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen, Tathiane M. Malta, Thais S. Sabedot, Natalia S. Morosini, Indrani Datta, Luciano Garofano, Wies Vallentgoed, Frederick S. Varn, Kenneth Aldape, Fulvio D'Angelo, Spyridon Bakas, Jill S. Barnholtz-Sloan, Hui K. Gan, Mohammad Hasanain, Ann-Christin Hau, Kevin C. Johnson, Simona Cazacu, Ana C. de Carvalho, Mustafa Khasraw, Emre Kocakavuk, Mathilde C. M Kouwenhoven, Simona Migliozzi, Simone P. Niclou, Johanna M. Niers, D. Ryan Ormond, Sun Ha Paek, Guido Reifenberger, Peter A. Sillevis Smitt, Marion Smits, Lucy F. Stead, Martin J. van den Bent, Erwin G. Van Meir, Annemiek Walenkamp, Tobias Weiss, Michael Weller, Bart A. Westerman, Bauke Ylstra, Pieter Wesseling, Anna Lasorella, Pim J. French, Laila M. Poisson, Roel G. W Verhaak, Antonio Iavarone, and Houtan Noushmehr

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Phase 1b/2 study of orally administered pexidartinib in combination with radiation therapy and temozolomide in patients with newly diagnosed glioblastoma, Joe S Mendez, Adam L Cohen, Midori Eckenstein, Randy L Jensen, Lindsay M Burt, Karen L Salzman, Marc Chamberlain, Henry H Hsu, Marguerite Hutchinson, Fabio Iwamoto, Keith L Ligon, Maciej M Mrugala, Michael Pelayo, Scott R Plotkin, Vinay K Puduvalli, Jeffrey Raizer, David A Reardon, Michael Sterba, Tobias Walbert, Brian L West, Eric T Wong, Chao Zhang, and Howard Colman

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Genome-Wide DNA Methylation Profiling as a Prognostic Marker in Pituitary Adenomas-A Pilot Study, Morten Winkler Møller, Marianne Skovsager Andersen, Bo Halle, Christian Bonde Pedersen, Henning Bünsow Boldt, Qihua Tan, Philipp Sebastian Jurmeister, Grayson A. Herrgott, Ana V. Castro, Jeanette K. Petersen, and Frantz Rom Poulsen

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Optimal Frequency in Repetitive Transcranial Magnetic Stimulation for the Management of Chronic Pain: A Network Meta-Analysis of Randomized Controlled Trials, Anant Naik, Momodou Bah, Mukul Govande, Peggy Palsgaard, Rajiv Dharnipragada, Annabelle Shaffer, Ellen L. Air, Samuel W. Cramer, Paul E. Croarkin, and Paul M. Arnold

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Risk factors of emergency department visits following elective cervical and lumbar surgical procedures: a multi-institution analysis from the Michigan Spine Surgery Improvement Collaborative, Oludotun Ogunsola, Joseph R. Linzey, Mark M. Zaki, Victor Chang, Lonni R. Schultz, Kylie Springer, Muwaffak M. Abdulhak, Jad G. Khalil, Jason M. Schwalb, Ilyas Aleem, David R. Nerenz, Miguelangelo Perez-Cruet, Richard Easton, Teck M. Soo, Doris Tong, and Paul Park

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The AANS/CNS Section on Tumors: a summary of 40 years of advocacy to advance the care of patients with brain and spine tumors, Ian F. Parney, Ronald E. Warnick, Frederick F. Lang, James T. Rutka, Steven N. Kalkanis, Roberta Glick, Mark L. Rosenblum, and Isabelle M. Germano

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Discontinuation of Antiseizure Medications in Patients With Brain Tumors, Katherine B. Peters, Jessica Templer, Elizabeth R. Gerstner, Thomas Wychowski, Anette M. Storstein, Karan Dixit, Tobias Walbert, Kaitlyn Melnick, Maya Hrachova, Sonia Partap, Nicole J. Ullrich, Ashley P. Ghiaseddin, and Maciej Mrgula

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Clinical safety and feasibility of a novel implantable neuroimmune modulation device for the treatment of rheumatoid arthritis: initial results from the randomized, double-blind, sham-controlled RESET-RA study, Daniel Peterson, Mark Van Poppel, Warren Boling, Perry Santos, Jason M. Schwalb, Howard Eisenberg, Ashesh Mehta, Heather Spader, James Botros, Frank D. Vrionis, Andrew Ko, P. David Adelson, Bradley Lega, Peter Konrad, Guillermo Calle, Fernando L. Vale, Richard Bucholz, and R. Mark Richardson

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Laser Interstitial Thermal Therapy for Intra-Axial Brain Tumors: Everything the Neuroradiologist Should Know, Anneliese F. Rademacher, Hassan A. Fadel, Jacob A. Pawloski, Mia Ma, Kenneth Nkongchu, Ian Y. Lee, and Arafat Y. Ali

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Laser interstitial thermal therapy for deep-seated perivascular brain tumors is not associated with distal ischemia, Jared C. Reese, Hassan A. Fadel, Jacob A. Pawloski, Mariam Samir, Sameah A. Haider, Ricardo J. Komatar, Evan Luther, Alexis A. Morell, Mike E. Ivan, Adam M. Robin, Steven N. Kalkanis, and Ian Y. Lee

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A rare case of double pituitary prolactinomas: the diagnostic application of intraoperative ultrasonography and DNA methylation markers, Jared C. Reese, Thomas M. Zervos, Jack Rock, Abeer Z. Tabbarah, Houtan Noushmehr, Grayson A. Herrgott, and Ana V. Castro

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Heterogeneous Mechanical Stress and Interstitial Fluid Flow Predictions Derived from DCE-MRI for Rat U251N Orthotopic Gliomas, Julian A. Rey, Katelynn G. Spanick, Glauber Cabral, Isabel N. Rivera-Santiago, Tavarekere N. Nagaraja, Stephen L. Brown, James R. Ewing, and Malisa Sarntinoranont

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American Association of Neurological Surgeons/Congress of the Neurological Surgeons Section on Tumors Guidelines: Assessing Their Impact on Brain Tumor Clinical Practice, Faith C. Robertson, Brian V. Nahed, Garni Barkhoudarian, Anand Veeravagu, David Berg, Steven N. Kalkanis, Jeffrey J. Olson, and Isabelle M. Germano

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Integration of Mixed Reality Technology Into a Global Neurosurgery Bootcamp, Jack P. Rock, Lonni Schultz, Robert Dempsey, and Jonathan Cohen

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Toward Standardized Brain Tumor Ttissue Processing Protocols in Neuro-Oncology: A Perspective for Gliomas and Beyond, Analiz Rodriguez, Manmeet S Ahluwalia, Chetan Bettegowda, Henry Brem, Bob S Carter, Susan Chang, Sunit Das, Charles Eberhart, Tomas Garzon-Muvdi, Costas G Hadjipanayis, Cynthia Hawkins, Thomas S Jacques, Alexander A Khalessi, Michael W McDermott, Tom Mikkelsen, Brent A Orr, Joanna J Phillips, Mark Rosenblum, William J Shelton, David A Solomon, Andreas von Deimling, Graeme F Woodworth, and James T Rutka

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Virtual multi-institutional tumor board: a strategy for personalized diagnoses and management of rare CNS tumors, James L. Rogers, Thomas Wall, Alvina A. Acquaye-Mallory, Lisa Boris, Yeonju Kim, Kenneth Aldape, Martha M. Quezado, John A. Butman, James G. Smirniotopoulos, Huma Chaudhry, Christina I. Tsien, Prashant Chittiboina, Kareem Zaghloul, Orwa Aboud, Nicholas G. Avgeropoulos, Eric C. Burton, David M. Cachia, Karan S. Dixit, Jan Drappatz, Erin M. Dunbar, Peter Forsyth, Edina Komlodi-Pasztor, Jacob Mandel, Byram H. Ozer, Eudocia Q. Lee, Surabhi Ranjan, Rimas V. Lukas, Margarita Raygada, Michael E. Salacz, Matthew A. Smith-Cohn, James Snyder, Ariane Soldatos, Brett J. Theeler, Brigitte C. Widemann, Kevin A. Camphausen, John D. Heiss, Terri S. Armstrong, Mark R. Gilbert, and Marta Penas-Prado

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Phase I and pharmacodynamic study of arsenic trioxide plus radiotherapy in patients with newly diagnosed glioblastoma, Samuel Ryu, Xiaobu Ye, Jeffrey J. Olson, Tom Mikkelsen, Lev Bangiyev, Glenn J. Lesser, Tracy Batchelor, Burt Nabors, Serena Desideri, Tobias Walbert, and Stuart A. Grossman

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Variation in Cone Beam Computed Tomography Utilization and Radiation Exposure Associated with Prostatic Artery Embolization on Two Separate Angiography Systems, Abin Sajan, Daniel W. Griepp, and Ari J. Isaacson

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Building Neurosurgical Capacity in Myanmar with Parallel Twinning Programs by US and Swiss Teams, Philippe Schucht, Jack P. Rock, Su Myat Mo, Kyi Hlaing, Win Myaing, Myat Thu, Khin Maung Lwin, Kyawzwar Aung, Dominique Kuhlen, and Zaw Wai Soe

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Does Tighter Glycemic Control Beyond Hemoglobin A1c of 8% Improve Outcome for Lumbar Spine Surgery? A MSSIC Study, Edvin Telemi, Tarek R. Mansour, Matthew Brennan, Leticia Simo, Jianhui Hu, Lonni Schultz, David R. Nerenz, Jad G. Khalil, Richard Easton, Miguelangelo Perez-Cruet, Ilyas Aleem, Paul Park, Teck Soo, Doris Tong, Muwaffak M. Abdulhak, Jason M. Schwalb, and Victor Chang

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The biological significance of tumor grade, age, enhancement, and extent of resection in IDH-mutant gliomas: How should they inform treatment decisions in the era of IDH inhibitors?, Martin J. van den Bent, Pim J. French, Daniel Brat, Joerg C. Tonn, Mehdi Touat, Benjamin M. Ellingson, Robert J. Young, Johan Pallud, Andreas von Deimling, Felix Sahm, Dominique Figarella Branger, Raymond Y. Huang, Michael Weller, Ingo K. Mellinghoff, Tim F. Cloughsey, Jason T. Huse, Kenneth Aldape, Guido Reifenberger, Gilbert Youssef, Philipp Karschnia, Houtan Noushmehr, Katherine B. Peters, Francois Ducray, Matthias Preusser, and Patrick Y. Wen

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Prospective assessment of end-of-life symptoms and quality of life in patients with high-grade glioma, Tobias Walbert, Lonni Schultz, Tom Mikkelsen, James Snyder, Joel Phillips, and John T. Fortunato

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Continuing Education for Global Neurosurgery Graduates: Visiting Surgeons, Skills Teaching, Bootcamps, and Twinning Programs, Julie Woodfield, Jared C. Reese, Roger Hartl, and Jack Rock

Submissions from 2023

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DeepInfusion: A dynamic infusion based-neuro-symbolic AI model for segmentation of intracranial aneurysms, Iram Abdullah, Ali Javed, Khalid Mahmood Malik, and Ghaus Malik

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Endoglin inhibitor TRC105 with or without bevacizumab for bevacizumab-refractory glioblastoma (ENDOT): a multicenter phase II trial, Manmeet S. Ahluwalia, Lisa Rogers, Rekha Chaudhary, Herbert Newton, Ahmad Ozair, Atulya A. Khosla, Andrew B. Nixon, Bonne J. Adams, Ben K. Seon, David M. Peereboom, and Charles P. Theuer

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Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma, Wajd N. Al-Holou, Hanxiao Wang, Visweswaran Ravikumar, Sunita Shankar, Morgan Oneka, Ziad Fehmi, Roel Gw Verhaak, Hoon Kim, Drew Pratt, Sandra Camelo-Piragua, Corey Speers, Daniel R. Wahl, Todd Hollon, Oren Sagher, Jason A. Heth, Karin M. Muraszko, Theodore S. Lawrence, Ana C. de Carvalho, Tom Mikkelsen, Arvind Rao, and Alnawaz Rehemtulla

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History and Future of Spinal Cord Stimulation, Rushna Ali and Jason M. Schwalb

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Editorial: Surgical techniques for the management of pain, Anthony K. Allam, Ashwin Viswanathan, Jason M. Schwalb, Parag G. Patil, and M. Benjamin Larkin

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Survey of United States neurosurgeons on firearm injury prevention, Megan G. Anderson, Amirul Anuar, Krystal L. Tomei, Jason M. Schwalb, Katie O. Orrico, Dimitri Sigounas, Ross C. Puffer, Michael A. Bohl, Russell R. Lonser, and Jonathan E. Martin

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Cytodifferentiation of pituitary tumors influences pathogenesis and cavernous sinus invasion, Karam Asmaro, Michael Zhang, Adrian J. Rodrigues, Ahmed Mohyeldin, Vera Vigo, Kerem Nernekli, Hannes Vogel, Donald E. Born, Laurence Katznelson, and Juan C. Fernandez-Miranda

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Radiomics characterization of tissues in an animal brain tumor model imaged using dynamic contrast enhanced (DCE) MRI, Hassan Bagher-Ebadian, Stephen L. Brown, Mohammad M. Ghassemi, Tavarekere N. Nagaraja, Benjamin Movsas, James R. Ewing, and Indrin J. Chetty

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Dynamic contrast enhanced (DCE) MRI estimation of vascular parameters using knowledge-based adaptive models, Hassan Bagher-Ebadian, Stephen L. Brown, Mohammad M. Ghassemi, Tavarekere N. Nagaraja, Olivia G. Valadie, Prabhu C. Acharya, Glauber Cabral, George Divine, Robert A. Knight, Ian Y. Lee, Jun Xu, Benjamin Movsas, Indrin J. Chetty, and James R. Ewing

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Persistent Peri-Ablation Blood-Brain Barrier Opening After Laser Interstitial Thermal Therapy for Brain Tumors., Seamus Bartlett, Tavarekere N. Nagaraja, Brent Griffith, Katelynn G. Farmer, Meredith Van Harn, Sameah A. Haider, Rachel J. Hunt, Glauber Cabral, Robert A. Knight, Olivia G. Valadie, Stephen L. Brown, James R. Ewing, and Ian Y. Lee

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Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas., Markus Bredel, Lluís Espinosa, Hyunsoo Kim, Denise M. Scholtens, Joseph P. McElroy, Rajani Rajbhandari, Wei Meng, Thomas M. Kollmeyer, Tathiane M. Malta, Michael A. Quezada, Griffith R. Harsh, Teresa Lobo-Jarne, Laura Solé, Aran Merati, Surya Nagaraja, Sindhu Nair, Jaclyn J. White, Nanda K. Thudi, Jessica L. Fleming, Amy Webb, Atsushi Natsume, Seishi Ogawa, Ruthild G. Weber, Joan Bertran, S. Jaharul Haque, Bettina Hentschel, C. Ryan Miller, Frank B. Furnari, Timothy A. Chan, Anca-Ligia Grosu, Michael Weller, Jill S. Barnholtz-Sloan, Michelle Monje, Houtan Noushmehr, Robert B. Jenkins, C. Leland Rogers, David R. MacDonald, Stephanie L. Pugh, and Arnab Chakravarti

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Multiorganizational consensus to define guiding principles for perioperative pain management in patients with chronic pain, preoperative opioid tolerance, or substance use disorder, David M. Dickerson, Edward R. Mariano, Joseph W. Szokol, Michael Harned, Randall M. Clark, Jeffrey T. Mueller, Ashley M. Shilling, Mercy A. Udoji, S. Bobby Mukkamala, Lisa Doan, Karla E. K Wyatt, Jason M. Schwalb, Nabil M. Elkassabany, Jean D. Eloy, Stacy L. Beck, Lisa Wiechmann, Franklin Chiao, Steven G. Halle, Deepak G. Krishnan, John D. Cramer, Wael Ali Sakr Esa, Iyabo O. Muse, Jaime Baratta, Richard Rosenquist, Padma Gulur, Shalini Shah, Lynn Kohan, Jennifer Robles, Eric S. Schwenk, Brian F. S Allen, Stephen Yang, Josef G. Hadeed, Gary Schwartz, Michael J. Englesbe, Michael Sprintz, Kenneth L. Urish, Ashley Walton, Lauren Keith, and Asokumar Buvanendran

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In Reply: Laser Interstitial Thermal Therapy for First-Line Treatment of Surgically Accessible Recurrent Glioblastoma: Outcomes Compared With a Surgical Cohort, Hassan A. Fadel, Jacob A. Pawloski, and Ian Y. Lee

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Artificial intelligence improves transfer times and ischemic stroke workflow metrics, Nicholas C. Field, Pouya Entezami, Alan S. Boulos, John Dalfino, and Alexandra R. Paul

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Targeted sequencing of cancer-related genes reveals a recurrent TOP2A variant which affects DNA binding and coincides with global transcriptional changes in glioblastoma, Bartlomiej Gielniewski, Katarzyna Poleszak, Adria-Jaume Roura, Paulina Szadkowska, Karol Jacek, Sylwia K. Krol, Rafal Guzik, Paulina Wiechecka, Marta Maleszewska, Beata Kaza, Andrzej Marchel, Tomasz Czernicki, Andrzej Koziarski, Grzegorz Zielinski, Andrzej Styk, Maciej Kawecki, Cezary Szczylik, Ryszard Czepko, Mariusz Banach, Wojciech Kaspera, Wojciech Szopa, Mateusz Bujko, Bartosz Czapski, Miroslaw Zabek, Ewa Iżycka-Świeszewska, Wojciech Kloc, Pawel Nauman, Joanna Cieslewicz, Wieslawa Grajkowska, Natalia S. Morosini, Houtan Noushmehr, Bartosz Wojtas, and Bozena Kaminska

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Commentary: Prone Transpsoas Lateral Lumbar Interbody Fusion for Degenerative Lumbar Spine Disease: Case Series With an Operative Video Using Fluoroscopy-Based Instrument Tracking Guidance, Moustafa Hadi, Nachiket Deshpande, Travis Hamilton, and Victor Chang

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Association of prolonged symptom duration with poor outcomes in lumbar spine surgery: a Michigan Spine Surgery Improvement Collaborative study, Travis Hamilton, Seamus Bartlett, Nachiket Deshpande, Moustafa Hadi, Jared C. Reese, Tarek R. Mansour, Edvin Telemi, Kylie Springer, Lonni Schultz, David R. Nerenz, Muwaffak M. Abdulhak, Teck Soo, Jason M. Schwalb, Jad G. Khalil, Ilyas Aleem, Richard Easton, Miguelangelo Perez-Cruet, Paul Park, and Victor Chang

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Detection of diagnostic and prognostic methylation-based signatures in liquid biopsy specimens from patients with meningiomas, Grayson A. Herrgott, James M. Snyder, Ruicong She, Tathiane M. Malta, Thais S. Sabedot, Ian Y. Lee, Jacob Pawloski, Guilherme G. Podolsky-Gondim, Karam P. Asmaro, Jiaqi Zhang, Cara E. Cannella, Kevin K. Nelson, Bartow Thomas, Ana C. de Carvalho, Laura A. Hasselbach, Kelly M. Tundo, Rehnuma Newaz, Andrea D. Transou, Natalia S. Morosini, Victor Francisco, Laila M. Poisson, Dhananjay A. Chitale, Abir Mukherjee, Maritza S. Mosella, Adam M. Robin, Tobias Walbert, Mark Rosenblum, Tom Mikkelsen, Steven N. Kalkanis, Daniela P. C Tirapelli, Daniel J. Weisenberger, Carlos G. Carlotti, Jack Rock, Ana V. Castro, and Houtan Noushmehr

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StrokeNet: An automated approach for segmentation and rupture risk prediction of intracranial aneurysm, Muhammad Irfan, Khalid Mahmood Malik, Jamil Ahmad, and Ghaus Malik

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The Duration of Symptoms Influences Outcomes After Lumbar Microdiscectomies: A Michigan Spine Surgery Improvement Collaborative, Rafid Kasir, Philip Zakko, Sazid Hasan, Ilyas Aleem, Daniel Park, David R. Nerenz, Muwaffak M. Abdulhak, Mick Perez-Cruz, Jason M. Schwalb, Ehab S. Saleh, Richard Easton, and Jad G. Khalil

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Development of Curcumin and Piperine-Loaded Bio-Active Self-Nanoemulsifying Drugs and Investigation of Their Bioactivity in Zebrafish Embryos and Human Hematological Cancer Cell Lines, Mohsin Kazi, Muhammad Farooq Khan, Fahd A. Nasr, Mohammad Z. Ahmed, Ali S. Alqahtani, Meser M. Ali, and Mohammed S. Aldughaim

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Bone Grafting Options for Single-Level TLIF: So Many Options, What Is the Evidence?, Enoch Kim, Matthew Brennan, Pavithra Margabandu, Nicole Oska, Maria Robles, Anneliese Rademacher, Edvin Telemi, Tarek Mansour, and Victor W. Chang

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Hemizygous CDKN2A deletion confers worse survival outcomes in IDHmut-noncodel gliomas, Emre Kocakavuk, Kevin C. Johnson, Thais S. Sabedot, Hans Christian Reinhardt, Houtan Noushmehr, and Roel G. W Verhaak

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Reply to the letter regarding "Palliative care and end-of-life care in adults with malignant brain tumors"., Johan A. F Koekkoek, Pim B. van der Meer, and Tobias Walbert

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Preoperative validation of edema-corrected tractography in neurosurgical practice: translating surgeon insights into novel software implementation, Sebastian F. Koga, Wesley B. Hodges, Hayk Adamyan, Tim Hayes, Peter E. Fecci, Vadim Tsvankin, Gustavo Pradilla, Kimberly B. Hoang, Ian Y. Lee, Eric W. Sankey, Patrick J. Codd, David Huie, Brad E. Zacharia, Ragini Verma, and Vatche G. Baboyan

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Identification of Environmental Exposures Associated with Risk of Sarcoidosis in African Americans, Albert M. Levin, Ruicong She, Yalei Chen, Indra Adrianto, Indrani Datta, Ian M. Loveless, Lori Garman, Courtney G. Montgomery, Jia Li, Michael Iannuzzi, and Benjamin A. Rybicki

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The Potential Negative Effects of Smoking on Cervical and Lumbar Surgery beyond Pseudoarthrosis: A Michigan Spine Surgery Improvement Collaborative (MSSIC) Study, Seokchun Lim, Lonni Schultz, Philip Zakko, Mohamed Macki, Travis Hamilton, Jacob Pawloski, Hassan Fadel, Tarek Mansour, Hsueh-Han Yeh, Gordon Preston, David R. Nerenz, Jason M. Schwalb, Muwaffak M. Abdulhak, Paul Park, Ilyas Aleem, Richard Easton, Jad Khalil, Miguelangelo Perez-Cruet, Daniel Park, and Victor Chang