Scholarly journal articles authored by members of the Division of Hematology/Oncology and the Henry Ford Cancer Institute at Henry Ford Health.

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Submissions from 2024

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Clinical Trials for Patients With Cancer, Fawzi Abu Rous, Aakash Desai, and Eric K. Singhi

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Modeling Molecular Pathogenesis of Idiopathic Pulmonary Fibrosis-Associated Lung Cancer in Mice, Ivana Barravecchia, Jennifer M. Lee, Jason Manassa, Brian Magnuson, Sarah F. Ferris, Sophia Cavanaugh, Nina G. Steele, Carlos E. Espinoza, Craig J. Galban, Nithya Ramnath, Timothy L. Frankel, Marina Pasca di Magliano, and Stefanie Galban

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Assessment of prostate tissue remodeling in rats exposed to bisphenol A and the phytoestrogens genistein and indole-3-carbinol during the perinatal period, Ericka S. B. Bueno, Carlos D. V. Neto, Alessandro Rodrigues, Thaina C. Sousa, Karianne D. Hinokuma, Ariana M. de Aquino, Wllerson R. Scarano, Joyce Z. Brandt, and Leonardo de Oliveira Mendes

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The impact of cancer metastases on COVID-19 outcomes: A COVID-19 and Cancer Consortium registry-based retrospective cohort study, Cecilia A. Castellano, Tianyi Sun, Deepak Ravindranathan, Clara Hwang, Nino Balanchivadze, Sunny R. K Singh, Elizabeth A. Griffiths, Igor Puzanov, Erika Ruiz-Garcia, Diana Vilar-Compte, Ana I. Cárdenas-Delgado, Rana R. McKay, Taylor K. Nonato, Archana Ajmera, Peter P. Yu, Rajani Nadkarni, Timothy E. O'Connor, Stephanie Berg, Kim Ma, Dimitrios Farmakiotis, Kendra Vieira, Panos Arvanitis, Renee M. Saliby, Chris Labaki, Talal El Zarif, Trisha M. Wise-Draper, Olga Zamulko, Ningjing Li, Brianne E. Bodin, Melissa K. Accordino, Matthew Ingham, Monika Joshi, Hyma V. Polimera, Leslie A. Fecher, Christopher R. Friese, James J. Yoon, Blanche H. Mavromatis, Jacqueline T. Brown, Karen Russell, Rahul Nanchal, Harpreet Singh, Lisa Tachiki, Feras A. Moria, Gayathri Nagaraj, Kimberly Cortez, Saqib H. Abbasi, Elizabeth M. Wulff-Burchfield, Matthew Puc, Lisa B. Weissmann, Padmanabh S. Bhatt, Melissa G. Mariano, Sanjay Mishra, Susan Halabi, Alicia Beeghly, Jeremy L. Warner, Benjamin French, and Mehmet A. Bilen

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Non-alcoholic Wernicke's Encephalopathy Masquerading As CNS Relapse of Acute Myeloid Leukemia, Ammad J. Chaudhary, Katherine M. Joyce, Kamran Haq, Muhammad H. Qureshi, and Vijayalakshmi Donthireddy

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Amivantamab plus Lazertinib in Previously Untreated EGFR-Mutated Advanced NSCLC, Byoung C. Cho, Shun Lu, Enriqueta Felip, Alexander I. Spira, Nicolas Girard, Jong-Seok Lee, Se-Hoon Lee, Yurii Ostapenko, Pongwut Danchaivijitr, Baogang Liu, Adlinda Alip, Ernesto Korbenfeld, Josiane Mourão Dias, Benjamin Besse, Ki-Hyeong Lee, Hailin Xiong, Soon-Hin How, Ying Cheng, Gee-Chen Chang, Hiroshige Yoshioka, James C-H Yang, Michael Thomas, Danny Nguyen, Sai-Hong I. Ou, Sanjay Mukhedkar, Kumar Prabhash, Manolo D'Arcangelo, Jorge Alatorre-Alexander, Juan C. Vázquez Limón, Sara Alves, Daniil Stroyakovskiy, Marina Peregudova, Mehmet A. N. Şendur, Ozan Yazici, Raffaele Califano, Vanesa Gutiérrez Calderón, Filippo de Marinis, Antonio Passaro, Sang-We Kim, Shirish M. Gadgeel, John Xie, Tao Sun, Melissa Martinez, Mariah Ennis, Elizabeth Fennema, Mahesh Daksh, Dawn Millington, Isabelle Leconte, Ryota Iwasawa, Patricia Lorenzini, Mahadi Baig, Sujay Shah, Joshua M. Bauml, S. Martin Shreeve, Seema Sethi, Roland E. Knoblauch, and Hidetoshi Hayashi

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Failure to Undergo Resection Following Neoadjuvant Therapy for Resectable Pancreatic Cancer: A Secondary Analysis of SWOG S1505, Jordan M. Cloyd, Sarah Colby, Katherine A. Guthrie, Andy M. Lowy, E. Gabrielle Chiorean, Philip A. Philip, Davendra Sohal, and Syed Ahmad

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Images in Immunotherapy and Precision Oncology: A Case Report of Neurofibromatosis-1, Anagha Deshpande, Javier Munoz, Vrushali Dabak, Amr Hanbali, and Razelle Kurzrock

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High-dose alectinib for RET fusion-positive non-small cell lung cancer in the Blood First Assay Screening Trial, Rafal Dziadziuszko, Nir Peled, Tony Mok, Solange Peters, Santiago Ponce Aix, Jorge Alatorre-Alexander, Brian D. Vicuna, Margaret Maclennan, Vijay Bhagawati-Prasad, Sarah M. Shagan, Erica Schleifman, Thorsten Ruf, Michael S. Mathisen, and Shirish M. Gadgeel

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Amivantamab plus lazertinib versus osimertinib in first-line EGFR-mutant advanced non-small-cell lung cancer with biomarkers of high-risk disease: a secondary analysis from MARIPOSA, E. Felip, B. C. Cho, V. Gutiérrez, A. Alip, B. Besse, S. Lu, A. I. Spira, N. Girard, R. Califano, Shirish M. Gadgeel, J. C-H Yang, S. Yamamoto, K. Azuma, Y. J. Kim, K-H Lee, P. Danchaivijitr, C. G. Ferreira, Y. Cheng, M. A. N. Sendur, G-C Chang, C-C Wang, K. Prabhash, Y. Shinno, D. Stroyakovskiy, L. Paz-Ares, J. R. Rodriguez-Cid, C. Martin, M. R. G. Campelo, H. Hayashi, D. Nguyen, P. Tomasini, M. Gottfried, C. Dooms, A. Passaro, M. Schuler, A. C. Z. Gelatti, S. Owen, K. Perdrizet, S-H I. Ou, J. C. Curtin, J. Zhang, M. Gormley, T. Sun, A. Panchal, M. Ennis, E. Fennema, M. Daksh, S. Sethi, J. M. Bauml, and S-H Lee

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Rethinking the Roles of Cancer-Associated Fibroblasts in Pancreatic Cancer, Ralph Francescone, Howard C. Crawford, and Débora Barbosa Vendramini Costa

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Frontline pembrolizumab monotherapy for metastatic non-small cell lung cancer with PD-L1 expression ≥50%: real-world outcomes in a US community oncology setting, Shirish M. Gadgeel, Pragya Rai, Srinivas Annavarapu, Sartaj Alam, Jerome H. Goldschmidt, Howard Jack West, Melissa Santorelli, and Renata Eiras Martins

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Pembrolizumab Plus Chemotherapy for Metastatic NSCLC With Programmed Cell Death Ligand 1 Tumor Proportion Score Less Than 1%: Pooled Analysis of Outcomes After Five Years of Follow-Up, Shirish M. Gadgeel, Delvys Rodríguez-Abreu, Balazs Halmos, Marina C. Garassino, Takayasu Kurata, Ying Cheng, Erin Jensen, Mark Shamoun, Kumar Rajagopalan, and Luis Paz-Ares

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Small molecular inhibitors: Therapeutic strategies for pancreatic cancer, Yuvasri Golivi, Seema Kumari, Batoul Farran, Afroz Alam, Sujatha Peela, and Ganji Purnachandra Nagaraju

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ALK Rearrangement Positive Lung Adenocarcinoma in Pregnancy Treated With Alectinib: A Case Report, Luis F. Gonzalez Mosquera, Fawzi Abu Rous, Alexandra Rogers, Nicolina Smith, Gregory Goyert, and Shirish M. Gadgeel

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Phase I Study of Fianlimab, a Human Lymphocyte Activation Gene-3 (LAG-3) Monoclonal Antibody, in Combination With Cemiplimab in Advanced Melanoma, Omid Hamid, Karl D. Lewis, Amy Weise, Meredith McKean, Kyriakos P. Papadopoulos, John Crown, Tae Min Kim, Dae Ho Lee, Sajeve S. Thomas, Janice Mehnert, John Kaczmar, Nehal J. Lakhani, Kevin B. Kim, Mark R. Middleton, Guilherme Rabinowits, Alexander I. Spira, Melinda Yushak, Inderjit Mehmi, Fang Fang, Shuquan Chen, Jayakumar Mani, Vladimir Jankovic, Fang Wang, Nathalie Fiaschi, Laura Brennan, Anne Paccaly, Sheila Masinde, Mark Salvati, Matthew G. Fury, Glenn Kroog, Israel Lowy, and Giuseppe Gullo

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For Squamous Cancers, the Streetlamps Shine on Occasional Keys, Most Baskets Are Empty, and the Umbrellas Cannot Keep Us Dry: A Call for New Models in Precision Oncology, D. Neil Hayes, Oluchukwu Oluoha, and David L. Schwartz

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Race-Related Differences in Sipuleucel-T Response among Men with Metastatic Castrate-Resistant Prostate Cancer, Elisabeth I. Heath, Archana Thakur, Wei Chen, Clara Hwang, Channing J. Paller, Frank C. Cackowski, Julie L. Boerner, Lance Heilbrun, Melanie P. Smith, Dana L. Schalk, Amy Schienschang, Sarah A. Whitaker, Amanda Polend, Daryn Smith, Ulka N. Vaishampayan, Brenda Dickow, and Lawrence G. Lum

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Donor types and outcomes of transplantation in myelofibrosis: a CIBMTR study, Tania Jain, Noel Estrada-Merly, M. Queralt Salas, Soyoung Kim, Jakob DeVos, Min Chen, Xi Fang, Rajat Kumar, Marcio Andrade-Campos, Hany Elmariah, Vaibhav Agrawal, Mahmoud Aljurf, Ulrike Bacher, Talha Badar, Sherif M. Badawy, Karen Ballen, Amer Beitinjaneh, Vijaya Raj Bhatt, Christopher Bredeson, Zachariah DeFilipp, Bhagirathbhai Dholaria, Nosha Farhadfar, Shatha Farhan, Arpita P. Gandhi, Siddhartha Ganguly, Usama Gergis, Michael R. Grunwald, Nada Hamad, Betty K. Hamilton, Yoshihiro Inamoto, Madiha Iqbal, Omer Jamy, Mark Juckett, Mohamed A. Kharfan-Dabaja, Maxwell M. Krem, Deepesh P. Lad, Jane Liesveld, Monzr M. Al Malki, Adriana K. Malone, Hemant S. Murthy, Guillermo Ortí, Sagar S. Patel, Attaphol Pawarode, Miguel-Angel Perales, Marjolein van der Poel, Olle Ringden, David A. Rizzieri, Alicia Rovó, Bipin N. Savani, Mary Lynn Savoie, Sachiko Seo, Melhem Solh, Celalettin Ustun, Leo F. Verdonck, John R. Wingard, Baldeep Wirk, Nelli Bejanyan, Richard J. Jones, Taiga Nishihori, Betul Oran, Ryotaro Nakamura, Bart Scott, Wael Saber, and Vikas Gupta

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Therapy for Stage IV Non-Small Cell Lung Cancer With Driver Alterations: ASCO Living Guideline, Version 2023.3, Ishmael A. Jaiyesimi, Natasha B. Leighl, Nofisat Ismaila, Krishna Alluri, Narjust Florez, Shirish M. Gadgeel, Gregory Masters, Erin L. Schenk, Bryan J. Schneider, Lecia Sequist, Navneet Singh, Lyudmila Bazhenova, Elizabeth Blanchard, Janet Freeman-Daily, Naoki Furuya, Balazs Halmos, Ibrahim Hanna Azar, Sara Kuruvilla, Michael Mullane, Jarushka Naidoo, Joshua E. Reuss, David R. Spigel, Dwight H. Owen, and Jyoti D. Patel

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Therapy for Stage IV Non-Small Cell Lung Cancer Without Driver Alterations: ASCO Living Guideline, Version 2023.3, Ishmael A. Jaiyesimi, Natasha B. Leighl, Nofisat Ismaila, Krishna Alluri, Narjust Florez, Shirish M. Gadgeel, Gregory Masters, Erin L. Schenk, Bryan J. Schneider, Lecia Sequist, Navneet Singh, Lyudmila Bazhenova, Elizabeth Blanchard, Janet Freeman-Daily, Naoki Furuya, Balazs Halmos, Ibrahim Hanna Azar, Sara Kuruvilla, Michael Mullane, Jarushka Naidoo, Joshua E. Reuss, David R. Spigel, Dwight H. Owen, and Jyoti D. Patel

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Trial Design and Optimal Determination of CNS Activity of Small Molecule Targeted Therapy in NSCLC, Elaine M. Jennings, D. Ross Camidge, Shirish M. Gadgeel, and Scott Barker

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Sezary Syndrome: A Case Report and Review of Current Therapeutics, Jayasree Krishnan and Kannan Thanikachalam

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Brief Report: Impact of Anti-Cancer Treatments on Outcomes of COVID-19 in Patients With Thoracic Cancers: A CCC19 Registry Analysis, Amit A. Kulkarni, Cassandra Hennessy, Grace Wilson, Vidhyalakshmi Ramesh, Clara Hwang, Joy Awosika, Ziad Bakouny, Hina Khan, Diana Vilar-Compte, Rana McKay, Chinmay Jani, Lisa Weissmann, Elizabeth Griffiths, Gerald Batist, Nathaniel Bouganim, Blanche Mavromatis, Babar Bashir, Ryan H Nguyen, Jonathan W Riess, Matthew Puc, Anup Kasi, Stephanie Berg, Dan Ran Castillo, Brandon Hayes-Lattin, Wylie Hosmer, Daniel Flora, Sanjay Mishra, Benjamin French, Jeremy L. Warner, Gilberto Lopes, Solange Peters, and Narjust Florez

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Neoantigens and cancer-testis antigens as promising vaccine candidates for triple-negative breast cancer: Delivery strategies and clinical trials, RamaRao Malla, Mundla Srilatha, Veda Muppala, Batoul Farran, Virander Singh Chauhan, and Ganji Purnachandra Nagaraju

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Selective Personalized RadioImmunotherapy for Locally Advanced Non-Small-Cell Lung Cancer Trial (SPRINT), Nitin Ohri, Shruti Jolly, Benjamin T. Cooper, Rafi Kabarriti, William R. Bodner, Jonathan Klein, Chandan Guha, Shankar Viswanathan, Elaine Shum, Joshua K. Sabari, Haiying Cheng, Rasim A. Gucalp, Enrico Castellucci, Angel Qin, Shirish M. Gadgeel, and Balazs Halmos

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Repeat Next-Generation Sequencing Testing on Progression in Men With Metastatic Prostate Cancer Can Identify New Actionable Alterations, Joseph J. Park, Alec Chu, Jinju Li, Alicia Ali, Rana R. McKay, Clara Hwang, Matthew K. Labriola, Albert Jang, Deepak Kilari, George Mo, Deepak Ravindranathan, Laura S. Graham, Alexandra Sokolova, Abhishek Tripathi, Amanda Pilling, Tanya Jindal, Aditya Ravindra, Frank C. Cackowski, Patrick L. Sweeney, Bicky Thapa, Taylor S. Amery, Elisabeth I. Heath, Rohan Garje, Yousef Zakharia, Vadim S. Koshkin, Mehmet A. Bilen, Michael T. Schweizer, Pedro C. Barata, Tanya B. Dorff, Marcin Cieslik, Ajjai S. Alva, and Andrew J. Armstrong

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Phase 1/2 study of monalizumab plus durvalumab in patients with advanced solid tumors, Sandip P. Patel, Teresa Alonso-Gordoa, Susana Banerjee, Ding Wang, Jarushka Naidoo, Nathan E. Standifer, Doug C. Palmer, Lin-Yang Cheng, Panagiotis Kourtesis, Maria L. Ascierto, Mayukh Das, Jennifer R. Diamond, Matthew D. Hellmann, and Benedito A. Carneiro

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Herbal and Non-Herbal Dietary Supplements for Psychiatric Indications: Considerations in Liver Transplantation, Shivali Patel, Kinza Tareen, Chandni Patel, and Amy Rosinski

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Entrectinib in ROS1-positive advanced non-small cell lung cancer: the phase 2/3 BFAST trial, Solange Peters, Shirish M. Gadgeel, Tony Mok, Ernest Nadal, Saadettin Kilickap, Aurélie Swalduz, Jacques Cadranel, Shunichi Sugawara, Chao-Hua Chiu, Chong-Jen Yu, Mor Moskovitz, Tomohiro Tanaka, Rhea Nersesian, Sarah M. Shagan, Margaret Maclennan, Michael Mathisen, Vijay Bhagawati-Prasad, Cheick Diarra, Zoe June Assaf, Venice Archer, and Rafal Dziadziuszko

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A Phase II Trial of Pevonedistat and Docetaxel in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer, Angel Qin, Leah Wells, Binu Malhotra, Shirish M. Gadgeel, Bryan J. Schneider, Nithya Ramnath, John D. Rice, and Gregory P. Kalemkerian

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Observational cohort study of long-term outcomes of liver transplantation in haemophilia, Margaret V. Ragni, Jessica Callis, Nabil Daoud, Brian Hu, Matthew Manuel, Jarren Santos, Jonathan Schwartz, Kenneth D. Friedman, Peter Kouides, Philip Kuriakose, Andrew D. Leavitt, Ming Y. Lim, Nicoletta Machin, Michael Recht, and Tammuella Chrisentery-Singleton

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At the Speed of SOUND: The Pace of Change for Axillary Management in Breast Cancer, Theresa Schwartz

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Axillary nodal staging in breast cancer: what have we learned?, Theresa L. Schwartz

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Deciphering cellular plasticity in pancreatic cancer for effective treatments, Md Hafiz Uddin, Dingqiang Zhang, Irfana Muqbil, Bassel F. El-Rayes, Herbert Chen, Philip A. Philip, and Asfar S. Azmi

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Intratumoral Cell Neighborhoods Coordinate Outcomes in Pancreatic Ductal Adenocarcinoma, Max M. Wattenberg, Sarah Colby, Ignacio Garrido-Laguna, Yuqing Xue, Renee Chang, Devora Delman, Jesse Lee, Kajsa Affolter, Sean J. Mulvihill, M. Shaalan Beg, Andrea Wang-Gillam, James Lloyd Wade, Katherine A. Guthrie, E. Gabriela Chiorean, Syed A. Ahmad, Andrew M. Lowy, Philip A. Philip, Davendra P. S Sohal, and Gregory L. Beatty

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A next-generation BRAF inhibitor overcomes resistance to BRAF inhibition in patients with BRAF-mutant cancers using pharmacokinetics-informed dose escalation, Rona Yaeger, Meredith A. McKean, Rizwan Haq, J. Thaddeus Beck, Matthew H. Taylor, Jonathan Eliezer Cohen, Daniel W. Bowles, Shirish M. Gadgeel, Catalin Mihalcioiu, Kyriakos P. Papadopoulos, Eli L. Diamond, Keren B. Sturtz, Gang Feng, Stefanie K. Drescher, Micaela B. Reddy, Bhaswati Sengupta, Arnab K. Maity, Suzy A. Brown, Anurag Singh, Eric N. Brown, Brian R. Baer, Jim Wong, Tung-Chung Mou, Wen-I Wu, Dean R. Kahn, Sunyana Gadal, Neal Rosen, John J. Gaudino, Patrice A. Lee, Dylan P. Hartley, and S. Michael Rothenberg

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Notch Signaling Regulates Immunosuppressive Tumor-Associated Macrophage Function in Pancreatic Cancer, Wei Yan, Rosa E. Menjivar, Monica E. Bonilla, Nina G. Steele, Samantha B. Kemp, Wenting Du, Katelyn L. Donahue, Kristee L. Brown, Eileen S. Carpenter, Faith R. Avritt, Valerie M. Irizarry-Negron, Sion Yang, William R. Burns, Yaqing Zhang, Marina Pasca di Magliano, and Filip Bednar

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Clinical implications of AR alterations in advanced prostate cancer: a multi-institutional collaboration, Zeynep B. Zengin, Nicholas C. Henderson, Joseph J. Park, Alicia Ali, Charles Nguyen, Clara Hwang, Pedro C. Barata, Mehmet A. Bilen, Laura Graham, George Mo, Deepak Kilari, Abhishek Tripathi, Matthew Labriola, Shoshana Rothstein, Rohan Garje, Vadim S. Koshkin, Vaibhav G. Patel, Michael T. Schweizer, Andrew J. Armstrong, Rana R. McKay, Ajjai Alva, and Tanya Dorff

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Altered histone acetylation patterns in pancreatic cancer cell lines induce subtype‑specific transcriptomic and phenotypical changes, Quan Zhou, Svenja Pichlmeier, Anna Maria Denz, Nicole Schreiner, Tobias Straub, Simone Benitz, Julia Wolff, Lisa Fahr, Maria Del Socorro Escobar Lopez, Jörg Kleeff, Julia Mayerle, Ujjwal Mukund Mahajan, and Ivonne Regel

Submissions from 2023

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Outcomes of Patients with Thrombocytopenia Evaluated at Hematology Subspecialty Clinics, Zaid H. Abdel Rahman, Kevin C. Miller, Hiba Jabbour, Yaser Alkhatib, and Vijayalakshmi Donthireddy

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Brief Report: Prognostic Relevance of 3q Amplification in Squamous Cell Carcinoma of the Lung, Fawzi Abu Rous, Pin Li, Shannon Carskadon, Sunny R. K Singh, Rebecca Chacko, Hassan Abushukair, Shirish M. Gadgeel, and Nallasivam Palanisamy

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Challenges Faced by J-1 International Medical Graduates (IMGs) During COVID-19 Pandemic, Fawzi Abu Rous and Ivy Riano

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Clinicopathologic characteristics of early-onset breast cancer: a comparative analysis of cases from across Ghana, Patrick Kafui Akakpo, Emmanuel Gustav Imbeah, Lawrence Edusei, Simon Naporo, Kofi Ulzen-Appiah, Joe Nat Clegg-Lamptey, Florence Dedey, Josephine Nsaful, Nelson Affram, Beatrice Wiafe, Samuel Mensah, Michael Nortey, Mohammed Sheriff, Forster Amponsah-Manu, Kwabena Agbedinu, and Evelyn M. Jiagge

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Phase II trial of nivolumab and metformin in patients with treatment-refractory microsatellite stable metastatic colorectal cancer, Mehmet Akce, Batoul Farran, Jeffrey M. Switchenko, Manali Rupji, Sandra Kang, Lana Khalil, Amanda Ruggieri-Joyce, Brian Olson, Walid L. Shaib, Christina Wu, Olatunji B. Alese, Maria Diab, Gregory B. Lesinski, and Bassel F. El-Rayes

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A Rare Presentation of Concomitant Lung Disease and Hepatitis After Rituximab Treatment: A Case Report, Linda Albusoul, Hussna Abunafessa, and Vrushali Dabak

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Lifestyle Modifications and Nutritional and Therapeutic Interventions in Delaying the Progression of Chronic Kidney Disease: A Review, Lean Alkhatib, Lorena A. Velez Diaz, Samyukta Varma, Arsh Chowdhary, Prachi Bapat, Hai Pan, Geetika Kukreja, Prasannalaxmi Palabindela, Sri Abirami Selvam, and Kartik Kalra

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Clinical Outcome in Patients With Early-Stage Small Cell Lung Cancer Treated With Surgery or Radiation in the Absence of Prophylactic Cranial Irradiation: A Single-Center Retrospective Study, Sondos Al Khatib, Khaled Adil, Lonni Schultz, Shirish M. Gadgeel, Andrew Popoff, Munther Ajlouni, Michael Simoff, Benjamin Movsas, and Aharon Feldman

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Persistent Peri-Ablation Blood-Brain Barrier Opening After Laser Interstitial Thermal Therapy for Brain Tumors., Seamus Bartlett, Tavarekere N. Nagaraja, Brent Griffith, Katelynn G. Farmer, Meredith Van Harn, Sameah A. Haider, Rachel J. Hunt, Glauber Cabral, Robert A. Knight, Olivia G. Valadie, Stephen L. Brown, James R. Ewing, and Ian Y. Lee

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Phase I Study of Single-Agent Anti-Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates, Julie R. Brahmer, Charles G. Drake, Ira Wollner, John D. Powderly, Joel Picus, William H. Sharfman, Elizabeth Stankevich, Alice Pons, Theresa M. Salay, Tracee L. McMiller, Marta M. Gilson, Changyu Wang, Mark Selby, Janis M. Taube, Robert Anders, Lieping Chen, Alan J. Korman, Drew M. Pardoll, Israel Lowy, and Suzanne L. Topalian

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Clinical implications of Wnt signaling alterations in patients (pts) with advanced prostate cancer (aPC), Amanda Broderick, Jinju Li, Alec Chu, Clara Hwang, Pedro C. Barata, Frank C. Cackowski, Matthew Labriola, Alyssa Ghose, Mehmet A. Bilen, Deepak Kilari, Laura Graham, Abhishek Tripathi, Rohan Garje, Vadim S. Koshkin, Elizabeth Pan, Tanya B. Dorff, Rana R. McKay, Michael T. Schweizer, Ajjai S. Alva, and Andrew J. Armstrong

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A First-in-human, Dose-escalation Study of the Methionine Aminopeptidase 2 Inhibitor M8891 in Patients with Advanced Solid Tumors, Michael A. Carducci, Ding Wang, Christina Habermehl, Matthias Bödding, Felix Rohdich, Floriane Lignet, Klaus Duecker, Oleksandr Karpenko, Linda Pudelko, Claude Gimmi, and Patricia LoRusso

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KRT17High/CXCL8+ tumor cells display both classical and basal features and regulate myeloid infiltration in the pancreatic cancer microenvironment, Eileen S Carpenter, Padma Kadiyala, Ahmed M Elhossiny, Samantha B Kemp, Jay Li, Nina G. Steele, Rémy Nicolle, Zeribe C Nwosu, Julia Freeman, Henry Dai, Daniel Paglia, Wenting Du, Katelyn Donahue, Jacqueline Morales, Paola I Medina-Cabrera, Monica E Bonilla, Lindsey Harris, Stephanie The, Valerie Gunchick, Nicole Peterson, Kristee Brown, Michael Mattea, Carlos E Espinoza, Jake McGue, Sarah M Kabala, Rachel K Baliira, Nur M Renollet, Ayden G Mooney, Jianhua Liu, Sean Bhalla, Jeremy P Farida, Christopher Ko, Jorge D Machicado, Richard S Kwon, Erik-Jan Wamsteker, Allison Schulman, Michelle A Anderson, Ryan Law, Anoop Prabhu, Pierre A Coulombe, Arvind Rao, Timothy L Frankel, Filip Bednar, Jiaqi Shi, Vaibhav Sahai, and Marina Pasca di Magliano

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Breakthrough SARS-CoV-2 infections among patients with cancer following two and three doses of COVID-19 mRNA vaccines: a retrospective observational study from the COVID-19 and Cancer Consortium, Toni K. Choueiri, Chris Labaki, Ziad Bakouny, Chih-Yuan Hsu, Andrew L. Schmidt, Gilberto de Lima Lopes, Clara Hwang, Sunny R. K Singh, Chinmay Jani, Lisa B. Weissmann, Elizabeth A. Griffiths, Susan Halabi, Ulysses Wu, Stephanie Berg, Timothy E. O'Connor, Trisha M. Wise-Draper, Orestis A. Panagiotou, Elizabeth J. Klein, Monika Joshi, Fares Yared, Miriam Santos Dutra, Na Tosha N. Gatson, Sibel Blau, Harpreet Singh, Rahul Nanchal, Rana R. McKay, Taylor K. Nonato, Ryann Quinn, Samuel M. Rubinstein, Matthew Puc, Blanche H. Mavromatis, Praveen Vikas, Bryan Faller, Howard A. Zaren, Salvatore Del Prete, Karen Russell, Daniel Y. Reuben, Melissa K. Accordino, Harpreet Singh, Christopher R. Friese, Sanjay Mishra, Donna R. Rivera, Yu Shyr, Dimitrios Farmakiotis, and Jeremy L. Warner

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Lorazepam Stimulates IL6 Production and Is Associated with Poor Survival Outcomes in Pancreatic Cancer, Abigail C. Cornwell, Arwen A. Tisdale, Swati Venkat, Kathryn E. Maraszek, Abdulrahman A. Alahmari, Anthony George, Kristopher Attwood, Madison George, Donald Rempinski, Janusz Franco-Barraza, Mukund Seshadri, Mark D. Parker, Eduardo Cortes Gomez, Christos Fountzilas, Edna Cukierman, Nina G. Steele, and Michael E. Feigin

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Images in Immunotherapy and Precision Oncology: Angiosarcoma of the Spleen and Liver, Anagha Deshpande, Javier Munoz, Katalin Kelemen, Vrushali Dabak, Amr Hanbali, and Razelle Kurzrock

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Clinical implications of AR alterations in advanced prostate cancer: A multi-institutional collaboration, Tanya Dorff, Zeynep Zengin, Nicholas Henderson, Alicia Ali, Charles Nguyen, Clara Hwang, Pedro C Barata, Mehmet Bilen, Laura Graham, George Mo, Deepak Kilari, Abhishek Tripathi, Matthew Labriola, Shoshana Rothstein, Rohan Garje, Vadim Koshkin, Vaibhav Patel, Michael Schweizer, Andrew Armstrong, Rana McKay, and Ajjai Alva

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SHP2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors to Re-treatment with Targeted Therapy, Alexander Drilon, Manish R. Sharma, Melissa L. Johnson, Timothy A. Yap, Shirish M. Gadgeel, Dale Nepert, Gang Feng, Micaela B. Reddy, Allison S. Harney, Mohamed Elsayed, Adam W. Cook, Christina E. Wong, Ronald J. Hinklin, Yutong Jiang, Eric N. Brown, Nickolas A. Neitzel, Ellen R. Laird, Wen-I Wu, Anurag Singh, Ping Wei, Keith A. Ching, John J. Gaudino, Patrice A. Lee, Dylan P. Hartley, and S. Michael Rothenberg

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The management of hepatocellular carcinoma. Current expert opinion and recommendations derived from the 24th ESMO/World Congress on Gastrointestinal Cancer, Barcelona, 2022, Michel Ducreux, Ghassan K. Abou-Alfa, Tanios S. Bekaii-Saab, Jordan D. Berlin, Andrés Cervantes, Thierry de Baere, Cathy Eng, Peter Galle, Sharlene Gill, Thomas Gruenberger, Karin Haustermans, Angela Lamarca, Pierre Laurent-Puig, Josep M. Llovet, Florian Lordick, Teresa Macarulla, Deborah Mukherji, Kei Muro, Radka Obermannova, Juan Manuel O'Connor, Eileen O'Reilly, Pia Österlund, Philip A. Philip, Gerald Prager, Erika Ruiz-Garcia, Bruno Sangro, Thomas Seufferlein, Josep Tabernero, Chris Verslype, Harpreet Wasan, and Eric Van Cutsem

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Neuropsychiatric disorders in adults undergoing chimeric antigen receptor T cells therapy for aggressive lymphomas and acute lymphoblastic leukemia, Josephine Emole, Odunayo Lawal, Oleksandra Lupak, Hemalatha Rangarajan, and Itoro Udo

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Graft-versus-host disease: teaching old drugs new tricks at less cost, Shatha Farhan and Shernan G. Holtan

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Survival Outcomes in Women with Unilateral, Triple-Negative, Breast Cancer Correlated with Contralateral Prophylactic Mastectomy, Genevieve A. Fasano, Solange Bayard, Yalei Chen, Jennifer Marti, Rache Simmons, Alexander Swistel, Jessica Bensenhaver, Melissa Davis, and Lisa Newman

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Phase II study of docetaxel and trametinib in patients with KRAS mutation positive recurrent non-small cell lung cancer (NSCLC) (SWOG S1507, NCT-02642042), Shirish M. Gadgeel, Jieling Miao, Jonathan W. Riess, James Moon, Philip C. Mack, Gregory J. Gerstner, Timothy F. Burns, Asma Taj, Wallace L. Akerley, Konstantin H. Dragnev, Noel Laudi, Mary W. Redman, Jhanelle E. Gray, David R. Gandara, and Karen Kelly

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Associations of Tissue Tumor Mutational Burden and Mutational Status With Clinical Outcomes With Pembrolizumab Plus Chemotherapy Versus Chemotherapy For Metastatic NSCLC, Marina C. Garassino, Shirish M. Gadgeel, Silvia Novello, Balazs Halmos, Enriqueta Felip, Giovanna Speranza, Rina Hui, Edward B. Garon, Hidehito Horinouchi, Shunichi Sugawara, Delvys Rodriguez-Abreu, Martin Reck, Razvan Cristescu, Deepti Aurora-Garg, Andrey Loboda, Jared Lunceford, Julie Kobie, Mark Ayers, Bilal Piperdi, M. Catherine Pietanza, and Luis Paz-Ares

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Pembrolizumab Plus Pemetrexed and Platinum in Nonsquamous Non-Small-Cell Lung Cancer: 5-Year Outcomes From the Phase 3 KEYNOTE-189 Study, Marina C. Garassino, Shirish M. Gadgeel, Giovanna Speranza, Enriqueta Felip, Emilio Esteban, Manuel Dómine, Maximilian J. Hochmair, Steven F. Powell, Helge G. Bischoff, Nir Peled, Francesco Grossi, Ross R. Jennens, Martin Reck, Rina Hui, Edward B. Garon, Takayasu Kurata, Jhanelle E. Gray, Paul Schwarzenberger, Erin Jensen, M. Catherine Pietanza, and Delvys Rodríguez-Abreu

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A Case of Right Ventricular Failure Secondary to Acute Chest Syndrome Managed With Early Red Cell Exchange Transfusion, Abeselom Geletu, Josephine Emole, Alaa Abu Sayf, Oscar A. Hinojosa, and Alexandra Gastesi

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Carcinoma En Cuirasse: A Rare but Striking Cutaneous Manifestation of Metastatic Breast Cancer, Manasi Godbole, Kashmira Wani, Shereen Q. Zia, and Vrushali Dabak

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Sepsis-related outcomes of patients with Philadelphia-negative myeloproliferative neoplasms, Luis F. Gonzalez Mosquera, Bernard Moscoso, Pool Tobar, Diana Cardenas-Maldonado, Alida I. Podrumar, Ruben Mesa, and John A. Cuenca

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Sepsis-Related Outcomes of Patients with Philadelphia-Negative Myeloproliferative Neoplasms, Luis F. Gonzalez Mosquera, Bernard Moscoso, Pool Tobar, Diana Cardenas-Maldonado, Alida I. Podrumar, Ruben Mesa, and John A. Cuenca

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Systemic Anticancer Therapy and Thromboembolic Outcomes in Hospitalized Patients With Cancer and COVID-19, Shuchi Gulati, Chih-Yuan Hsu, Surbhi Shah, Pankil K Shah, Rebecca Zon, Susan Alsamarai, Joy Awosika, Ziad El-Bakouny, Babar Bashir, Alicia Beeghly, Stephanie Berg, Daniel de-la-Rosa-Martinez, Deborah B. Doroshow, Pamela C. Egan, Joshua Fein, Daniel B. Flora, Christopher R. Friese, Ariel Fromowitz, Elizabeth A. Griffiths, Clara Hwang, Chinmay Jani, Monika Joshi, Hina Khan, Elizabeth J. Klein, Natalie Knox Heater, Vadim S. Koshkin, Daniel H. Kwon, Chris Labaki, Tahir Latif, Rana R. McKay, Gayathri Nagaraj, Elizabeth S. Nakasone, Taylor Nonato, Hyma V. Polimera, Matthew Puc, Pedram Razavi, Erika Ruiz-Garcia, Renee Maria Saliby, Aditi Shastri, Sunny R. K Singh, Vicky Tagalakis, Diana Vilar-Compte, Lisa B. Weissmann, Cy R. Wilkins, Trisha M. Wise-Draper, Michael T. Wotman, James J. Yoon, Sanjay Mishra, Petros Grivas, Yu Shyr, Jeremy L. Warner, Jean M. Connors, Dimpy P. Shah, and Rachel P. Rosovsky

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MRTX-500 Phase 2 Trial: Sitravatinib With Nivolumab in Patients With Non-Squamous Non-Small Cell Lung Cancer Progressing On/After Checkpoint Inhibitor Therapy or Chemotherapy, Kai He, David Berz, Shirish M. Gadgeel, Wade T. Iams, Debora S. Bruno, Collin M. Blakely, Alexander I. Spira, Manish R. Patel, David M. Waterhouse, Donald A. Richards, Anthony Pham, Robert Jotte, David S. Hong, Edward B. Garon, Anne Traynor, Peter Olson, Lisa Latven, Xiaohong Yan, Ronald Shazer, and Ticiana A. Leal

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Cancer is chronic but antimicrobial stewardship is iconic: A retrospective cohort of optimal antibiotic use in ambulatory oncology clinics, Tiffany A. Ho, Katelyn M. Patterson, Shirish M. Gadgeel, Rachel M. Kenney, and Michael P. Veve

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A Bitter Taste Receptor as a Novel Molecular Target on Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma, Jessica Hung, Samantha M. Perez, Siva Sai Krishna Dasa, Sarah P. Hall, Danielle B. Heckert, Brian P. Murphy, Howard C. Crawford, Kimberly A. Kelly, and Lindsey T. Brinton

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Biomarker-Directed Therapy in Black and White Men With Metastatic Castration-Resistant Prostate Cancer, Clara Hwang, Nicholas C. Henderson, Shih-Chun Chu, Brandon Holland, Frank C. Cackowski, Amanda B. Pilling, Albert Jang, Shoshana Rothstein, Matthew Labriola, Joseph J. Park, Alyssa Ghose, Mehmet A. Bilen, Seema Mustafa, Deepak Kilari, Michael J. Pierro, Bicky Thapa, Abhishek Tripathi, Rohan Garje, Aditya Ravindra, Vadim S. Koshkin, Erik Hernandez, Michael T. Schweizer, Andrew J. Armstrong, Rana R. McKay, Tanya B. Dorff, Ajjai S. Alva, and Pedro C. Barata

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Brief Report on Use of Pembrolizumab With or Without Chemotherapy for Advanced Lung Cancer: A Real-World Analysis, Monika A. Izano, Connor Sweetnam, Chenan Zhang, James L. Weese, Douglas Reding, Jonathan Treisman, Anand Patel, Bindu Potugari, Andrew Stafford, Frank M. Wolf, Mary Tran, Thomas D. Brown, and Shirish M. Gadgeel

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Tumor sequencing of African ancestry reveals differences in clinically relevant alterations across common cancers, Evelyn M. Jiagge, Dexter X Jin, Justin Y Newberg, Tomin Perea-Chamblee, Kelly R Pekala, Christopher Fong, Michele Waters, David Ma, Yvonne Dei-Adomakoh, Gilles Erb, Kanika S Arora, Sophia L Maund, Njoki Njiraini, Atara Ntekim, Susie Kim, Xuechun Bai, Marlene Thomas, Ronwyn van Eeden, Priti Hegde, Justin Jee, Debyani Chakravarty, Nikolaus Schultz, Michael F Berger, Garrett M Frampton, Ethan S Sokol, and Jian Carrot-Zhang

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Impact of COVID-19 in patients on active melanoma therapy and with history of melanoma, Douglas B. Johnson, Michael B. Atkins, Cassandra Hennessy, Trisha Wise-Draper, Hannah Heilman, Joy Awosika, Ziad Bakouny, Chris Labaki, Renee Maria Saliby, Clara Hwang, Sunny R. K Singh, Nino Balanchivadze, Christopher R. Friese, Leslie A. Fecher, James J. Yoon, Brandon Hayes-Lattin, Mehmet A. Bilen, Cecilia A. Castellano, Gary H. Lyman, Lisa Tachiki, Sumit A. Shah, Michael J. Glover, Daniel B. Flora, Elizabeth Wulff-Burchfield, Anup Kasi, Saqib H. Abbasi, Dimitrios Farmakiotis, Kendra Viera, Elizabeth J. Klein, Lisa B. Weissman, Chinmay Jani, Matthew Puc, Catherine C. Fahey, Daniel Y. Reuben, Sanjay Mishra, Alicia Beeghly-Fadiel, Benjamin French, and Jeremy L. Warner

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Targeting Cellular Metabolism With CPI-613 Sensitizes Pancreatic Cancer Cells to Radiation Therapy, Husain Yar Khan, Mandana Kamgar, Amro Aboukameel, Sahar Bannoura, Brian Y. Chung, Yiwei Li, Mohammed Najeeb Al Hallak, Philip A. Philip, Susan Tsai, Sanjeev Luther, William A. Hall, and Asfar S. Azmi

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Race-Associated Genomic Correlates of Therapeutic Response in African American Patients With Non-Small-Cell Lung Cancer, Pin Li, Kaitlyn Kane, Frank M. Wolf, Anna B. Berry, Shirish M. Gadgeel, and Amanda B. Pilling

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Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies, Xihao Li, Corbin Quick, Hufeng Zhou, Sheila M Gaynor, Yaowu Liu, Han Chen, Margaret Sunitha Selvaraj, Ryan Sun, Rounak Dey, Donna K Arnett, Lawrence F Bielak, Joshua C Bis, John Blangero, Eric Boerwinkle, Donald W Bowden, Jennifer A Brody, Brian E Cade, Adolfo Correa, L Adrienne Cupples, Joanne E Curran, Paul S de Vries, Ravindranath Duggirala, Barry I Freedman, Harald H H Göring, Xiuqing Guo, Jeffrey Haessler, Rita R Kalyani, Charles Kooperberg, Brian G Kral, Leslie A Lange, Ani Manichaikul, Lisa W Martin, Stephen T McGarvey, Braxton D Mitchell, May E Montasser, Alanna C Morrison, Take Naseri, Jeffrey R O'Connell, Nicholette D Palmer, Patricia A Peyser, Bruce M Psaty, Laura M Raffield, Susan Redline, Alexander P Reiner, Muagututi'a Sefuiva Reupena, Kenneth M Rice, Stephen S Rich, Colleen M Sitlani, Jennifer A Smith, Kent D Taylor, Ramachandran S Vasan, Cristen J Willer, James G Wilson, Lisa R Yanek, Wei Zhao, Jerome I Rotter, Pradeep Natarajan, Gina M Peloso, Zilin Li, and Xihong Lin

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KMT2D links TGF-β signaling to noncanonical activin pathway and regulates pancreatic cancer cell plasticity, Shuang Lu, Hong Sun Kim, Yubo Cao, Karan Bedi, Lili Zhao, Ishwarya Venkata Narayanan, Brian Magnuson, Yumei Gu, Jing Yang, Zhujun Yi, Sepideh Babaniamansour, Sargis Shameon, Chang Xu, Michelle T. Paulsen, Ping Qiu, Sivakumar Jeyarajan, Mats Ljungman, Dafydd Thomas, Yali Dou, Howard C. Crawford, Marina Pasca di Magliano, Kai Ge, Bo Yang, and Jiaqi Shi

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Arginase 1 is a key driver of immune suppression in pancreatic cancer, Rosa Elena Menjivar, Zeribe C. Nwosu, Wenting Du, Katelyn L. Donahue, Hanna S. Hong, Carlos Espinoza, Kristee Brown, Ashley Velez-Delgado, Wei Yan, Fatima Lima, Allison Bischoff, Padma Kadiyala, Daniel Salas-Escabillas, Howard C. Crawford, Filip Bednar, Eileen Carpenter, Yaqing Zhang, Christopher J. Halbrook, Costas A. Lyssiotis, and Marina Pasca di Magliano

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COVID-19 severity and cardiovascular outcomes in SARS-CoV-2-infected patients with cancer and cardiovascular disease, Melissa Y. Y Moey, Cassandra Hennessy, Benjamin French, Jeremy L. Warner, Matthew D. Tucker, Daniel J. Hausrath, Dimpy P. Shah, Jeanne M. DeCara, Ziad Bakouny, Chris Labaki, Toni K. Choueiri, Susan Dent, Nausheen Akhter, Roohi Ismail-Khan, Lisa Tachiki, David Slosky, Tamar S. Polonsky, Joy A. Awosika, Audrey Crago, Trisha Wise-Draper, Nino Balanchivadze, Clara Hwang, Leslie A. Fecher, Cyndi Gonzalez Gomez, Brandon Hayes-Lattin, Michael J. Glover, Sumit A. Shah, Dharmesh Gopalakrishnan, Elizabeth A. Griffiths, Daniel H. Kwon, Vadim S. Koshkin, Sana Mahmood, Babar Bashir, Taylor Nonato, Pedram Razavi, Rana R. McKay, Gayathri Nagaraj, Eric Oligino, Matthew Puc, Polina Tregubenko, Elizabeth M. Wulff-Burchfield, Zhuoer Xie, Thorvardur R. Halfdanarson, Dimitrios Farmakiotis, Elizabeth J. Klein, Elizabeth V. Robilotti, Gregory J. Riely, Jean-Bernard Durand, Salim S. Hayek, Lavanya Kondapalli, Stephanie Berg, Timothy E. O'Connor, Mehmet A. Bilen, Cecilia Castellano, Melissa K. Accordino, Blau Sibel, Lisa B. Weissmann, Chinmay Jani, Daniel B. Flora, Lawrence Rudski, Miriam Santos Dutra, Bouganim Nathaniel, Erika Ruíz-García, Diana Vilar-Compte, Shilpa Gupta, Alicia Morgans, and Anju Nohria

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Daclatasvir, an Antiviral Drug, Downregulates Tribbles 2 Pseudokinase and Resensitizes Enzalutamide-Resistant Prostate Cancer Cells, Jitender Monga, Frederick A. Valeriote, Clara Hwang, Shirish M. Gadgeel, and Jagadananda Ghosh

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Association between the choice of the conditioning regimen and outcomes of allogeneic hematopoietic cell transplantation for myelofibrosis, Guru Subramanian Guru Murthy, Soyoung Kim, Noel Estrada-Merly, Muhammad Bilal Abid, Mahmoud Aljurf, Amer Assal, Talha Badar, Sherif M. Badawy, Karen Ballen, Amer Beitinjaneh, Jan Cerny, Saurabh Chhabra, Zachariah DeFilipp, Bhagirathbhai Dholaria, Miguel Angel Diaz Perez, Shatha Farhan, Cesar O. Freytes, Robert Peter Gale, Siddhartha Ganguly, Vikas Gupta, Michael R. Grunwald, Nada Hamad, Gerhard C. Hildebrandt, Yoshihiro Inamoto, Tania Jain, Omer Jamy, Mark Juckett, Matt Kalaycio, Maxwell M. Krem, Hillard M. Lazarus, Mark Litzow, Reinhold Munker, Hemant S. Murthy, Sunita Nathan, Taiga Nishihori, Guillermo Ortí, Sagar S. Patel, Marjolein Van der Poel, David A. Rizzieri, Bipin N. Savani, Sachiko Seo, Melhem Solh, Leo F. Verdonck, Baldeep Wirk, Jean A. Yared, Ryotaro Nakamura, Betul Oran, Bart Scott, and Wael Saber

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Clinical characteristics, racial inequities, and outcomes in patients with breast cancer and COVID-19: A COVID-19 and cancer consortium (CCC19) cohort study, Gayathri Nagaraj, Shaveta Vinayak, Ali Raza Khaki, Tianyi Sun, Nicole M Kuderer, David M Aboulafia, Jared D Acoba, Joy Awosika, Ziad Bakouny, Nicole B Balmaceda, Ting Bao, Babar Bashir, Stephanie Berg, Mehmet A Bilen, Poorva Bindal, Sibel Blau, Brianne E Bodin, Hala T Borno, Cecilia Castellano, Horyun Choi, John Deeken, Aakash Desai, Natasha Edwin, Lawrence E Feldman, Daniel B Flora, Christopher R Friese, Matthew D Galsky, Cyndi J Gonzalez, Petros Grivas, Shilpa Gupta, Marcy Haynam, Hannah Heilman, Dawn L Hershman, Clara Hwang, Chinmay Jani, Sachin R Jhawar, Monika Joshi, Virginia Kaklamani, Elizabeth J Klein, Natalie Knox, Vadim S Koshkin, Amit A Kulkarni, Daniel H Kwon, Chris Labaki, Philip E Lammers, Kate I Lathrop, Mark A Lewis, Xuanyi Li, Gilbert de Lima Lopes, Gary H Lyman, Della F Makower, Abdul-Hai Mansoor, Merry-Jennifer Markham, Sandeep H Mashru, Rana R McKay, Ian Messing, Vasil Mico, Rajani Nadkarni, Swathi Namburi, Ryan H Nguyen, Taylor Kristian Nonato, Tracey Lynn O'Connor, Orestis A Panagiotou, Kyu Park, Jaymin M Patel, Kanishka GopikaBimal Patel, Jeffrey Peppercorn, Hyma Polimera, Matthew Puc, Yuan James Rao, Pedram Razavi, Sonya A Reid, Jonathan W Riess, Donna R Rivera, Mark Robson, Suzanne J Rose, Atlantis D Russ, Lidia Schapira, Pankil K Shah, M Kelly Shanahan, Lauren C Shapiro, Melissa Smits, Daniel G Stover, Mitrianna Streckfuss, Lisa Tachiki, Michael A Thompson, Sara M Tolaney, Lisa B Weissmann, Grace Wilson, Michael T Wotman, Elizabeth M Wulff-Burchfield, Sanjay Mishra, Benjamin French, Jeremy L Warner, Maryam B Lustberg, Melissa K Accordino, and Dimpy P Shah

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Intracranial Efficacy of Adagrasib in Patients From the KRYSTAL-1 Trial With KRAS(G12C)-Mutated Non-Small-Cell Lung Cancer Who Have Untreated CNS Metastases, Marcelo V. Negrao, Alexander I. Spira, Rebecca S. Heist, Pasi A. Jänne, Jose M. Pacheco, Jared Weiss, Shirish M. Gadgeel, Karen Velastegui, Wenjing Yang, Hirak Der-Torossian, James G. Christensen, and Joshua K. Sabari

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Ibrutinib combination therapy for advanced gastrointestinal and genitourinary tumours: results from a phase 1b/2 study, Do-Youn Oh, Maria Alsina Maqueda, David I. Quinn, Peter J. O'Dwyer, Ian Chau, Sun Young Kim, Ignacio Duran, Daniel Castellano, Jordan Berlin, Begona Mellado, Stephen K. Williamson, Keun-Wook Lee, Francisca Marti, Paul Mathew, Muhammad Wasif Saif, Ding Wang, Elizabeth Chong, Jacqueline Hilger-Rolfe, James P. Dean, and Hendrik-Tobias Arkenau

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Aplastic Anemia Mimicking Myelofibrosis: A Diagnostic Dilemma, Neel Patel, Hamza Mirza, Payal Bai, Vedant Shah, Harsh Patel, Milan Khealani, Geetika Kukreja, and Sri J. Obulareddy

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Tarlatamab, a First-In-Class DLL3-Targeted Bispecific T-Cell Engager, in Recurrent Small Cell Lung Cancer: An Open-Label, Phase I Study., Luis Paz-Ares, Stephane Champiat, W. Victoria Lai, Hiroki Izumi, Ramaswamy Govindan, Michael Boyer, Horst-Dieter Hummel, Hossein Borghaei, Melissa L. Johnson, Neeltje Steeghs, Fiona Blackhall, Afshin Dowlati, Noemi Reguart, Tatsuya Yoshida, Kai He, Shirish M. Gadgeel, Enriqueta Felip, Yiran Zhang, Amrita Pati, Mukul Minocha, Sujoy Mukherjee, Amanda Goldrick, Dirk Nagorsen, Nooshin Hashemi Sadraei, and Taofeek K. Owonikoko

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Uncovering the Burden of Immune-Related Adverse Events in Immunotherapy: Insights from a Nationally Representative Sample, Rayli Pichardo, Yazan Abu Omar, Kashmira Wani, Kathren Shango, and Ding Wang

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A Rare Case of Splenic Infarct Secondary to Mobile Cardiac Echodensity, Sruthi Ramanan, Harjinder Singh, Omair Ahmed, Mark Zande, and Malcolm Trimble

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Short-term changes in ultrasound tomography measures of breast density and treatment-associated endocrine symptoms after tamoxifen therapy, Cody Ramin, Ruth M. Pfeiffer, Sharon Fan, Maeve Mullooly, Roni T. Falk, Kristine Jones, Neil E. Caporaso, Lisa Bey-Knight, Mark A. Sak, Michael S. Simon, David H. Gorski, Haythem Y. Ali, Peter Littrup, Neb Duric, Mark E. Sherman, and Gretchen L. Gierach

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Stereoselective Synthesis of Sialyl Lewis(a) Antigen and the Effective Anticancer Activity of Its Bacteriophage Qβ Conjugate as an Anticancer Vaccine, Zahra Rashidijahanabad, Sherif Ramadan, Nicholas A O'Brien, Athar Nakisa, Shuyao Lang, Howard C. Crawford, Jeffrey C Gildersleeve, and Xuefei Huang

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PP01.10 A Randomized, Open-Label Phase 2 Study of the TORC 1/2 Inhibitor Sapanisertib in Relapsed/Refractory (R/R) NFE2L2 (NRF2)-Mutated and Wild-Type (WT) Squamous Non-Small Cell Lung Cancer (sqNSCLC), J. W. Riess, M. L. Johnson, Shirish M. Gadgeel, F. Skoulidis, B. Sumrow, E. Kuriakose, K. Albert, N. Kittrell, L. Akella, G. Fiji, and P. Paik

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Pancreatic Ubap2 deletion regulates glucose tolerance, inflammation, and protection from cerulein-induced pancreatitis, Ram Vinod Roy, Nicolas Means, Geeta Rao, Sima Asfa, Venkateshwar Madka, Anindya Dey, Yushan Zhang, Monalisa Choudhury, Kar-Ming Fung, Danny N Dhanasekaran, Jacob E Friedman, Howard C. Crawford, Chinthalapally V Rao, Resham Bhattacharya, and Priyabrata Mukherjee

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Emerging Biomarkers in Immune Oncology to Guide Lung Cancer Management, Houssein Safa, Fawzi Abu Rous, Neel Belani, Hossein Borghaei, Shirish M. Gadgeel, and Balazs Halmos

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SOX17 Deficiency Mediates Pulmonary Hypertension: At the Crossroads of Sex, Metabolism, and Genetics, Shreya Sangam, Xutong Sun, Tae-Hwi Schwantes-An, Manivannan Yegambaram, Qing Lu, Yinan Shi, Todd Cook, Amanda Fisher, Andrea L. Frump, Anna Coleman, Yanan Sun, Shuxin Liang, Howard C. Crawford, Katie A. Lutz, Avinash D. Maun, Michael W. Pauciulo, Jason H. Karnes, Ketul R. Chaudhary, Duncan J. Stewart, Paul R. Langlais, Mohit Jain, Mona Alotaibi, Tim Lahm, Yan Jin, Haiwei Gu, Haiyang Tang, William C. Nichols, Stephen M. Black, and Ankit A. Desai

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Long exposure to a mixture of endocrine disruptors prediposes the ventral prostate of rats to preneoplastic lesions, Thaina Cavalleri Sousa, Letícia Pereira de Souza, Maria Luiza Silva Ricardo, Andreia Yuri Yoshigae, Karianne Delalibera Hinokuma, Ana Beatriz Ratto Gorzoni, Ariana Musa de Aquino, Wellerson Rodrigo Scarano, Anthony César de Sousa Castillho, Maria Eduarda Almeida Tavares, Alice Santos Cruz Veras, Giovana Rampazzo Teixeira, Gisele Alborghetti Nai, and Leonardo de Oliveira Mendes

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Neoadjuvant therapy for pancreatic cancer, Christoph Springfeld, Cristina R. Ferrone, Matthew H. G Katz, Philip A. Philip, Theodore S. Hong, Thilo Hackert, Markus W. Büchler, and John Neoptolemos