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Submissions from 2019

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Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents., Jehad Almaliti, Bailey Miller, Halina Pietraszkiewicz, Evgenia Glukhov, C Benjamin Naman, Toni Kline, Jeffrey Hanson, Xiaofan Li, Sihong Zhou, Frederick A Valeriote, and William H Gerwick

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Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents., Jehad Almaliti, Bailey Miller, Halina Pietraszkiewicz, Evgenia Glukhov, C Benjamin Naman, Toni Kline, Jeffrey Hanson, Xiaofan Li, Sihong Zhou, Frederick A Valeriote, and William H Gerwick

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Rates of deep molecular response by digital and conventional PCR with frontline nilotinib in newly diagnosed chronic myeloid leukemia: a landmark analysis., Jesus G Berdeja, Michael C Heinrich, Shaker R Dakhil, Stuart L Goldberg, Martha Wadleigh, Philip Kuriakose, Jorge Cortes, Jerald Radich, Bret Helton, David Rizzieri, Carole Paley, Ilva Dautaj, and Michael J Mauro

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Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp., Eduardo J E Caro-Diaz, Frederick A Valeriote, and William H Gerwick

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A Phase I/Ib Trial of the VEGFR-Sparing Multikinase RET Inhibitor RXDX-105., Alexander Drilon, Siqing Fu, Manish R Patel, Marwan Fakih, Ding Wang, Anthony J Olszanski, Daniel Morgensztern, Stephen V Liu, Byoung Chul Cho, Lyudmila Bazhenova, Cristina P Rodriguez, Robert C Doebele, Antoinette Wozniak, Karen L Reckamp, Tara Seery, Petros Nikolinakos, Zheyi Hu, Jennifer W Oliver, Denise Trone, Katherine McArthur, Rupal Patel, Pratik S Multani, and Myung-Ju Ahn

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A Noninvasive Blood-based Combinatorial Proteomic Biomarker Assay to Detect Breast Cancer in Women over age 50 with BI-RADS 3, 4, or 5 Assessment., Meredith C Henderson, Michael Silver, Quynh Tran, Elias E Letsios, Rao Mulpuri, David E Reese, Ana P Lourenco, Joshua LaBaer, Karen S Anderson, Josie Alpers, Carrie Costantini, Nitin Rohatgi, Haythem Ali, Karen Baker, Donald W Northfelt, Karthik Ghosh, Stephen R Grobmyer, Winnie Polen, and Judith K Wolf

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A Noninvasive Blood-based Combinatorial Proteomic Biomarker Assay to Detect Breast Cancer in Women over age 50 with BI-RADS 3, 4, or 5 Assessment., Meredith C Henderson, Michael Silver, Quynh Tran, Elias E Letsios, Rao Mulpuri, David E Reese, Ana P Lourenco, Joshua LaBaer, Karen S Anderson, Josie Alpers, Carrie Costantini, Nitin Rohatgi, Haythem Y Ali, Karen Baker, Donald W Northfelt, Karthik Ghosh, Stephen R Grobmyer, Winnie Polen, and Judith K Wolf

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Evaluation of a Multidisciplinary Team Approach for Generating Survivorship Care Plan Treatment Summaries in Patients With Breast Cancer., Tommy Ivanics, Erica Proctor, Yalei Chen, Haythem Y Ali, Dawn Severson, Hassan Nasser, Sonja Colbert, Laura L. Susick, Eleanor Walker, Lindsay Petersen, Jessica Bensenhaver, Randa Loutfi, S David Nathanson, and Lisa A Newman

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Atypical Chemokine Receptor 1 (DARC/ACKR1) in Breast Tumors Is Associated with Survival, Circulating Chemokines, Tumor-Infiltrating Immune Cells, and African Ancestry, Brittany D Jenkins, Rachel N Martini, Rupali Hire, Andrea Brown, Briana Bennett, I'nasia Brown, Elizabeth W Howerth, Mary Egan, Jamie Hodgson, Clayton Yates, Rick Kittles, Dhananjay A Chitale, Haythem Y Ali, S David Nathanson, Petros Nikolinakos, Lisa A Newman, Michele Monteil, and Melissa B Davis

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Evaluation of the impact of thyroiditis development in patients receiving immunotherapy with programmed cell death-1 inhibitors., Matthew Lei, Angela Michael, Seema Patel, and Ding Wang

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US Cancer Centers of Excellence Strategies for Increased Inclusion of Racial and Ethnic Minorities in Clinical Trials., Jeanne M Regnante, Nicole A Richie, Lola Fashoyin-Aje, Michelle Vichnin, Marvella Ford, Upal Basu Roy, Kenneth Turner, Laura Lee Hall, Evelyn Gonzalez, Nestor Esnaola, Luther T Clark, Homer C Adams, Olatunji B Alese, Keerthi Gogineni, Lorna McNeill, Daniel Petereit, Ify Sargeant, Julie Dang, Coleman Obasaju, Quita Highsmith, Simon Craddock Lee, Spencer C Hoover, Erin L Williams, and Moon S Chen

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Colorectal Cancer and Nutrition., Kannan Thanikachalam and Gazala Khan

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Development of an algorithm for the systematic evaluation of patients with suspected heparin-induced thrombocytopenia., Julie Thomson, Philip Kuriakose, Long To, Michael Peters, and James Kalus

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Computationally Assisted Discovery and Assignment of a Highly Strained and PANC-1 Selective Alkaloid from Alaska's Deep Ocean., Yike Zou, Xiaojuan Wang, James Sims, Bin Wang, Pankaj Pandey, Colin L Welsh, Robert P Stone, Mitchell A Avery, Robert J Doerksen, Daneel Ferreira, Clemens Anklin, Frederick A Valeriote, Michelle Kelly, and Mark T Hamann

Submissions from 2018

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A Lesion on the Scalp., Zaid Abdel-Rahman, Kedar Inamdar, and Haythem Y Ali

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Phase 1 study of seviteronel, a selective CYP17 lyase and androgen receptor inhibitor, in women with estrogen receptor-positive or triple-negative breast cancer., Aditya Bardia, Ayca Gucalp, Noashir DaCosta, Nashat Gabrail, Michael Danso, Haythem Y Ali, Kimberly L Blackwell, Lisa A Carey, Joel R Eisner, Edwina S Baskin-Bey, and Tiffany A Traina

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Harnessing a Different Dependency: How to Identify and Target Androgen Receptor-Positive Versus Quadruple-Negative Breast Cancer., Jessica L Christenson, Jane B Trepel, Haythem Y Ali, Sunmin Lee, Joel R Eisner, Edwina S Baskin-Bey, Anthony D Elias, and Jennifer K Richer

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Harnessing a Different Dependency: How to Identify and Target Androgen Receptor-Positive Versus Quadruple-Negative Breast Cancer., Jessica L Christenson, Jane B Trepel, Haythem Y Ali, Sunmin Lee, Joel R Eisner, Edwina S Baskin-Bey, Anthony D Elias, and Jennifer K Richer

Neoadjuvant phase II trial of chemo-radiotherapy (CRT) in patients with resectable (R) and borderline resectable (BR) pancreatic ductal adenocarcinoma (PDA)., V Damarla, Irina Dobrosotskaya, F Siddiqui, Ira Wollner, Mohammad Raoufi, Jia Li, D Kwon, and Gazala Khan

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Venetoclax, bendamustine, and rituximab in patients with relapsed or refractory NHL: a phase Ib dose-finding study., S de Vos, L J Swinnen, Ding Wang, E Reid, N Fowler, J Cordero, M Dunbar, S H Enschede, C Nolan, A M Petrich, J A Ross, A H Salem, M Verdugo, S Agarwal, L Zhou, M Kozloff, L J Nastoupil, and C R Flowers

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Unexplained pancytopenia in acute myeloid leukemia treatment., Daniel Ezekwudo, Oleksandra Lupak, Raju Vaddepally, Bolanle Gbadamosi, and Philip Kuriakose

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Phase 1b investigation of the MEK inhibitor binimetinib in patients with advanced or metastatic biliary tract cancer., R S Finn, D H Ahn, M M Javle, B R Tan, C D Weekes, J C Bendell, A Patnaik, Gazala Khan, D Laheru, R Chavira, J Christy-Bittel, E Barrett, M B Sawyer, and Tanios S Bekaii-Saab

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A Retrospective Study Analyzing the Appropriateness of Initial Treatment of, Aaron Fisher, Pradeep Khanal, Ewa Gniado, Leila Khaddour, Molly Orosey, Ismail Hader, Siddhartha Yadav, and Alexandra Halalau

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Nab-paclitaxel-based therapy in underserved patient populations: The abound.Ps2 study in patients with nsclc and a performance status of 2., Ajeet Gajra, Nagla Abdel Karim, Deborah A Mulford, Liza Cosca Villaruz, Marc Ryan Matrana, Haythem Y Ali, Edgardo S Santos, Tymara Berry, Teng Jin Ong, Alexandra Sanford, Katayoun Amiri, and David R Spigel

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Management of haemophilia carriers around the time of their delivery: Phenotypic variation requiring customization of management., M R Girgis, L Gusba, and Philip Kuriakose

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Genitourinary Pathology Reporting Parameters Most Relevant to the Medical Oncologist., Clara Hwang

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Enrichment and mutation detection of circulating tumor cells from blood samples., Ruqin Kou, Jian Zhao, Priya Gogoi, Shannon Carskadon, Will Chow, Clara Hwang, Nallasivam Palanisamy, Conrad Leung, and Yixin Wang

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Graft-versus-host disease in recipients of male unrelated donor compared with parous female sibling donor transplants., Anita J Kumar, Soyoung Kim, Michael T Hemmer, Mukta Arora, Stephen R Spellman, Joseph A Pidala, Daniel R Couriel, Amin M Alousi, Mahmoud D Aljurf, Jean-Yves Cahn, Mitchell S Cairo, Corey S Cutler, Shatha Farhan, Usama Gergis, Gregory A Hale, Shahrukh K Hashmi, Yoshihiro Inamoto, Rammurti T Kamble, Mohamed A Kharfan-Dabaja, Margaret L MacMillan, David I Marks, Hideki Nakasone, Maxim Norkin, Muna Qayed, Olle Ringden, Harry C Schouten, Kirk R Schultz, Melhem M Solh, Takanori Teshima, Alvaro Urbano-Ispizua, Leo F Verdonck, Robert Peter Gale, Betty K Hamilton, Navneet S Majhail, and Alison W Loren

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The potential of achiral sponge-derived and synthetic bromoindoles as selective cytotoxins against PANC-1 tumor cells., Nicholas Lorig-Roach, Frances Hamkins-Indik, Tyler A Johnson, Karen Tenney, Frederick A Valeriote, and Phillip Crews

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SAPHO Syndrome Masquerading as Metastatic Breast Cancer., Devin Malik, Richa Handa, Andrew Petraszko, and Sheela Tejwani

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Normolipemic Xanthomas in a Patient with Underlying Plasma Cell Dyscrasia., Devin Malik, Sukhpreet Singh, and Akshay Amaraneni

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Breast cancer metastasis through the lympho-vascular system., Saul David Nathanson, David Krag, Henry M Kuerer, Lisa A Newman, Markus Brown, Dontscho Kerjaschki, Ethel R Pereira, and Timothy P Padera

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Utilization of the 21-Gene Recurrence Score in a Diverse Breast Cancer Patient Population: Development of a Clinicopathologic Model to Predict High-Risk Scores and Response to Neoadjuvant Chemotherapy., Ko Un Park, Yalei Chen, Dhananjay A Chitale, Sarah Choi, Haythem Y Ali, Saul David Nathanson, Jessica Bensenhaver, Erica Proctor, Lindsay Petersen, Randa Loutfi, Alyson Simonds, Marcia Kuklinski, Thomas Doyle, Vrushali Dabak, Kim Cole, Melissa B Davis, and Lisa A Newman

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Avelumab in metastatic urothelial carcinoma after platinum failure (JAVELIN Solid Tumor): pooled results from two expansion cohorts of an open-label, phase 1 trial., Manish R Patel, John Ellerton, Jeffrey R Infante, Manish Agrawal, Michael Gordon, Raid Aljumaily, Carolyn D Britten, Luc Dirix, Keun-Wook Lee, Mathew Taylor, Patrick Schöffski, Ding Wang, Alain Ravaud, Arnold B Gelb, Junyuan Xiong, Galit Rosen, James L Gulley, and Andrea B Apolo

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ALK is a critical regulator of the MYC-signaling axis in ALK positive lung cancer., Amanda B Pilling, Jihye Kim, Adriana Estrada-Bernal, Qiong Zhou, Anh T Le, Katherine R Singleton, Lynn E Heasley, Aik Choon Tan, James DeGregori, and Robert C Doebele

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Efficacy and Safety of Sunitinib in Patients with Well-Differentiated Pancreatic Neuroendocrine Tumours., Eric Raymond, Matthew H Kulke, Shukui Qin, Xianjun Yu, Michael Schenker, Antonio Cubillo, Wenhui Lou, Jiri Tomasek, Espen Thiis-Evensen, Jian-Ming Xu, Adina E Croitoru, Mustafa Khasraw, Eva Sedlackova, Ivan Borbath, Paul Ruff, Paul E Oberstein, Tetsuhide Ito, Liqun Jia, Pascal Hammel, Lin Shen, Shailesh V Shrikhande, Yali Shen, Jozef Sufliarsky, Gazala Khan, Chigusa Morizane, Salvatore Galdy, Reza Khosravan, Kathrine C Fernandez, Brad Rosbrook, and Nicola Fazio

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A cross-sectional analysis of cardiovascular disease in the hemophilia population., Suman L Sood, Dunlei Cheng, Margaret Ragni, Craig M Kessler, Doris Quon, Amy D Shapiro, Nigel S Key, Marilyn J Manco-Johnson, Adam Cuker, Christine Kempton, Tzu-Fei Wang, M Elaine Eyster, Philip Kuriakose, Annette von Drygalski, Joan Cox Gill, Allison Wheeler, Peter Kouides, Miguel A Escobar, Cindy Leissinger, Sarah Galdzicka, Marshall Corson, Crystal Watson, and Barbara A Konkle

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Homologous recombination deficiency and host anti-tumor immunity in triple-negative breast cancer., M L Telli, D G Stover, S Loi, S Aparicio, L A Carey, S M Domchek, Lisa A Newman, G W Sledge, and E P Winer

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Computationally Assisted Assignment of the Kadsuraols, a Class of Chemopreventive Agents for the Control of Liver Cancer., Xiaojuan Wang, Jiabao Liu, Pankaj Pandey, Frank R Fronczek, Robert J Doerksen, Jiabao Chen, Xinzhu Qi, Peicheng Zhang, Daneel Ferreira, Frederick A Valeriote, Hua Sun, Shuai Li, and Mark T Hamann

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nab-Paclitaxel plus carboplatin or gemcitabine versus gemcitabine plus carboplatin as first-line treatment of patients with triple-negative metastatic breast cancer: results from the tnAcity trial., D A Yardley, R Coleman, P Conte, J Cortes, A Brufsky, M Shtivelband, R Young, C Bengala, Haythem Y Ali, J Eakel, A Schneeweiss, L de la Cruz-Merino, S Wilks, J O'Shaughnessy, S Glück, H Li, J Miller, D Barton, and N Harbeck

Submissions from 2017

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Clinical impact of metformin in diabetic diffuse large B-cell lymphoma patients: a case-control study., Yaser Alkhatib, Zaid Abdel Rahman, and Philip Kuriakose

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Avelumab, an Anti-Programmed Death-Ligand 1 Antibody, In Patients With Refractory Metastatic Urothelial Carcinoma: Results From a Multicenter, Phase Ib Study., Andrea B Apolo, Jeffrey R Infante, Ani Balmanoukian, Manish R Patel, Ding Wang, Karen Kelly, Anthony E Mega, Carolyn D Britten, Alain Ravaud, Alain C Mita, Howard Safran, Thomas E Stinchcombe, Marko Srdanov, Arnold B Gelb, Michael Schlichting, Kevin Chin, and James L Gulley

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A phase 1 dose-escalation and expansion study of binimetinib (MEK162), a potent and selective oral MEK1/2 inhibitor., Johanna C Bendell, Milind Javle, Tanios S Bekaii-Saab, Richard S Finn, Zev A Wainberg, Daniel A Laheru, Colin D Weekes, Benjamin R Tan, Gazala Khan, Mark M Zalupski, Jeffrey R Infante, Suzanne Jones, Kyriakos P Papadopoulos, Anthony W Tolcher, Renae E Chavira, Janna L Christy-Bittel, Emma Barrett, and Amita Patnaik

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Role of Kindness in Cancer Care., Leonard L Berry, Tracey S Danaher, Robert A Chapman, and Rana Awdish

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Chimerism in Myeloid Malignancies following Stem Cell Transplantation Using FluBu4 with and without Busulfan Pharmacokinetics versus BuCy., Shatha Farhan, Michael Bazydlo, Klodiana Neme, Nancy Mikulandric, Edward Peres, and Nalini Janakiraman

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Phase 2, randomized, double-blind study of pracinostat in combination with azacitidine in patients with untreated, higher-risk myelodysplastic syndromes., Guillermo Garcia-Manero, Guillermo Montalban-Bravo, Jesus G Berdeja, Yasmin Abaza, Elias Jabbour, James Essell, Roger M Lyons, Farhad Ravandi, Michael Maris, Brian Heller, Amy E DeZern, Sunil Babu, David Wright, Bertrand Anz, Ralph Boccia, Rami S Komrokji, Philip Kuriakose, James Reeves, Mikkael A Sekeres, Hagop M Kantarjian, Richard Ghalie, and Gail J Roboz

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Avelumab for patients with previously treated metastatic or recurrent non-small-cell lung cancer (JAVELIN Solid Tumor): dose-expansion cohort of a multicentre, open-label, phase 1b trial., James L Gulley, Arun Rajan, David R Spigel, Nicholas Iannotti, Jason Chandler, Deborah J L Wong, Joseph Leach, W Jeff Edenfield, Ding Wang, Hans Juergen Grote, Anja von Heydebreck, Kevin Chin, Jean-Marie Cuillerot, and Karen Kelly

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Another Look at Pyrroloiminoquinone Alkaloids-Perspectives on Their Therapeutic Potential from Known Structures and Semisynthetic Analogues., Sheng Lin, Erin P McCauley, Nicholas Lorig-Roach, Karen Tenney, Cassandra N Naphen, Ai-Mei Yang, Tyler A Johnson, Thalia Hernadez, Ramandeep Rattan, Frederick A Valeriote, and Phillip Crews

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Renal Complications of Hematopoietic Stem Cell Transplantation: Report of a Case and Review of the Literature., E Liquete, Sean R Williamson, Nalini Janakiraman, and K K Venkat

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A Noninvasive Blood-based Combinatorial Proteomic Biomarker Assay to Detect Breast Cancer in Women Under the Age of 50 Years., Ana P Lourenco, Kasey L Benson, Meredith C Henderson, Michael Silver, Elias Letsios, Quynh Tran, Kelly J Gordon, Sherri Borman, Christa Corn, Rao Mulpuri, Wendy Smith, Josie Alpers, Carrie Costantini, Nitin Rohatgi, Rebecca Yang, Haythem Y Ali, Shah Biren, Michael Morris, Fred Kass, and David E Reese

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Investigation of the Physical and Bioactive Properties of Bromo- and Iodo-Containing Sponge-Derived Compounds Possessing an Oxyphenylethanamine Core., Erin P McCauley, Hanh Lam, Nicholas Lorig-Roach, Justin Luu, Cameron Lloyd, Karen Tenney, Halina Pietraszkiewicz, Cristina Diaz, Frederick A Valeriote, Victoria Auerbuch, and Phillip Crews

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Increasing use of allogeneic hematopoietic cell transplantation in patients aged 70 years and older in the United States., Lori Muffly, Marcelo C Pasquini, Michael Martens, Ruta Brazauskas, Xiaochun Zhu, Kehinde Adekola, Mahmoud Aljurf, Karen K Ballen, Ashish Bajel, Frederic Baron, Minoo Battiwalla, Amer Beitinjaneh, Jean-Yves Cahn, Mathew Carabasi, Yi-Bin Chen, Saurabh Chhabra, Stefan Ciurea, Edward Copelan, Anita D'Souza, John Edwards, James Foran, Cesar O Freytes, Henry C Fung, Robert Peter Gale, Sergio Giralt, Shahrukh K Hashmi, Gerhard C Hildebrandt, Vincent Ho, Ann Jakubowski, Hillard Lazarus, Marlise R Luskin, Rodrigo Martino, Richard Maziarz, Philip McCarthy, Taiga Nishihori, Rebecca Olin, Richard F Olsson, Attaphol Pawarode, Edward Peres, Andrew R Rezvani, David Rizzieri, Bipin N Savani, Harry C Schouten, Mitchell Sabloff, Matthew Seftel, Sachiko Seo, Mohamed L Sorror, Jeff Szer, Baldeep M Wirk, William A Wood, and Andrew Artz

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Integrating Molecular Networking and Biological Assays To Target the Isolation of a Cytotoxic Cyclic Octapeptide, Samoamide A, from an American Samoan Marine Cyanobacterium., C Benjamin Naman, Ramandeep Rattan, Svetlana E Nikoulina, John Lee, Bailey W Miller, Nathan A Moss, Lorene Armstrong, Paul D Boudreau, Hosana M Debonsi, Frederick A Valeriote, Pieter C Dorrestein, and William H Gerwick

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Metastatic Cutaneous Melanoma of the Gallbladder., Dhruvan Patel, Shazia Sohrawardy, Yub Raj Sedhai, Soney Basnyat, Anisha Daxini, Aparna Basu, Vivek R Mehta, Aasim Mohammed, and Steven Lichtenstein

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IAP Antagonists Enhance Apoptotic Response to Enzalutamide in Castration-Resistant Prostate Cancer Cells via Autocrine TNF-α Signaling., Amanda B Pilling, O Hwang, Alain Boudreault, Alain Laurent, and Clara Hwang

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Overall survival analysis of EXAM, a phase III trial of cabozantinib in patients with radiographically progressive medullary thyroid carcinoma., M Schlumberger, R Elisei, S Müller, P Schöffski, M Brose, M Shah, L Licitra, J Krajewska, M C Kreissl, B Niederle, E E W Cohen, L Wirth, Haythem Y Ali, D O Clary, Y Yaron, M Mangeshkar, D Ball, B Nelkin, and S Sherman

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Combination of Carmustine and Selenite Inhibits EGFR Mediated Growth Signaling in Androgen-Independent Prostate Cancer Cells., Vijayalakshmi Thamilselvan, Mani Menon, Gary S Stein, Frederick A Valeriote, and Sivagnanam Thamilselvan

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Solitary Skeletal Muscle Metastasis as First Site of Recurrence of Cervical Cancer: A Case Report., Indumathy Varadarajan, Aparna Basu, Sherri Besmer, Jaganmohan Poli, Scott Richard, and Michael Styler

Submissions from 2016

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Immunotherapy: A New Approach to Treating Multiple Myeloma with Daratumumab and Elotuzumab., Salma Afifi, Alexander T. Michaels, and Alexander Lesokhin