Scholarly journal articles authored by members of the Department of Neurology at Henry Ford Health.

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Submissions from 2017

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Changes in structure and perfusion of grey matter tissues during recovery from Ischaemic subcortical stroke: a longitudinal MRI study, Xinfeng Yu, Linglin Yang, Ruirui Song, Yerfan Jiaerken, Jun Yang, Min Lou, Quan Jiang, and Minming Zhang

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MiR-146a promotes remyelination in a cuprizone model of demyelinating injury, Jing Zhang, Zhenggang Zhang, Mei Lu, Xinli Wang, Xia Shang, Stanton B. Elias, and Michael Chopp

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Demonstration of therapeutic window of Cerebrolysin in embolic stroke: A prospective, randomized, blinded, and placebo-controlled study, Li Zhang, Michael Chopp, Mei Lu, Talan Zhang, Chao Li, Stefan Winter, Hemma Brandstaetter, Edith Doppler, Dieter Meier, Pardeep Pabla, and Zhenggang Zhang

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Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves functional recovery in rats after traumatic brain injury, Yanlu Zhang, Michael Chopp, Zhenggang Zhang, Mark Katakowski, Hongqi Xin, Changsheng Qu, Meser M. Ali, Asim Mahmood, and Ye Xiong

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Treatment of traumatic brain injury in rats with N-acetyl-seryl-aspartyl-lysyl-proline, Yanlu Zhang, Zhenggang Zhang, Michael Chopp, Yuling Meng, Li Zhang, Asim Mahmood, and Ye Xiong

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Treatment of traumatic brain injury in rats with N-acetyl-seryl-aspartyl-lysyl-proline, Yanlu Zhang, Zhenggang Zhang, Michael Chopp, Yuling Meng, Li Zhang, Asim Mahmood, and Ye Xiong

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Exosomes Derived from Mesenchymal Stromal Cells Promote Axonal Growth of Cortical Neurons, Yi Zhang, Michael Chopp, Xian S. Liu, Mark Katakowski, Xinli Wang, Xinchu Tian, David Wu, and Zhenggang Zhang

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Erythropoietin regulates immune/inflammatory reaction and improves neurological function outcomes in traumatic brain injury, Zi-Wei Zhou, Fei Li, Zhi-Tong Zheng, Ya-Dan Li, Tong-Heng Chen, Wei-Wei Gao, Jieli Chen, and Jian-Ning Zhang

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Cold water swimming pretreatment reduces cognitive deficits in a rat model of traumatic brain injury, Zi-Wei Zhou, Ya-Dan Li, Wei-Wei Gao, Jieli Chen, Shu-Yuan Yue, and Jian-Ning Zhang

Submissions from 2016

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Chimeric Mouse model to track the migration of bone marrow derived cells in glioblastoma following anti-angiogenic treatments, B R. Achyut, Adarsh Shankar, A SM Iskander, Roxan Ara, Robert A. Knight, Alfonso G. Scicli, and Ali S. Arbab

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First translational 'Think Tank' on cerebrovascular disease, cognitive impairment and dementia, Frank C. Barone, Deborah Gustafson, Howard A. Crystal, Herman Moreno, Mateusz G. Adamski, Ken Arai, Alison E. Baird, Clotilde Balucani, Adam M. Brickman, David Cechetto, Philip Gorelick, Geert J. Biessels, Amanda Kiliaan, Lenore Launer, Julie Schneider, Farzaneh A. Sorond, Rachel Whitmer, Clinton Wright, and Zhenggang Zhang

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Magnetoencephalography shows atypical sensitivity to linguistic sound sequences in autism spectrum disorder, Jonathan R. Brennan, Neelima Wagley, Ioulia Kovelman, Susan M. Bowyer, Annette E. Richard, and Renee Lajiness-O'Neill

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MiR-126 Contributes to Human Umbilical Cord Blood Cell-Induced Neurorestorative Effects After Stroke in Type-2 Diabetic Mice, Jieli Chen, Ruizhuo Ning, Alex Zacharek, Chengcheng Cui, Xu Cui, Tao Yan, Poornima Venkat, Yi Zhang, and Michael Chopp

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Neurologic Complications in Pregnancy, Mauricio R. Cuero and Panayiotis N. Varelas

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miR-145 Regulates Diabetes-Bone Marrow Stromal Cell-Induced Neurorestorative Effects in Diabetes Stroke Rats, Chengcheng Cui, Xinchun Ye, Michael Chopp, Poornima Venkat, Alex Zacharek, Tao Yan, Ruizhou Ning, Peng Yu, Guiyun Cui, and Jieli Chen

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D-4F Decreases White Matter Damage After Stroke in Mice, Xu Cui, Michael Chopp, Alex Zacharek, Chengcheng Cui, Tao Yan, Ruizhuo Ning, and Jieli Chen

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Cell Treatment for Stroke in Type Two Diabetic Rats Improves Vascular Permeability Measured by MRI, Guangliang Ding, Jieli Chen, Michael Chopp, Lian Li, Tao Yan, Qingjiang Li, Chengcheng Cui, Siamak P. Nejad-Davarani, and Quan Jiang

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Spectroscopic Characterization of the 3+ and 2+ Oxidation States of Europium in a Macrocyclic Tetraglycinate Complex, Levi A. Ekanger, Devin R. Mills, Meser M. Ali, Lisa A. Polin, Yimin Shen, E M. Haacke, and Matthew J. Allen

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Neurogenic orthostatic hypotension and supine hypertension in Parkinson's disease and related synucleinopathies: prioritisation of treatment targets, Alberto J. Espay, Peter A. LeWitt, Robert A. Hauser, Aristide Merola, Mario Masellis, and Anthony E. Lang

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Targeted Theranostic Approach for Glioma Using Dendrimer-Based Curcumin Nanoparticle, N H. Gamage, Li Jing, Maria Worsham, and Meser M. Ali

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American Academy of Neurology Guidelines and the Neurologic Determination of Death-Reply, David M. Greer, Panayiotis N. Varelas, and Eelco FM Wijdicks

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Variability of Brain Death Policies in the United States, David M. Greer, Hilary H. Wang, Jennifer D. Robinson, Panayiotis N. Varelas, Galen V. Henderson, and Eelco FM Wijdicks

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Evaluating and Managing Sleep Disorders in the Parkinson's Disease Clinic, S Gulyani, R Salas, Z Mari, S Choi, A Mahajan, and C Gamaldo

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Imaging of Cerebrovascular Disease in Pregnancy and the Puerperium, Lotfi Hacein-Bey, Panayiotis N. Varelas, John L. Ulmer, Leighton P. Mark, Kesav Raghavan, and James M. Provenzale

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Folic acid tagged nanoceria as a novel therapeutic agent in ovarian cancer, Miriana Hijaz, Soumen Das, Ismail Mert, Ankur Gupta, Zaid Al-Wahab, Calvin Tebbe, Sajad Dar, Jasdeep Chhina, Shailendra Giri, Adnan R. Munkarah, Sudipta Seal, and Ramandeep Rattan

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pH-Dependent Cellular Internalization of Paramagnetic Nanoparticle, Brana Janic, Mohammed P. Bhuiyan, James R. Ewing, and Meser M. Ali

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MicroRNA 146a locally mediates distal axonal growth of dorsal root ganglia neurons under high glucose and sildenafil conditions, Longfei Jia, Lei Wang, Michael Chopp, Yi Zhang, Alexandra Szalad, and Zhenggang Zhang

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Magnetic resonance imaging and cell-based neurorestorative therapy after brain injury, Quan Jiang

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Targeting Glioma with a Dual Mode Optical and Paramagnetic Nanoprobe across the Blood-brain Tumor Barrier, Kishor Karki, James R. Ewing, and Meser M. Ali

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Class IIa histone deacetylases affect neuronal remodeling and functional outcome after stroke, Haifa Kassis, Amjad Shehadah, Chao Li, Yi Zhang, Yisheng Cui, Cynthia Roberts, Neema S. Sadry, Xian-Shuang Liu, Michael Chopp, and Zhenggang Zhang

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Density-Dependent Regulation of Glioma Cell Proliferation and Invasion Mediated by miR-9, Mark Katakowski, Nicholas Charteris, Michael Chopp, and Evgeniy Khain

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Exosomes as Tools to Suppress Primary Brain Tumor, Mark Katakowski and Michael Chopp

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A Prospective Safety Trial of Atorvastatin Treatment to Assess Rebleeding after Spontaneous Intracerebral Hemorrhage: A Serial MRI Investigation, Robert A. Knight, Tavarekere N. Nagaraja, Lian Li, Quan Jiang, Kelly M. Tundo, Michael Chopp, and Donald Seyfried

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5-Aminoimidazole-4-carboxamide ribonucleoside-mediated adenosine monophosphate-activated protein kinase activation induces protective innate responses in bacterial endophthalmitis, Ajay Kumar, Shailendra Giri, and Ashok Kumar

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Organ support after death by neurologic criteria: Results of a survey of US neurologists, Ariane Lewis, Nellie Adams, Panayiotis N. Varelas, David Greer, and Arthur Caplan

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Controversies After Brain Death: When Families Ask for More, Ariane Lewis, Panayiotis N. Varelas, and David Greer

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Pregnancy and Brain Death: Lack of Guidance in US Hospital Policies, Ariane Lewis, Panayiotis N. Varelas, and David Greer

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Prolonging Support After Brain Death: When Families Ask for More, Ariane Lewis, Panayiotis N. Varelas, and David Greer

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New levodopa therapeutic strategies, Peter A. LeWitt

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Levodopa therapy for Parkinson disease: A look backward and forward, Peter A. LeWitt and Stanley Fahn

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A randomized trial of inhaled levodopa (CVT-301) for motor fluctuations in Parkinson's disease, Peter A. LeWitt, Robert A. Hauser, Donald G. Grosset, Fabrizio Stocchi, Marie-Helene Saint-Hilaire, Aaron Ellenbogen, Mika Leinonen, Neil B. Hampson, Tia DeFeo-Fraulini, Martin I. Freed, and Karl D. Kieburtz

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The Efficacy Profile of Rotigotine During the Waking Hours in Patients With Advanced Parkinson's Disease: A Post Hoc Analysis, Peter A. LeWitt, Werner Poewe, Lawrence W. Elmer, Mahnaz Asgharnejad, Babak Boroojerdi, Frank Grieger, and Lars Bauer

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DUSTER: dynamic contrast enhance up-sampled temporal resolution analysis method, Gilad Liberman, Yoram Louzoun, Moran Artzi, Guy Nadav, James R. Ewing, and Dafna Ben Bashat

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Estimation of Tumor Interstitial Fluid Pressure (TIFP) Noninvasively, Long J. Liu, Stephen L. Brown, James R. Ewing, Brigitte D. Ala, Kenneth M. Schneider, and Mordechay Schlesinger

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Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke, Zhongwu Liu and Michael Chopp

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Age-Related Decrease in Heat Shock 70-kDa Protein 8 in Cerebrospinal Fluid Is Associated with Increased Oxidative Stress, David A. Loeffler, Andrea C. Klaver, Mary P. Coffey, Jan O. Aasly, and Peter A. LeWitt

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Nocardia asteroides-Induced movement abnormalities in mice: Relevance for Parkinson's disease?, David A. Loeffler, Peter A. LeWitt, and Dianne M. Camp

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CSF Nrf2 and HSPA8 in Parkinson's disease patients with and without LRRK2 gene mutations, David A. Loeffler, Lynnae M. Smith, Mary P. Coffey, Jan O. Aasly, and Peter A. LeWitt

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Epidemiology of inpatient stay in Parkinson's disease in the United States: Insights from the Nationwide Inpatient Sample, Abhimanyu Mahajan, Poojitha Balakrishnan, Achint Patel, Ioannis Konstantinidis, Dominic Nistal, Narender Annapureddy, Priti Poojary, Girish N. Nadkarni, and Christos Sidiropoulos

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AMP-Activated Protein Kinase Suppresses Autoimmune Central Nervous System Disease by Regulating M1-Type Macrophage-Th17 Axis, Ashutosh K. Mangalam, Ramandeep Rattan, Hamid Suhail, Jaspreet Singh, Nasrul Hoda, Mandar Deshpande, Sadanand Fulzele, Alexander Denic, Viji Shridhar, Ashok Kumar, Benoit Viollet, Moses Rodriguez, and Shailendra Giri

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Increasing the yield of atrial fibrillation detection in cryptogenic stroke using risk factor stratification: a more satisfying approach, Daniel J. Miller

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The Evolution and Application of Cardiac Monitoring for Occult Atrial Fibrillation in Cryptogenic Stroke and TIA, Daniel J. Miller, Kavit Shah, Sumul Modi, Abhimanyu Mahajan, Salman Zahoor, and Muhammad Affan

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Neuroleptic Malignant Syndrome: Complications, Outcomes, and Mortality, Sumul Modi, Devanshi Dharaiya, Lonni Schultz, and Panayiotis N. Varelas

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Predictors of Prolonged Hospital Stay in Status Migrainosus, Sumul Y. Modi, Devanshi Dharaiya, Angelos Katramados, and Panayiotis Mitsias

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Targeting of free fatty acid receptor 1 in EOC: A novel strategy to restrict the adipocyte-EOC dependence, Adnan R. Munkarah, Ismail Mert, Jasdeep Chhina, Hamid Suhail, Laila M. Poisson, Sharon Hensley-Alford, Shailendra Giri, and Ramandeep Rattan

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Predictors of Venous Thromboembolism in Patients with Glioblastoma, Shahzaib Nabi, Pushpinderdeep Kahlon, Farshid Bozorgnia, Adeel Arshad, Tom Mikkelsen, and Vijayalakshmi Donthireddy

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MEG Coherence and DTI Connectivity in mTLE, Mohammad-Reza Nazem-Zadeh, Susan M. Bowyer, John E. Moran, Esmaeil Davoodi-Bojd, Andrew Zillgitt, Barbara J. Weiland, Hassan Bagher-Ebadian, Fariborz Mahmoudi, Kost Elisevich, and Hamid Soltanian-Zadeh

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DTI-based response-driven modeling of mTLE laterality, Mohammad-Reza Nazem-Zadeh, Kost Elisevich, Ellen L. Air, Jason M. Schwalb, George Divine, Manpreet Kaur, Vibhangini S. Wasade, Fariborz Mahmoudi, Saeed Shokri, Hassan Bagher-Ebadian, and Hamid Soltanian-Zadeh

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A National Perspective of Do-Not-Resuscitate Order Utilization Predictors in Intracerebral Hemorrhage, Achint A. Patel, Abhimanyu Mahajan, Alexandre Benjo, Vishal B. Jani, Narender Annapureddy, Shiv K. Agarwal, Priya K. Simoes, Krishna C. Pakanati, Vikash Sinha, Ioannis Konstantinidis, Ambarish Pathak, and Girish N. Nadkarni

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A Nationwide Analysis of Outcomes of Weekend Admissions for Intracerebral Hemorrhage Shows Disparities Based on Hospital Teaching Status, Achint A. Patel, Abhimanyu Mahajan, Alexandre Benjo, Ambarish Pathak, Jitesh Kar, Vishal B. Jani, Narender Annapureddy, Shiv K. Agarwal, Manpreet S. Sabharwal, Priya K. Simoes, Ioannis Konstantinidis, Rabi Yacoub, Fahad Javed, Georges El Hayek, Madhav C. Menon, and Girish N. Nadkarni

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Mesenchymal Stromal Cells Promote Axonal Outgrowth Alone and Synergistically with Astrocytes via tPA, Jian-Yong Qian, Michael Chopp, and Zhongwu Liu

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Psychosis in Parkinson Disease: A Review of Etiology, Phenomenology, and Management, Niyatee Samudra, Neepa Patel, Kyle B. Womack, Pravin Khemani, and Shilpa Chitnis

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Thymosin beta 4 up-regulates miR-200a expression and induces differentiation and survival of rat brain progenitor cells, Manoranjan Santra, Michael Chopp, Sutapa Santra, Ankita Nallani, Shivam Vyas, Zhenggang Zhang, and Daniel C. Morris

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Three-dimensional modeling of Eagle syndrome, Kavit Shah and Daniel J. Miller

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Combination of vatalanib and a 20-HETE synthesis inhibitor results in decreased tumor growth in an animal model of human glioma, Adarsh Shankar, Thaiz F. Borin, Asm Iskander, Nadimpalli R. Varma, Bhagelu R. Achyut, Meenu Jain, Tom Mikkelsen, Austin M. Guo, Wilson B. Chwang, James R. Ewing, Hassan Bagher-Ebadian, and Ali S. Arbab

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Intraoperative MRI for deep brain stimulation lead placement in Parkinson's disease: 1 year motor and neuropsychological outcomes, Christos Sidiropoulos, Richard Rammo, Bradley Merker, Abhimanyu Mahajan, Peter A. LeWitt, Patricia Kaminski, Melissa Womble, Adrianna Zec, Danette Taylor, Julia Wall, and Jason M. Schwalb

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Targeted Stage-Specific Inflammatory microRNA Profiling in Urine During Disease Progression in Experimental Autoimmune Encephalomyelitis: Markers of Disease Progression and Drug Response, Jaspreet Singh, Mandar Deshpande, Hamid Suhail, Ramandeep Rattan, and Shailendra Giri

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Metformin-induced mitochondrial function and ABCD2 up-regulation in X-linked adrenoleukodystrophy involves AMP-activated protein kinase, Jaspreet Singh, Brittany Olle, Hamid Suhail, Michelle M. Felicella, and Shailendra Giri

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Percutaneous transluminal angioplasty and stenting for symptomatic intracranial arterial stenosis: a systematic review and meta-analysis, Georgios Tsivgoulis, Aristeidis H. Katsanos, Georgios Magoufis, Odysseas Kargiotis, Georgios Papadimitropoulos, Konstantinos Vadikolias, Theodoros Karapanayiotides, John Ellul, Anne W. Alexandrov, Panayiotis Mitsias, and Andrei V. Alexandrov

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Modern Approach to Brain Death, Panayiotis N. Varelas and Ariane Lewis

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New insights into coupling and uncoupling of cerebral blood flow and metabolism in the brain, Poornima Venkat, Michael Chopp, and Jieli Chen

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Myelin-targeted, texaphyrin-based multimodal imaging agent for magnetic resonance and optical imaging, Sashiprabha M. Vithanarachchi, Casey D. Foley, Sarah Trimpin, James R. Ewing, Meser M. Ali, and Matthew J. Allen

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Impact of provider level, training and gender on the utilization of palliative care and hospice in neuro-oncology: a North-American survey, Tobias Walbert, Michael Glantz, Lonni Schultz, and Vinay K. Puduvalli

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End-of-life care in patients with primary malignant brain tumors: early is better, Tobias Walbert and Andrea Pace

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Atorvastatin enhances angiogenesis to reduce subdural hematoma in a rat model, Dong Wang, Tuo Li, Huijie Wei, Yi Wang, Guili Yang, Ye Tian, Zilong Zhao, Liang Wang, Shengping Yu, Yongqiang Zhang, Jieli Chen, Rongcai Jiang, and Jian-Ning Zhang

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Tadalafil Promotes the Recovery of Peripheral Neuropathy in Type II Diabetic Mice, Lei Wang, Michael Chopp, Alexandra Szalad, Xuerong Lu, Long-Fei Jia, Mei Lu, Ruilan Zhang, and Zhenggang Zhang

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Controllable yawning expressed as focal seizures of frontal lobe epilepsy, Vibhangini S. Wasade, Indranil Balki, Susan M. Bowyer, Shaila Gaddam, Ali-Reza Mohammadi-Nejad, Mohammad-Reza Nazem-Zadeh, Hamid Soltanian-Zadeh, Andrew Zillgitt, and Marianna Spanaki-Varelas

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Neurorestorative Responses to Delayed Human Mesenchymal Stromal Cells Treatment of Stroke in Type 2 Diabetic Rats, Tao Yan, Poornima Venkat, Michael Chopp, Alex Zacharek, Ruizhuo Ning, Cynthia Roberts, Yi Zhang, Mei Lu, and Jieli Chen

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Redox Imbalance and Stroke, Ruidong Ye, Ming Shi, Qian Liu, and Jieli Chen

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Progesterone modulates endothelial progenitor cell (EPC) viability through the CXCL12/CXCR4/PI3K/Akt signalling pathway, Peng Yu, Zhifei Zhang, Shengjie Li, Xiaolong Wen, Wei Quan, Qilong Tian, Jieli Chen, Jianning Zhang, and Rongcai Jiang

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Blood Brain Barrier Disruption in Diabetic Stroke Related to Unfavorable Outcome, Xinfeng Yu, Xiaojun Xu, Alan Jackson, Jianzhong Sun, Peiyu Huang, Yingying Mao, Zhicai Chen, Min Lou, Quan Jiang, and Minming Zhang

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Prominence of Medullary Veins on Susceptibility-Weighted Images Provides Prognostic Information in Patients with Subacute Stroke, X Yu, L Yuan, A Jackson, J Sun, P Huang, X Xu, Y Mao, M Lou, Quan Jiang, and M Zhang

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Thymosin beta4 promotes oligodendrogenesis in the demyelinating central nervous system, Jing Zhang, Zhenggang Zhang, Yi Li, Mei Lu, Yi Zhang, Stanton B. Elias, and Michael Chopp

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Cerebrolysin dose-dependently improves neurological outcome in rats after acute stroke: A prospective, randomized, blinded, and placebo-controlled study, Li Zhang, Michael Chopp, Mei Lu, Talan Zhang, Stefan Winter, Edith Doppler, Dieter Meier, Chao Li, Anita Eapen, Pardeep Pabla, and Zhenggang Zhang

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Diabetes Mellitus Impairs Cognitive Function in Middle-Aged Rats and Neurological Recovery in Middle-Aged Rats After Stroke, Li Zhang, Michael Chopp, Yanlu Zhang, Ye Xiong, Chao Li, Neema S. Sadry, Imane A. Rhaleb, Mei Lu, and Zhenggang Zhang

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Targeting Triple Negative Breast Cancer with a Small-sized Paramagnetic Nanoparticle, Li Zhang, Nadimpalli R. Varma, Zhenggang Zhang, James R. Ewing, Ali Arbab, and Meser M. Ali

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Function of neural stem cells in ischemic brain repair processes, Ruilan Zhang, Zhenggang Zhang, and Michael Chopp

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Exosomes in stroke pathogenesis and therapy, Zhenggang Zhang and Michael Chopp

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Neural Stem Cells and Ischemic Brain, Zhenggang Zhang and Michael Chopp

Submissions from 2015

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Metformin prevents aggressive ovarian cancer growth driven by high-energy diet: similarity with calorie restriction, Zaid Al-Wahab, Ismail Mert, Calvin Tebbe, Jasdeep Chhina, Miriana Hijaz, Robert T. Morris, Rouba Ali-Fehmi, Shailendra Giri, Adnan R. Munkarah, and Ramandeep Rattan

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Can big data help us close an epilepsy care gap?, Christine B. Baca and Gregory L. Barkley

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Coding of Neuroinfectious Diseases, Gregory L. Barkley

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Concentration-independent MRI of pH with a dendrimer-based pH-responsive nanoprobe, Mohammed PI Bhuiyan, Madhava P. Aryal, Branislava Janic, Kishor Karki, Nadimpalli RS Varma, James R. Ewing, Ali S. Arbab, and Meser M. Ali

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Epilepsy spectrum disorders: A concept in need of validation or refutation, Nash N. Boutros, Susan M. Bowyer, John Wang, Mian Z. Urfy, and Jeffrey A. Loeb

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MRI-Tracked Tumor Vascular Changes in the Hours after Single-Fraction Irradiation, Stephen L. Brown, Tavarekere N. Nagaraja, Madhava P. Aryal, Swayamprava Panda, Glauber Cabral, Kelly A. Keenan, Rasha Elmghirbi, Tom Mikkelsen, David Hearshen, Robert A. Knight, Ning Wen, Jae-Ho Kim, and James R. Ewing

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Idiopathic spinal cord herniation: an imaging diagnosis with a significant delay, Britton J. Carter, Brent Griffith, Lonni R. Schultz, Muwaffak M. Abdulhak, Daniel Newman, and Rajan Jain

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Emerging potential of exosomes and noncoding microRNAs for the treatment of neurological injury/diseases, Michael Chopp and Zhenggang Zhang

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Super-Refractory Status Epilepticus, Mauricio R. Cuero and Panayiotis N. Varelas

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How neurologists are paid: Part 1: The Medicare payment system, Peter D. Donofrio, Gregory L. Barkley, Bruce H. Cohen, David A. Evans, Gregory J. Esper, Bryan Soronson, Jeffrey R. Buchhalter, and Amanda Becker

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How neurologists are paid: Part 2: Private practice, research grants, academic and nonclinical activities, Peter D. Donofrio, Gregory L. Barkley, Bruce H. Cohen, David A. Evans, Gregory J. Esper, Bryan Soronson, Jeffrey R. Buchhalter, and Amanda Becker